Search Results - "Mattei, Genevieve"

MG132‐induced progerin clearance is mediated by autophagy activation and splicing regulation by Harhouri, Karim, Navarro, Claire, Depetris, Danielle, Mattei, Marie‐Geneviève, Nissan, Xavier, Cau, Pierre, De Sandre‐Giovannoli, Annachiara, Lévy, Nicolas

“…Hutchinson–Gilford progeria syndrome (HGPS) is a lethal premature and accelerated aging disease caused by a de novo point mutation in LMNA encoding A‐type…”
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Hes1 is expressed in the second heart field and is required for outflow tract development by Rochais, Francesca, Dandonneau, Mathieu, Mesbah, Karim, Jarry, Thérèse, Mattei, Marie-Geneviève, Kelly, Robert G

“…Rapid growth of the embryonic heart occurs by addition of progenitor cells of the second heart field to the poles of the elongating heart tube. Failure or…”
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Neuromuscular defects and breathing disorders in a new mouse model of spinal muscular atrophy by Michaud, Magali, Arnoux, Thomas, Bielli, Serena, Durand, Estelle, Rotrou, Yann, Jablonka, Sibylle, Robert, Fabrice, Giraudon-Paoli, Marc, Riessland, Markus, Mattei, Marie-Geneviève, Andriambeloson, Emile, Wirth, Brunhilde, Sendtner, Michael, Gallego, Jorge, Pruss, Rebecca M, Bordet, Thierry

“…Abstract Spinal muscular atrophy (SMA) is caused by insufficient levels of the survival motor neuron (SMN) protein leading to muscle paralysis and respiratory…”
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A New Member of the Rho Family, Rnd1, Promotes Disassembly of Actin Filament Structures and Loss of Cell Adhesion by Nobes, Catherine D., Lauritzen, Inger, Mattei, Marie-Geneviève, Paris, Sonia, Hall, Alan, Chardin, Pierre

“…Members of the Rho GTPase family regulate the organization of the actin cytoskeleton in response to extracellular growth factors. We have identified three…”
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Identification and Characterization of a Novel Siglec, Siglec-7, Expressed by Human Natural Killer Cells and Monocytes by Nicoll, G, Ni, J, Liu, D, Klenerman, P, Munday, J, Dubock, S, Mattei, M G, Crocker, P R

“…We describe the characterization of sialic acid-binding Ig-like lectin-7 (siglec-7), a novel member of the siglec subgroup of the immunoglobulin superfamily. A…”
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Recurrent rearrangements in the proximal 15q11-q14 region: a new breakpoint cluster specific to unbalanced translocations by MIGNON-RAVIX, Cécile, DEPETRIS, Danielle, KROISEL, Peter M, MATTEI, Marie-Geneviève, LUCIANI, Judith J, CUOCO, Cristina, KRAJEWSKA-WALASEK, Malgorzata, MISSIRIAN, Chantal, COLLIGNON, Patrick, DELOBEL, Bruno, CROQUETTE, Marie-Francoise, MONCLA, Anne

“…Unbalanced translocations, that involve the proximal chromosome 15 long arm and the telomeric region of a partner chromosome, result in a karyotype of 45…”
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Identification and Characterization of a Novel Human Matrix Metalloproteinase with Unique Structural Characteristics, Chromosomal Location, and Tissue Distribution by Pendás, Alberto M., Knäuper, Vera, Puente, Xose S., Llano, Elena, Mattei, Marie-Genevieve, Apte, Suneel, Murphy, Gillian, López-Otín, Carlos

“…We have cloned a novel member of the matrix metalloproteinase (MMP) family of proteins from a human liver cDNA library. The isolated cDNA contains an open…”
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Identification and Characterization of a Widely Expressed Form of Adenylyl Cyclase by Premont, Richard T., Matsuoka, Isao, Mattei, Marie-Genevieve, Pouille, Yves, Defer, Nicole, Hanoune, Jacques

“…A novel mammalian adenylyl cyclase was identified by reverse transcription-polymerase chain reaction amplification using degenerate primers based on a…”
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A new Groucho TLE4 protein may regulate the repressive activity of Pax5 in human B lymphocytes by Milili, Michèle, Gauthier, Laurent, Veran, Julie, Mattei, Marie‐Geneviève, Schiff, Claudine

“…Summary During mouse B‐cell development, Pax5 is an essential transcription factor that acts as an activator of B‐cell‐specific genes and as a repressor of…”
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The del22q11.2 Candidate Gene Tbx1 Controls Regional Outflow Tract Identity and Coronary Artery Patterning by Théveniau-Ruissy, Magali, Dandonneau, Mathieu, Mesbah, Karim, Ghez, Olivier, Mattei, Marie-Geneviève, Miquerol, Lucile, Kelly, Robert G

“…TBX1, encoding a T-box containing transcription factor, is the major candidate gene for del22q11.2 or DiGeorge syndrome, characterized by craniofacial and…”
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TSPY, the candidate gonadoblastoma gene on the human Y chromosome, has a widely expressed homologue on the X - implications for Y chromosome evolution by Delbridge, Margaret L, Longepied, Guy, Depetris, Danielle, Mattei, Marie-Genevieve, Disteche, Christine M, Marshall Graves, Jennifer A, Mitchell, Michael J

“…TSPY, a candidate gene for a factor that promotes gonadoblastoma formation (GBY), is a testis-specific multicopy gene family in the male-specific region of the…”
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Ulip/CRMP proteins are recognized by autoantibodies in paraneoplastic neurological syndromes by Honnorat, Jérôme, Byk, Tamara, Kusters, Inca, Aguera, Michèle, Ricard, Damien, Rogemond, Véronique, Quach, Tam, Aunis, Dominique, Sobel, André, Mattei, Marie-Geneviève, Kolattukudy, Pappachan, Belin, Marie-Françoise, Antoine, Jean Christophe

“…Anti‐CV2 autoantibodies have recently been discovered in patients with paraneoplastic neurological diseases (PND). These disorders are associated with neuronal…”
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A mouse model for hereditary thyroid dysgenesis and cleft palate by DE FELICE, M, OVITT, C, MACCHIA, V, DI LAURO, R, BIFFALI, E, RODRIGUEZ-MALLON, A, ARRA, C, ANASTASSIADIS, K, MACCHIA, P. E, MATTEI, M.-G, MARIANO, A, SCHÖLER, H

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Cloning, chromosomal localization and identification of polymorphisms in the human thyroid transcription factor 2 gene (TITF2) by Macchia, Paolo E, Mattei, Marie-Geneviève, Lapi, Paola, Fenzi, Gianfranco, Di Lauro, Roberto

“…The human gene encoding the thyroid transcription factor 2 (TTF-2) was cloned and mapped to human chromosome 9q22. Three polymorphisms were identified in the…”
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Programmed cell death is affected in the novel mouse mutant Fused toes (Ft) by VAN DER HOEVEN, F, SCHIMMANG, T, VOLKMANN, A, MATTEI, M.-G, KYEWSKI, B, RÜTHER, U

“…We have identified a novel dominant mouse mutant that is characterised by fused toes on the fore limbs and a thymic hyperplasia, in heterozygous animals…”
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Identification, characterization and leucocyte expression of Siglec-10, a novel human sialic acid-binding receptor by Munday, J, Kerr, S, Ni, J, Cornish, A L, Zhang, J Q, Nicoll, G, Floyd, H, Mattei, M G, Moore, P, Liu, D, Crocker, P R

“…Here we characterize Siglec-10 as a new member of the Siglec family of sialic acid-binding Ig-like lectins. A full-length cDNA was isolated from a human spleen…”
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Genomic organization and the tissue distribution of alternatively spliced isoforms of the mouse Spatial gene by Irla, Magali, Puthier, Denis, Granjeaud, Samuel, Saade, Murielle, Victorero, Geneviève, Mattei, Marie-Geneviève, Nguyen, Catherine

“…The stromal component of the thymic microenvironment is critical for T lymphocyte generation. Thymocyte differentiation involves a cascade of coordinated…”
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A human interstitial telomere associates in vivo with specific TRF2 and TIN2 proteins by Mignon-Ravix, Cécile, Depetris, Danielle, Delobel, Bruno, Croquette, Marie-Françoise, Mattei, Marie-Geneviève

“…Mammalian telomeres are composed of long arrays of TTAGGG repeats that form a nucleoprotein complex which protects the chromosome ends. Human telomere function…”
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The chemokine TECK is expressed by thymic and intestinal epithelial cells and attracts double‐ and single‐positive thymocytes expressing the TECK receptor CCR9 by Wurbel, Marc‐André, Philippe, Jean‐Marc, Nguyen, Catherine, Victorero, Genevieve, Freeman, Tom, Wooding, Peter, Miazek, Arkadiusz, Mattei, Marie‐Geneviève, Malissen, Marie, Jordan, Bertrand R., Malissen, Bernard, Carrier, Alice, Naquet, Philippe

“…Chemokines are key regulators of migration in lymphoid tissues. In the thymus, maturing thymocytes move from the outer capsule to the inner medulla and thereby…”
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PML nuclear bodies are highly organised DNA-protein structures with a function in heterochromatin remodelling at the G2 phase by Luciani, J.J, Depetris, D, Usson, Y, Metzler-Guillemain, C, Mignon-Ravix, C, Mitchell, M.J, Megarbane, A, Sarda, P, Sirma, H, Moncla, A, Feunteun, J, Mattei, M.-G

“…We have recently demonstrated that heterochromatin HP1 proteins are aberrantly distributed in lymphocytes of patients with immunodeficiency, centromeric…”
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