Search Results - "Mattay, Venkata S"

common allele in the oxytocin receptor gene (OXTR) impacts prosocial temperament and human hypothalamic-limbic structure and function by Tost, Heike, Kolachana, Bhaskar, Hakimi, Shabnam, Lemaitre, Herve, Verchinski, Beth A, Mattay, Venkata S, Weinberger, Daniel R, Meyer-Lindenberg, Andreas

“…The evolutionarily highly conserved neuropeptide oxytocin is a key mediator of social and emotional behavior in mammals, including humans. A common variant…”
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Hierarchical Organization of Human Cortical Networks in Health and Schizophrenia by Bassett, Danielle S, Bullmore, Edward, Verchinski, Beth A, Mattay, Venkata S, Weinberger, Daniel R, Meyer-Lindenberg, Andreas

“…The complex organization of connectivity in the human brain is incompletely understood. Recently, topological measures based on graph theory have provided a…”
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Normal age-related brain morphometric changes: nonuniformity across cortical thickness, surface area and gray matter volume? by Lemaitre, Herve, Goldman, Aaron L, Sambataro, Fabio, Verchinski, Beth A, Meyer-Lindenberg, Andreas, Weinberger, Daniel R, Mattay, Venkata S

“…Abstract Normal aging is accompanied by global as well as regional structural changes. While these age-related changes in gray matter volume have been…”
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Age-related alterations in default mode network: Impact on working memory performance by Sambataro, Fabio, Murty, Vishnu P, Callicott, Joseph H, Tan, Hao-Yang, Das, Saumitra, Weinberger, Daniel R, Mattay, Venkata S

“…Abstract The default mode network (DMN) is a set of functionally connected brain regions which shows deactivation (task-induced deactivation, TID) during a…”
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Integrated DNA methylation and gene expression profiling across multiple brain regions implicate novel genes in Alzheimer’s disease by Semick, Stephen A., Bharadwaj, Rahul A., Collado-Torres, Leonardo, Tao, Ran, Shin, Joo Heon, Deep-Soboslay, Amy, Weiss, James R., Weinberger, Daniel R., Hyde, Thomas M., Kleinman, Joel E., Jaffe, Andrew E., Mattay, Venkata S.

“…Late-onset Alzheimer’s disease (AD) is a complex age-related neurodegenerative disorder that likely involves epigenetic factors. To better understand the…”
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Childhood urbanicity is associated with emotional episodic memory-related striatal function and common variation in NTRK2 by Zhang, Xiao, Zhang, Yuyanan, Yan, Hao, Yu, Hao, Zhang, Dai, Mattay, Venkata S, Tan, Hao Yang, Yue, Weihua

“…Childhoods in urban or rural environments may differentially affect the risk of neuropsychiatric disorders, possibly through memory processing and neural…”
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Seeking Optimal Region-Of-Interest (ROI) Single-Value Summary Measures for fMRI Studies in Imaging Genetics by Tong, Yunxia, Chen, Qiang, Nichols, Thomas E, Rasetti, Roberta, Callicott, Joseph H, Berman, Karen F, Weinberger, Daniel R, Mattay, Venkata S

“…A data-driven hypothesis-free genome-wide association (GWA) approach in imaging genetics studies allows screening the entire genome to discover novel genes…”
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Oxytocin Modulates Neural Circuitry for Social Cognition and Fear in Humans by Kirsch, Peter, Esslinger, Christine, Chen, Qiang, Mier, Daniela, Lis, Stefanie, Siddhanti, Sarina, Gruppe, Harald, Mattay, Venkata S, Gallhofer, Bernd, Meyer-Lindenberg, Andreas

“…In non-human mammals, the neuropeptide oxytocin is a key mediator of complex emotional and social behaviors, including attachment, social recognition, and…”
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A validated network of effective amygdala connectivity by Stein, Jason L., Wiedholz, Lisa M., Bassett, Danielle S., Weinberger, Daniel R., Zink, Caroline F., Mattay, Venkata S., Meyer-Lindenberg, Andreas

“…Regulatory interactions with the amygdala are thought to be critical for emotional processing in the extended limbic system. Structural equation modeling (path…”
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5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism for depression by Weinberger, Daniel R, Pezawas, Lukas, Meyer-Lindenberg, Andreas, Drabant, Emily M, Verchinski, Beth A, Munoz, Karen E, Kolachana, Bhaskar S, Egan, Michael F, Mattay, Venkata S, Hariri, Ahmad R

“…Carriers of the short allele of a functional 5' promoter polymorphism of the serotonin transporter gene have increased anxiety-related temperamental traits,…”
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A generative-discriminative framework that integrates imaging, genetic, and diagnosis into coupled low dimensional space by Ghosal, Sayan, Chen, Qiang, Pergola, Giulio, Goldman, Aaron L., Ulrich, William, Berman, Karen F., Blasi, Giuseppe, Fazio, Leonardo, Rampino, Antonio, Bertolino, Alessandro, Weinberger, Daniel R., Mattay, Venkata S., Venkataraman, Archana

“…We propose a novel optimization framework that integrates imaging and genetics data for simultaneous biomarker identification and disease classification. The…”
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Neurophysiological correlates of age-related changes in working memory capacity by Mattay, Venkata. S., Fera, Francesco, Tessitore, Alessandro, Hariri, Ahmad R., Berman, Karen F., Das, Saumitra, Meyer-Lindenberg, Andreas, Goldberg, Terry E., Callicott, Joseph H., Weinberger, Daniel R.

“…Cognitive abilities such as working memory (WM) capacity decrease with age. To determine the neurophysiological correlates of age-related reduction in working…”
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The Brain-Derived Neurotrophic Factor val66met Polymorphism and Variation in Human Cortical Morphology by Pezawas, Lukas, Verchinski, Beth A, Mattay, Venkata S, Callicott, Joseph H, Kolachana, Bhaskar S, Straub, Richard E, Egan, Michael F, Meyer-Lindenberg, Andreas, Weinberger, Daniel R

“…A variation in the BDNF gene (val66met) affects the function of BDNF in neurons, predicts variation in human memory, and is associated with several…”
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Neocortical modulation of the amygdala response to fearful stimuli by Hariri, Ahmad R, Mattay, Venkata S, Tessitore, Alessandro, Fera, Francesco, Weinberger, Daniel R

“…The cortical circuitry involved in conscious cognitive processes and the subcortical circuitry involved in fear responses have been extensively studied with…”
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Complexity of Prefrontal Cortical Dysfunction in Schizophrenia: More Than Up or Down by Callicott, Joseph H., Mattay, Venkata S., Verchinski, Beth A., Marenco, Stefano, Egan, Michael F., Weinberger, Daniel R.

“…OBJECTIVE: Numerous neuroimaging studies have examined the function of the dorsolateral prefrontal cortex in schizophrenia; although abnormalities usually are…”
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The Amygdala Response to Emotional Stimuli: A Comparison of Faces and Scenes by Hariri, Ahmad R., Tessitore, Alessandro, Mattay, Venkata S., Fera, Francesco, Weinberger, Daniel R.

“…Asa central fear processor of the brain, the amygdala initiates a cascade of critical physiological and behavioral responses. Neuroimaging studies have shown…”
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Serotonin Transporter Genetic Variation and the Response of the Human Amygdala by Hariri, Ahmad R., Mattay, Venkata S., Tessitore, Alessandro, Kolachana, Bhaskar, Fera, Francesco, Goldman, David, Egan, Michael F., Weinberger, Daniel R.

“…A functional polymorphism in the promoter region of the human serotonin transporter gene (SLC6A4) has been associated with several dimensions of neuroticism…”
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Neanderthal-Derived Genetic Variation Shapes Modern Human Cranium and Brain by Gregory, Michael D., Kippenhan, J. Shane, Eisenberg, Daniel P., Kohn, Philip D., Dickinson, Dwight, Mattay, Venkata S., Chen, Qiang, Weinberger, Daniel R., Saad, Ziad S., Berman, Karen F.

“…Before their disappearance from the fossil record approximately 40,000 years ago, Neanderthals, the ancient hominin lineage most closely related to modern…”
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Impact of interacting functional variants in COMT on regional gray matter volume in human brain by Honea, Robyn, Verchinski, Beth A., Pezawas, Lukas, Kolachana, Bhaskar S., Callicott, Joseph H., Mattay, Venkata S., Weinberger, Daniel R., Meyer-Lindenberg, Andreas

“…Functional variants in the catechol- O-methyltransferase ( COMT) gene have been shown to impact cognitive function, cortical physiology and risk for…”
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Variation in DISC1 Affects Hippocampal Structure and Function and Increases Risk for Schizophrenia by Callicott, Joseph H., Straub, Richard E., Pezawas, Lukas, Egan, Michael F., Mattay, Venkata S., Hariri, Ahmad R., Verchinski, Beth A., Meyer-Lindenberg, Andreas, Balkissoon, Rishi, Kolachana, Bhaskar, Goldberg, Terry E., Weinberger, Daniel R., Scolnick, Edward M.

“…Disrupted-in-schizophrenia 1 (DISC1) is a promising schizophrenia candidate gene expressed predominantly within the hippocampus. We typed 12 single-nucleotide…”
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