Search Results - "Matteson, Nathaniel L"
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An amplicon-based sequencing framework for accurately measuring intrahost virus diversity using PrimalSeq and iVar
Published in Genome Biology (08-01-2019)“…How viruses evolve within hosts can dictate infection outcomes; however, reconstructing this process is challenging. We evaluate our multiplexed amplicon…”
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Outbreak.info genomic reports: scalable and dynamic surveillance of SARS-CoV-2 variants and mutations
Published in Nature methods (01-04-2023)“…In response to the emergence of SARS-CoV-2 variants of concern, the global scientific community, through unprecedented effort, has sequenced and shared over 11…”
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Epidemiological hypothesis testing using a phylogeographic and phylodynamic framework
Published in Nature communications (06-11-2020)“…Computational analyses of pathogen genomes are increasingly used to unravel the dispersal history and transmission dynamics of epidemics. Here, we show how to…”
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The molecular epidemiology of multiple zoonotic origins of SARS-CoV-2
Published in Science (American Association for the Advancement of Science) (26-08-2022)“…Understanding the circumstances that lead to pandemics is important for their prevention. We analyzed the genomic diversity of severe acute respiratory…”
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Structure-based assessment of protein-protein interactions and accessibility of protein IX in adenoviruses with implications for antigen display
Published in Virology (New York, N.Y.) (01-03-2018)“…The exterior minor protein IX of adenoviruses (AdVs) is a frequent target of attachment of antigens and the modified AdVs are being used as potent vaccine…”
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Emergence of an early SARS-CoV-2 epidemic in the United States
Published in Cell (16-09-2021)“…The emergence of the COVID-19 epidemic in the United States (U.S.) went largely undetected due to inadequate testing. New Orleans experienced one of the…”
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Regional connectivity drove bidirectional transmission of SARS-CoV-2 in the Middle East during travel restrictions
Published in Nature communications (15-08-2022)“…Regional connectivity and land travel have been identified as important drivers of SARS-CoV-2 transmission. However, the generalizability of this finding is…”
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EMPress Enables Tree-Guided, Interactive, and Exploratory Analyses of Multi-omic Data Sets
Published in mSystems (16-03-2021)“…Standard workflows for analyzing microbiomes often include the creation and curation of phylogenetic trees. Here we present EMPress, an interactive web tool…”
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EMPress Enables Tree-Guided, Interactive, and Exploratory Analyses of Multi-omic Data Sets
Published in mSystems (01-04-2021)“…Standard workflows for analyzing microbiomes often include the creation and curation of phylogenetic trees. Here we present EMPress, an interactive web tool…”
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Wastewater sequencing reveals early cryptic SARS-CoV-2 variant transmission
Published in Nature (London) (01-09-2022)“…As SARS-CoV-2 continues to spread and evolve, detecting emerging variants early is critical for public health interventions. Inferring lineage prevalence by…”
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The Use of Genomic Epidemiology in Viral Outbreak Monitoring and Intervention
Published 01-01-2023“…Viral infectious diseases are one of the greatest challenges public health faces. Since the beginning of the 21st century, a number of viruses have emerged…”
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Dissertation -
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Travel Surveillance and Genomics Uncover a Hidden Zika Outbreak during the Waning Epidemic
Published in Cell (22-08-2019)“…The Zika epidemic in the Americas has challenged surveillance and control. As the epidemic appears to be waning, it is unclear whether transmission is still…”
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Integrated Genomic and Social Network Analyses of SARS-CoV-2 Transmission in the Healthcare Setting
Published in Clinical infectious diseases (15-05-2024)“…Infection prevention (IP) measures are designed to mitigate the transmission of pathogens in healthcare. Using large-scale viral genomic and social network…”
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Genomic surveillance reveals dynamic shifts in the connectivity of COVID-19 epidemics
Published in Cell (21-12-2023)“…The maturation of genomic surveillance in the past decade has enabled tracking of the emergence and spread of epidemics at an unprecedented level. During the…”
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Safer at school early alert: an observational study of wastewater and surface monitoring to detect COVID-19 in elementary schools
Published in Lancet Regional Health - Americas (Online) (01-03-2023)“…Schools are high-risk settings for SARS-CoV-2 transmission, but necessary for children's educational and social-emotional wellbeing. Previous research suggests…”
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Safer at school early alert: an observational study of wastewater and surface monitoring to detect COVID-19 in elementary schoolsResearch in context
Published in Lancet Regional Health - Americas (Online) (01-03-2023)“…Background: Schools are high-risk settings for SARS-CoV-2 transmission, but necessary for children's educational and social-emotional wellbeing. Previous…”
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Journal Article