Search Results - "Matteoli, M"
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Brain mapping across 16 autism mouse models reveals a spectrum of functional connectivity subtypes
Published in Molecular psychiatry (01-12-2021)“…Autism Spectrum Disorder (ASD) is characterized by substantial, yet highly heterogeneous abnormalities in functional brain connectivity. However, the origin…”
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Microglia convert aggregated amyloid-β into neurotoxic forms through the shedding of microvesicles
Published in Cell death and differentiation (01-04-2014)“…Alzheimer’s disease (AD) is characterized by extracellular amyloid- β (A β ) deposition, which activates microglia, induces neuroinflammation and drives…”
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Comparison of two advanced hybrid closed loop in a pediatric population with type 1 diabetes: a real-life observational study
Published in Acta diabetologica (01-07-2022)“…Objective The Advanced Hybrid Closed Loop (AHCL) systems have provided the potential to ameliorate glucose control in children with Type 1 Diabetes. The aim of…”
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Testing Aβ toxicity on primary CNS cultures using drug-screening microfluidic chips
Published in Lab on a chip (07-08-2014)“…Open microscale cultures of primary central nervous system (CNS) cells have been implemented in microfluidic chips that can expose the cells to physiological…”
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Association between SNAP-25 gene polymorphisms and cognition in autism: functional consequences and potential therapeutic strategies
Published in Translational psychiatry (27-01-2015)“…Synaptosomal-associated protein of 25 kDa (SNAP-25) is involved in different neuropsychiatric disorders, including schizophrenia and…”
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Reduced SNAP-25 increases PSD-95 mobility and impairs spine morphogenesis
Published in Cell death and differentiation (01-09-2015)“…Impairment of synaptic function can lead to neuropsychiatric disorders collectively referred to as synaptopathies. The SNARE protein SNAP-25 is implicated in…”
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Correction: Brain mapping across 16 autism mouse models reveals a spectrum of functional connectivity subtypes
Published in Molecular psychiatry (01-09-2022)Get full text
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Monogenic diabetes clinic (MDC): 3-year experience
Published in Acta diabetologica (01-01-2023)“…Aim In the pediatric diabetes clinic, patients with type 1 diabetes mellitus (T1D) account for more than 90% of cases, while monogenic forms represent about…”
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Correction to: Monogenic diabetes clinic (MDC): 3‑year experience
Published in Acta diabetologica (2023)Get full text
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The effects of calcitriol and nicotinamide on residual pancreatic β-cell function in patients with recent-onset Type 1 diabetes (IMDIAB XI)
Published in Diabetic medicine (01-08-2006)“…Background A number of recent studies underline the importance of vitamin D in the pathogenesis of Type 1 diabetes (T1D). Aims The aim of this study was to…”
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The synaptic split of SNAP-25: Different roles in glutamatergic and GABAergic neurons?
Published in Neuroscience (2009)Get full text
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No effect of oral insulin on residual beta-cell function in recent-onset Type I diabetes (the IMDIAB VII)
Published in Diabetologia (09-08-2000)“…Aims/hypothesis. Induction of tolerance to insulin is achievable in animal models of Type I (insulin-dependent) Diabetes mellitus by oral treatment with this…”
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Analysis of SNAP-25 immunoreactivity in hippocampal inhibitory neurons during development in culture and in situ
Published in Neuroscience (2005)“…Synaptosomal associated protein of 25 kDa (SNAP-25) is a component of the soluble N-ethylmaleimide-sensitive fusion protein (NSF) attachment protein receptor…”
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A randomized trial of nicotinamide and vitamin E in children with recent onset type 1 diabetes (IMDIAB IX)
Published in European journal of endocrinology (01-05-2004)“…Various adjuvant therapies have been introduced along with intensive insulin therapy in patients with recent onset type 1 diabetes. Nicotinamide (NA),…”
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A two year observational study of nicotinamide and intensive insulin therapy in patients with recent onset type 1 diabetes mellitus
Published in Journal of pediatric endocrinology & metabolism : JPEM (01-08-2005)“…A number of trials have evaluated residual beta-cell function in patients with recent onset type 1 diabetes mellitus (DM1) treated with nicotinamide in…”
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Synaptogenesis in hippocampal cultures
Published in Cellular and molecular life sciences : CMLS (30-08-1999)“…Hippocampal cultures offer unique advantages for the study of neuronal development and synaptogenesis. Studies performed on this model enabled dissection of…”
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GABA and pancreatic beta‐cells: colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic‐like microvesicles suggests their role in GABA storage and secretion
Published in The EMBO journal (01-05-1991)“…GABA, a major inhibitory neurotransmitter of the brain, is also present at high concentration in pancreatic islets. Current evidence suggests that within…”
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Incidence of insulin-dependent diabetes mellitus among Sardinian-heritage children born in Lazio region, Italy
Published in The Lancet (British edition) (18-01-1997)“…The relative importance of genetic and environmental factors in causing insulin-dependent diabetes mellitus (IDDM) is unknown. We studied this question by…”
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Insulin VNTR allele-specific effect in type 1 diabetes depends on identity of untransmitted paternal allele
Published in Nature genetics (01-11-1997)Get full text
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Exo-Endocytotic Recycling of Synaptic Vesicles in Developing Processes of Cultured Hippocampal Neurons
Published in The Journal of cell biology (01-05-1992)“…In mature neurons synaptic vesicles (SVs) undergo cycles of exo-endocytosis at synapses. It is currently unknown whether SV exocytosis and recycling occurs…”
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