Search Results - "Mattern, J"

Regulation and Role of Fungal Secondary Metabolites by Macheleidt, Juliane, Mattern, Derek J, Fischer, Juliane, Netzker, Tina, Weber, Jakob, Schroeckh, Volker, Valiante, Vito, Brakhage, Axel A

“…Fungi have the capability to produce a tremendous number of so-called secondary metabolites, which possess a multitude of functions, e.g., communication…”
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Microbial communication leading to the activation of silent fungal secondary metabolite gene clusters by Netzker, Tina, Fischer, Juliane, Weber, Jakob, Mattern, Derek J, König, Claudia C, Valiante, Vito, Schroeckh, Volker, Brakhage, Axel A

“…Microorganisms form diverse multispecies communities in various ecosystems. The high abundance of fungal and bacterial species in these consortia results in…”
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Correction: The novel c-Met inhibitor cabozantinib overcomes gemcitabine resistance and stem cell signaling in pancreatic cancer by Hage, C., Rausch, V., Giese, N., Giese, T., Schönsiegel, F., Labsch, S., Nwaeburu, C., Mattern, J., Gladkich, J., Herr, I.

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Correction to: Dexamethasone-induced cisplatin and gemcitabine resistance in lung carcinoma samples treated ex vivo by Gassler, N., Zhang, C., Wenger, T., Schnabel, P. A., Dienemann, H., Debatin, K. -M, Mattern, J., Herr, I.

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Bacillus subtilis attachment to Aspergillus niger hyphae results in mutually altered metabolism by Benoit, Isabelle, van den Esker, Marielle H., Patyshakuliyeva, Aleksandrina, Mattern, Derek J., Blei, Felix, Zhou, Miaomiao, Dijksterhuis, Jan, Brakhage, Axel A., Kuipers, Oscar P., de Vries, Ronald P., Kovács, Ákos T.

“…Summary Interaction between microbes affects the growth, metabolism and differentiation of members of the microbial community. While direct and indirect…”
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Virulence determinants of the human pathogenic fungus Aspergillus fumigatus protect against soil amoeba predation by Hillmann, Falk, Novohradská, Silvia, Mattern, Derek J., Forberger, Tilmann, Heinekamp, Thorsten, Westermann, Martin, Winckler, Thomas, Brakhage, Axel A.

“…Summary Filamentous fungi represent classical examples for environmentally acquired human pathogens whose major virulence mechanisms are likely to have emerged…”
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Synergistic activity of cosecreted natural products from amoebae-associated bacteria by Arp, Johannes, Götze, Sebastian, Mukherji, Ruchira, Mattern, Derek J., García-Altares, María, Klapper, Martin, Brock, Debra A., Brakhage, Axel A., Strassmann, Joan E., Queller, David C., Bardl, Bettina, Willing, Karsten, Peschel, Gundela, Stallforth, Pierre

“…Investigating microbial interactions from an ecological perspective is a particularly fruitful approach to unveil both new chemistry and bioactivity. Microbial…”
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Identification of the antiphagocytic trypacidin gene cluster in the human-pathogenic fungus Aspergillus fumigatus by Mattern, Derek J, Schoeler, Hanno, Weber, Jakob, Novohradská, Silvia, Kraibooj, Kaswara, Dahse, Hans-Martin, Hillmann, Falk, Valiante, Vito, Figge, Marc Thilo, Brakhage, Axel A

“…The opportunistic human pathogen Aspergillus fumigatus produces numerous different natural products. The genetic basis for the biosynthesis of a number of…”
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VEGF expression by mesenchymal stem cells contributes to angiogenesis in pancreatic carcinoma by Beckermann, B M, Kallifatidis, G, Groth, A, Frommhold, D, Apel, A, Mattern, J, Salnikov, A V, Moldenhauer, G, Wagner, W, Diehlmann, A, Saffrich, R, Schubert, M, Ho, A D, Giese, N, Büchler, M W, Friess, H, Büchler, P, Herr, I

“…Little is known about the factors that enable the mobilisation of human mesenchymal stem cells (MSC) from the bone marrow into the blood stream and their…”
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SCF Ubiquitin Ligase F-box Protein Fbx15 Controls Nuclear Co-repressor Localization, Stress Response and Virulence of the Human Pathogen Aspergillus fumigatus by Jöhnk, Bastian, Bayram, Özgür, Abelmann, Anja, Heinekamp, Thorsten, Mattern, Derek J, Brakhage, Axel A, Jacobsen, Ilse D, Valerius, Oliver, Braus, Gerhard H

“…F-box proteins share the F-box domain to connect substrates of E3 SCF ubiquitin RING ligases through the adaptor Skp1/A to Cul1/A scaffolds. F-box protein…”
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Functional Reconstitution of a Fungal Natural Product Gene Cluster by Advanced Genome Editing by Weber, Jakob, Valiante, Vito, Nødvig, Christina S, Mattern, Derek J, Slotkowski, Rebecca A, Mortensen, Uffe H, Brakhage, Axel A

“…Filamentous fungi produce varieties of natural products even in a strain dependent manner. However, the genetic basis of chemical speciation between strains is…”
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Rewiring of the Austinoid Biosynthetic Pathway in Filamentous Fungi by Mattern, Derek J, Valiante, Vito, Horn, Fabian, Petzke, Lutz, Brakhage, Axel A

“…Filamentous fungi produce numerous high-value natural products (NPs). The biosynthetic genes for NPs are normally clustered in the genome. A valuable NP class…”
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The novel c-Met inhibitor cabozantinib overcomes gemcitabine resistance and stem cell signaling in pancreatic cancer by Hage, C, Rausch, V, Giese, N, Giese, T, Schönsiegel, F, Labsch, S, Nwaeburu, C, Mattern, J, Gladkich, J, Herr, I

“…Pancreatic ductal adenocarcinoma (PDA) is one of the most lethal malignancies. Cancer stem cells (CSCs), which are not targeted by current therapies, may be…”
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Efficiency of Bakri intra uterine tamponade balloon use in postpartum hemorrhage: Before and after study by Mattern, J, Sibiude, J, Picone, O, Mandelbrot, L

“…To assess the impact of the introduction of intrauterine balloon tamponade on second-line management practices for post-partum hemorrhage (PPH). This…”
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Simulating sediment–water exchange of nutrients and oxygen: A comparative assessment of models against mesocosm observations by Wilson, Robin F., Fennel, Katja, Paul Mattern, J.

“…How to represent nutrient fluxes resulting from organic matter remineralization in sediments should be an important consideration when formulating a…”
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Discovery of an Extended Austinoid Biosynthetic Pathway in Aspergillus calidoustus by Valiante, Vito, Mattern, Derek J, Schüffler, Anja, Horn, Fabian, Walther, Grit, Scherlach, Kirstin, Petzke, Lutz, Dickhaut, Joachim, Guthke, Reinhard, Hertweck, Christian, Nett, Markus, Thines, Eckhard, Brakhage, Axel A

“…Filamentous fungi produce a wide range of natural products that are commonly used in various industrial contexts (e.g., pharmaceuticals and insecticides)…”
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Synthetic biology of fungal natural products by Mattern, Derek J, Valiante, Vito, Unkles, Shiela E, Brakhage, Axel A

“…Synthetic biology is an ever-expanding field in science, also encompassing the research area of fungal natural product (NP) discovery and production. Until…”
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Continuous exposure of pancreatic cancer cells to dietary bioactive agents does not induce drug resistance unlike chemotherapy by Fan, P, Zhang, Y, Liu, L, Zhao, Z, Yin, Y, Xiao, X, Bauer, N, Gladkich, J, Mattern, J, Gao, C, Schemmer, P, Gross, W, Herr, I

“…The repeated treatment of cancer cells with chemo- or radiotherapy induces therapy resistance, but it was previously unknown whether the same effect occurs…”
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Instability after reverse total shoulder replacement by Gallo, Robert A., MD, Gamradt, Seth C., MD, Mattern, Christopher J., MD, Cordasco, Frank A., MD, Craig, Edward V., MD, Dines, David M., MD, Warren, Russell F., MD

“…Background Despite advances in technique and implant design, instability after reverse total shoulder arthroplasty remains a challenging postoperative…”
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VEGF expression by mesenchymal stem cells contributes to angiogenesis in pancreatic carcinoma by BECKERMANN, B. M, KALLIFATIDIS, G, SAFFRICH, R, SCHUBERT, M, HO, A. D, GIESE, N, BÜCHLER, M. W, FRIESS, H, BBCHLER, P, HERR, I, GROTH, A, FROMMHOLD, D, APEL, A, ATATTERN, J, SALNIKOV, A. V, MOLDENHAUER, G, WAGNER, W, DIEHLMANN, A

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