Search Results - "Matt, Lucas"

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    Perampanel inhibition of AMPA receptor currents in cultured hippocampal neurons by Chen, Chao-Yin, Matt, Lucas, Hell, Johannes Wilhelm, Rogawski, Michael A

    Published in PloS one (17-09-2014)
    “…Perampanel is an aryl substituted 2-pyridone AMPA receptor antagonist that was recently approved as a treatment for epilepsy. The drug potently inhibits AMPA…”
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    Journal Article
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    Role of Palmitoylation of Postsynaptic Proteins in Promoting Synaptic Plasticity by Matt, Lucas, Kim, Karam, Chowdhury, Dhrubajyoti, Hell, Johannes W

    Published in Frontiers in molecular neuroscience (31-01-2019)
    “…Many postsynaptic proteins undergo palmitoylation, the reversible attachment of the fatty acid palmitate to cysteine residues, which influences trafficking,…”
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    α-Actinin Anchors PSD-95 at Postsynaptic Sites by Matt, Lucas, Kim, Karam, Hergarden, Anne C., Patriarchi, Tommaso, Malik, Zulfiqar A., Park, Deborah K., Chowdhury, Dhrubajyoti, Buonarati, Olivia R., Henderson, Peter B., Gökçek Saraç, Çiğdem, Zhang, Yonghong, Mohapatra, Durga, Horne, Mary C., Ames, James B., Hell, Johannes W.

    Published in Neuron (Cambridge, Mass.) (07-03-2018)
    “…Despite the central role PSD-95 plays in anchoring postsynaptic AMPARs, how PSD-95 itself is tethered to postsynaptic sites is not well understood. Here we…”
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    The Na+-activated K+ channel Slack contributes to synaptic development and plasticity by Matt, Lucas, Pham, Thomas, Skrabak, David, Hoffmann, Felix, Eckert, Philipp, Yin, Jiaqi, Gisevius, Miriam, Ehinger, Rebekka, Bausch, Anne, Ueffing, Marius, Boldt, Karsten, Ruth, Peter, Lukowski, Robert

    “…Human mutations of the Na + -activated K + channel Slack ( KCNT1 ) are associated with epilepsy and intellectual disability. Accordingly, Slack knockout mice (…”
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    β2 Adrenergic Receptor, Protein Kinase A (PKA) and c-Jun N-terminal Kinase (JNK) Signaling Pathways Mediate Tau Pathology in Alzheimer Disease Models by Wang, Dayong, Fu, Qin, Zhou, Yuan, Xu, Bing, Shi, Qian, Igwe, Benedict, Matt, Lucas, Hell, Johannes W., Wisely, Elena V., Oddo, Salvatore, Xiang, Yang K.

    Published in The Journal of biological chemistry (12-04-2013)
    “…Alzheimer disease (AD) is characterized by neurodegeneration marked by loss of synapses and spines associated with hyperphosphorylation of tau protein…”
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    Slack K+ channels limit kainic acid-induced seizure severity in mice by modulating neuronal excitability and firing by Skrabak, David, Bischof, Helmut, Pham, Thomas, Ruth, Peter, Ehinger, Rebekka, Matt, Lucas, Lukowski, Robert

    Published in Communications biology (11-10-2023)
    “…Mutations of the Na + -activated K + channel Slack ( KCNT1 ) are associated with terrible epilepsy syndromes that already begin in infancy. Here we report…”
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    Potassium ions promote hexokinase-II dependent glycolysis by Bischof, Helmut, Burgstaller, Sandra, Springer, Anna, Matt, Lucas, Rauter, Thomas, Bachkönig, Olaf A., Schmidt, Tony, Groschner, Klaus, Schindl, Rainer, Madl, Tobias, Plesnila, Nikolaus, Lukowski, Robert, Graier, Wolfgang F., Malli, Roland

    Published in iScience (23-04-2021)
    “…High expression levels of mitochondria-associated hexokinase-II (HKII) represent a hallmark of metabolically highly active cells such as fast proliferating…”
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    Futurology by Lucas, Matt

    Published in ITNow (01-12-2024)
    “…Abstract Matt Lucas FBCS CITP dives into the potential and pitfalls of the nondeterministic nature of quantum computing…”
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    Futurology by Lucas, Matt

    Published in ITNow (01-09-2024)
    “…Abstract Matt Lucas FBCS writes on the evolving role of AI in the future of defence, the risks of innovation outpacing legislation, and how working with…”
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    Futurology by Lucas, Matt

    Published in ITNow (20-05-2024)
    “…Abstract Matt Lucas FBCS gives some personal predictions about the use of AI in the creative industry…”
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    Futurology by Lucas, Matt

    Published in ITNow (15-02-2024)
    “…Abstract Matt Lucas FBCS explores the potential afforded by technology to create more transparent and robust food supply chains, improving sustainability while…”
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    Futurology by Lucas, Matt

    Published in ITNow (23-11-2023)
    “…Abstract Matt Lucas, Senior Product Manager at IBM, and Isabel Fischer, Associate Professor of Information Systems at Warwick Business School, consider the…”
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    Futurology by Lucas, Matt

    Published in ITNow (23-08-2023)
    “…Abstract Measuring software engineering efficiency has always been an impossible task. Matt Lucas FBCS reflects on the expansion of environmental, social and…”
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