Search Results - "Mattes, Daniela S."
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Facile access to potent antiviral quinazoline heterocycles with fluorescence properties via merging metal-free domino reactions
Published in Nature communications (02-05-2017)“…Most of the known approved drugs comprise functionalized heterocyclic compounds as subunits. Among them, non-fluorescent quinazolines with four different…”
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High-flexibility combinatorial peptide synthesis with laser-based transfer of monomers in solid matrix material
Published in Nature communications (14-06-2016)“…Laser writing is used to structure surfaces in many different ways in materials and life sciences. However, combinatorial patterning applications are still…”
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Combinatorial Synthesis of Peptoid Arrays via Laser‐Based Stacking of Multiple Polymer Nanolayers
Published in Macromolecular rapid communications. (01-03-2019)“…Here, the combinatorial synthesis of molecule arrays via a laser‐assisted process is reported. Laser‐transferred polymer nanolayers with embedded monomers,…”
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Miniaturized and Automated Synthesis of Biomolecules—Overview and Perspectives
Published in Advanced materials (Weinheim) (01-06-2019)“…Chemical synthesis is performed by reacting different chemical building blocks with defined stoichiometry, while meeting additional conditions, such as…”
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Automated Laser‐Transfer Synthesis of High‐Density Microarrays for Infectious Disease Screening
Published in Advanced materials (Weinheim) (01-06-2022)“…Laser‐induced forward transfer (LIFT) is a rapid laser‐patterning technique for high‐throughput combinatorial synthesis directly on glass slides. A lack of…”
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Combinatorial Synthesis of Macromolecular Arrays by Microchannel Cantilever Spotting (µCS)
Published in Advanced materials (Weinheim) (02-08-2018)“…Surface‐bound microarrays of multiple oligo‐ and macromolecules (e.g., peptides, DNA) offer versatile options in biomedical applications like drug screening,…”
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On‐Chip Neo‐Glycopeptide Synthesis for Multivalent Glycan Presentation
Published in Chemistry : a European journal (06-08-2020)“…Single glycan–protein interactions are often weak, such that glycan binding partners commonly utilize multiple, spatially defined binding sites to enhance…”
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Selective Functionalization of Microstructured Surfaces by Laser-Assisted Particle Transfer
Published in Advanced functional materials (18-10-2016)“…Microcavity arrays represent millions of different reaction compartments to screen, for example, molecular interactions, exogenous factors for cells or…”
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Laser-induced forward transfer of soft material nanolayers with millisecond pulses shows contact-based material deposition
Published in Applied surface science (01-04-2020)“…[Display omitted] •High-speed imaging shows contact-based deposition mechanism.•Quantification of the free surface expansion and relaxation during the…”
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Cover Feature: On‐Chip Neo‐Glycopeptide Synthesis for Multivalent Glycan Presentation (Chem. Eur. J. 44/2020)
Published in Chemistry : a European journal (06-08-2020)“…Laser‐based patterning technology allows for flexible and rapid on‐surface microarray synthesis of peptide scaffolds. In combination with click chemistry, a…”
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Development of a poly(dimethylacrylamide) based matrix material for solid phase high density peptide array synthesis employing a laser based material transfer
Published in Applied surface science (15-12-2016)“…[Display omitted] •New matrix material for peptide array synthesis from a ‘solid solvent’.•Resolution was increased with possible spot densities of up to…”
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Microcavity Functionalization: Selective Functionalization of Microstructured Surfaces by Laser-Assisted Particle Transfer (Adv. Funct. Mater. 39/2016)
Published in Advanced functional materials (01-10-2016)“…On page 7067, A. Nesterov‐Mueller and co‐workers present a method for the selective functionalization of microcavities with a density of up to 1 million…”
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A Trifunctional Linker for Purified 3D Assembled Peptide Structure Arrays
Published in Small methods (13-02-2018)“…Microarrays are an important tool in modern research that allow the rapid screening of many different interactions simultaneously. Peptide arrays, which bear…”
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Replication of Polymer-Based Peptide Microarrays by Multi-Step Transfer
Published in ChemNanoMat : chemistry of nanomaterials for energy, biology and more (01-09-2016)“…Peptide microarrays serve as a high‐throughput tool for the readout of protein–peptide interactions. We present a multi‐step purification of high‐complexity…”
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