Search Results - "Matteoli, G"

Human intestinal epithelial cells promote the differentiation of tolerogenic dendritic cells by Iliev, I D, Spadoni, I, Mileti, E, Matteoli, G, Sonzogni, A, Sampietro, G M, Foschi, D, Caprioli, F, Viale, G, Rescigno, M

“…In mice, a subpopulation of gut dendritic cells (DCs) expressing CD103 drives the development of regulatory T (T(reg)) cells. Further, it was recently…”
Get more information

Abdominal vagus nerve stimulation as a new therapeutic approach to prevent postoperative ileus by Stakenborg, N., Wolthuis, A. M., Gomez‐Pinilla, P. J., Farro, G., Di Giovangiulio, M., Bosmans, G., Labeeuw, E., Verhaegen, M., Depoortere, I., D'Hoore, A., Matteoli, G., Boeckxstaens, G. E.

“…Background Electrical stimulation of the cervical vagus nerve (VNS) prevents postoperative ileus (POI) in mice. As this approach requires an additional…”
Get full text

Intestinal epithelial cells promote colitis-protective regulatory T-cell differentiation through dendritic cell conditioning by Iliev, I D, Mileti, E, Matteoli, G, Chieppa, M, Rescigno, M

“…Intestinal dendritic cells (DCs) have been shown to display specialized functions, including the ability to promote gut tropism to lymphocytes, to polarize…”
Get full text

Gut CD103+ dendritic cells express indoleamine 2,3-dioxygenase which influences T regulatory/T effector cell balance and oral tolerance induction by Matteoli, Gianluca, Mazzini, Elisa, Iliev, Iliyan D, Mileti, Erika, Fallarino, Francesca, Puccetti, Paolo, Chieppa, Marcello, Rescigno, Maria

“…CD103(+) gut dendritic cells (DCs) have been shown to be required for de novo conversion of adaptive T regulatory (Treg) cells. Indoleamine 2,3-dioxygenase…”
Get more information

Estrogen receptor β controls proliferation of enteric glia and differentiation of neurons in the myenteric plexus after damage by D’Errico, F., Goverse, G., Dai, Y., Wu, W., Stakenborg, M., Labeeuw, E., De Simone, V., Verstockt, B., Gomez-Pinilla, P. J., Warner, M., Di Leo, A., Matteoli, G., Gustafsson, J. A.

“…Injury to the enteric nervous system (ENS) can cause several gastrointestinal (GI) disorders including achalasia, irritable bowel syndrome, and gastroparesis…”
Get full text

Smooth muscle and neural dysfunction contribute to different phases of murine postoperative ileus by Farro, G., Gomez‐Pinilla, P. J., Di Giovangiulio, M., Stakenborg, N., Auteri, M., Thijs, T., Depoortere, I., Matteoli, G., Boeckxstaens, G. E.

“…Background Postoperative ileus (POI) is characterized by a transient inhibition of gastrointestinal (GI) motility after abdominal surgery mediated by the…”
Get full text

The vagal innervation of the gut and immune homeostasis by Matteoli, G, Gomez-Pinilla, P.J, Di Giovangiulio, M, Stakenborg, N, Boeckxstaens, G.E

Get full text

Ghrelin receptor modulates T helper cells during intestinal inflammation by Di Giovangiulio, M., Stakenborg, N., Bosmans, G., Meroni, E., Farro, G., Gomez‐Pinilla, P. J., Depoortere, I., Boeckxstaens, G. E., Matteoli, G.

“…Background The orexigenic peptide ghrelin has anti‐inflammatory properties in colitis, however, the mechanism of action and the immune cells targeted remain…”
Get full text

Systemic inflammation with enhanced brain activation contributes to more severe delay in postoperative ileus by Bree, S. H. W., Cailotto, C., Di Giovangiulio, M., Jansen, E., Vliet, J., Costes, L., Depoortere, I., Gomez‐Pinilla, P. J., Matteoli, G., Boeckxstaens, G. E. E.

“…Background The severity of postoperative ileus (POI) has been reported to result from decreased contractility of the muscularis inversely related to the number…”
Get full text

Role of connexin-43 hemichannels in the pathogenesis of Yersinia enterocolitica by Velasquez Almonacid, L.A., Tafuri, S., Dipineto, L., Matteoli, G., Fiorillo, E., Morte, R. Della, Fioretti, A., Menna, L.F., Staiano, N.

“…Connexin (Cx) channels are sites of cytoplasmic communication between contacting cells. Evidence indicates that the opening of hemichannels occurs under both…”
Get full text

Enteric glial cells: new players in mucosal defence against bacteria? by Matteoli, Gianluca

Get more information

DOP33 Single-cell analysis identifies pathological fibroblasts as a new therapeutic target to prevent intestinal fibrosis in Crohn’s disease by Ke, B J, Abdurahiman, S, Biscu, F, Verstockt, S, Verstockt, B, de Hertogh, G, Vermeire, S, Matteoli, G

“…Abstract Background Recurrent episodes of intestinal inflammation and tissue remodeling progressively result in fibro-stenosis and bowel obstruction in Crohn’s…”
Get full text

P008 Fibrostricturing Crohn’s disease is characterised by an imbalance in active eosinophils, Th1, Th2 and regulatory T cells by Jacobs, I, Ke, B J, Cremer, J, D’Hoore, A, Bislenghi, G, Matteoli, G, De Hertogh, G, Sabino, J, Ferrante, M, Vermeire, S, Breynaert, C, Vanuytsel, T, Verstockt, B

“…Abstract Background About one third of patients with Crohn’s disease (CD) develop strictures during their disease course requiring surgical resection. The…”
Get full text

OP32 TWIST1-mediated fibroblast activation protein (FAP)-expressing fibroblasts drives fibrosis in Crohn’s Disease by Ke, B J, Abdurahiman, S, Verstockt, B, Biscu, F, Zanella, G, Zouzaf, A, van Baarle, L, De Simone, V, Stakenborg, M, Santhosh, S, Verstockt, S, De Hertogh, G, Vermeire, S, Matteoli, G

“…Abstract Background Stricturing Crohn’s disease (CD) is a distinct clinical phenotype, characterised by the development of fibrotic strictures within the GI…”
Get full text

P099 Neutrophil extracellular traps enhance profibrotic activity of intestinal fibroblasts in Crohn's disease through TLR2/NF-kB pathway by Dragoni, G, Ke, B J, Picariello, L, Ceni, E, Mello, T, Verstockt, B, Abdurahiman, S, Biscu, F, Innocenti, T, De Hertogh, G, Martinod, K, Galli, A, Matteoli, G, Vermeire, S

“…Abstract Background Neutrophil extracellular traps (NETs) consist of DNA filaments and cytoplasmic protein granules, extruded by neutrophils after…”
Get full text

P082 The profibrogenic role of neutrophil extracellular traps in stenotic Crohn’s disease: a new antifibrotic target? by Dragoni, G, Ke, B J, Verstockt, B, Abdurahiman, S, Innocenti, T, Giudici, F, De Hertogh, G, Milla, M, Bagnoli, S, Picariello, L, Galli, A, Matteoli, G, Vermeire, S

“…Abstract Background Neutrophil extracellular traps (NETs) are structures constituted of DNA filaments and protein granules, extruded by neutrophils after…”
Get full text

P022 MET deletion in MRP8+ neutrophils is protective during DDS-induced colitis via Th17 pathway by Stakenborg, M., Meroni, E., Goverse, G., Matteoli, G.

Get full text

P032 Hepatocyte growth factor and MET in ulcerative colitis, novel drug targets impairing neutrophil recruitment? by Verstockt, B, Stakenborg, M, Wollants, W-J, Van Assche, G, Ferrante, M, Vermeire, S, Matteoli, G

“…Abstract Background Neutrophils are crucial in the maintenance of intestinal homeostasis and inflammation. However, during chronic inflammatory conditions,…”
Get full text

Early-life nicotine or cotinine exposure produces long-lasting sleep alterations and downregulation of hippocampal corticosteroid receptors in adult mice by Bastianini, Stefano, Lo Martire, Viviana, Alvente, Sara, Berteotti, Chiara, Matteoli, Gabriele, Rullo, Laura, Stamatakos, Serena, Silvani, Alessandro, Candeletti, Sanzio, Romualdi, Patrizia, Cohen, Gary, Zoccoli, Giovanna

“…Early-life exposure to environmental toxins like tobacco can permanently re-program body structure and function. Here, we investigated the long-term effects on…”
Get full text

P063 The immunological landscape of intestinal fibrosis in Crohn’s Disease by Jacobs, I, Creyns, B, Dragoni, G, Cremer, J, Bislenghi, G, D’Hoore, A, Ke, B J, Matteoli, G, De Hertogh, G, Ferrante, M, Joao, G S, Breynaert, C, Vermeire, S, Verstockt, B, Vanuytsel, T

“…Abstract Background Patients with Crohn’s disease (CD) often develop strictures, necessitating surgical intervention. The immune pathways expressed in the…”
Get full text