Search Results - "Mattes, Raphael"
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1
Loss of KDM6A confers drug resistance in acute myeloid leukemia
Published in Leukemia (01-01-2020)“…Acute myeloid leukemia (AML) is an aggressive hematologic neoplasm resulting from the malignant transformation of myeloid progenitors. Despite intensive…”
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2
Loss-of-function mutations in the histone methyltransferase EZH2 promote chemotherapy resistance in AML
Published in Scientific reports (12-03-2021)“…Chemotherapy resistance is the main impediment in the treatment of acute myeloid leukaemia (AML). Despite rapid advances, the various mechanisms inducing…”
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Journal Article -
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Evolution of Cytogenetically Normal Acute Myeloid Leukemia During Therapy and Relapse: An Exome Sequencing Study of 50 Patients
Published in Clinical cancer research (01-04-2018)“…To study mechanisms of therapy resistance and disease progression, we analyzed the evolution of cytogenetically normal acute myeloid leukemia (CN-AML) based on…”
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Loss of KDM6A Confers Drug Resistance in Acute Myeloid Leukemia
Published in Blood (29-11-2018)“…Acute myeloid leukemia (AML) is an aggressive hematologic cancer resulting from the malignant transformation of myeloid progenitors. Despite intensive…”
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Journal Article -
5
sCD25 as an independent adverse prognostic factor in adult patients with HLH: results of a multicenter retrospective study
Published in Blood advances (14-03-2023)“…•sCD25 appears to be a valuable adverse prognostic parameter in adult patients with HLH.•The outcome of adult patients with HLH with underlying malignancies is…”
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