Search Results - "Matt, Lucas"
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CROSSLINGUISTIC INFLUENCE AND SECOND LANGUAGE LEARNING, KevinMcManus, Routledge. ISBN 978‐03673‐57856 (hardcover), 978‐03673‐57825 (paperback), 978‐04293‐41663 (e‐book). Price USD 128.00 (hardcover), 39.96 (paperback or e‐book). x + 163 pages
Published in TESOL journal (01-06-2023)Get full text
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Perampanel inhibition of AMPA receptor currents in cultured hippocampal neurons
Published in PloS one (17-09-2014)“…Perampanel is an aryl substituted 2-pyridone AMPA receptor antagonist that was recently approved as a treatment for epilepsy. The drug potently inhibits AMPA…”
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Role of Palmitoylation of Postsynaptic Proteins in Promoting Synaptic Plasticity
Published in Frontiers in molecular neuroscience (31-01-2019)“…Many postsynaptic proteins undergo palmitoylation, the reversible attachment of the fatty acid palmitate to cysteine residues, which influences trafficking,…”
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α-Actinin Anchors PSD-95 at Postsynaptic Sites
Published in Neuron (Cambridge, Mass.) (07-03-2018)“…Despite the central role PSD-95 plays in anchoring postsynaptic AMPARs, how PSD-95 itself is tethered to postsynaptic sites is not well understood. Here we…”
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The Na+-activated K+ channel Slack contributes to synaptic development and plasticity
Published in Cellular and molecular life sciences : CMLS (01-12-2021)“…Human mutations of the Na + -activated K + channel Slack ( KCNT1 ) are associated with epilepsy and intellectual disability. Accordingly, Slack knockout mice (…”
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mitoBKCa is functionally expressed in murine and human breast cancer cells and potentially contributes to metabolic reprogramming
Published in eLife (29-05-2024)“…Alterations in the function of K + channels such as the voltage- and Ca 2+ -activated K + channel of large conductance (BK Ca ) reportedly promote breast…”
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β2 Adrenergic Receptor, Protein Kinase A (PKA) and c-Jun N-terminal Kinase (JNK) Signaling Pathways Mediate Tau Pathology in Alzheimer Disease Models
Published in The Journal of biological chemistry (12-04-2013)“…Alzheimer disease (AD) is characterized by neurodegeneration marked by loss of synapses and spines associated with hyperphosphorylation of tau protein…”
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Competition between α-actinin and Ca2+-Calmodulin Controls Surface Retention of the L-type Ca2+ Channel CaV1.2
Published in Neuron (Cambridge, Mass.) (08-05-2013)“…Regulation of neuronal excitability and cardiac excitation-contraction coupling requires the proper localization of L-type Ca2+ channels. We show that the…”
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Slack K+ channels limit kainic acid-induced seizure severity in mice by modulating neuronal excitability and firing
Published in Communications biology (11-10-2023)“…Mutations of the Na + -activated K + channel Slack ( KCNT1 ) are associated with terrible epilepsy syndromes that already begin in infancy. Here we report…”
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SynDIG4/Prrt1 Is Required for Excitatory Synapse Development and Plasticity Underlying Cognitive Function
Published in Cell reports (Cambridge) (27-02-2018)“…Altering AMPA receptor (AMPAR) content at synapses is a key mechanism underlying the regulation of synaptic strength during learning and memory. Previous work…”
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Potassium ions promote hexokinase-II dependent glycolysis
Published in iScience (23-04-2021)“…High expression levels of mitochondria-associated hexokinase-II (HKII) represent a hallmark of metabolically highly active cells such as fast proliferating…”
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Visualizing BDNF Transcript Usage During Sound-Induced Memory Linked Plasticity
Published in Frontiers in molecular neuroscience (31-07-2018)“…Activity-dependent BDNF (brain-derived neurotrophic factor) expression is hypothesized to be a cue for the context-specificity of memory formation. So far,…”
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BDNF-Live-Exon-Visualization (BLEV) Allows Differential Detection of BDNF Transcripts in vitro and in vivo
Published in Frontiers in molecular neuroscience (27-09-2018)“…exon-IV and exon-VI transcripts are driven by neuronal activity and are involved in pathologies related to sleep, fear or memory disorders. However, how their…”
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Potassium ions promote hexokinase-II dependent glycolysis
Published in iScience (21-05-2021)Get full text
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Futurology
Published in ITNow (01-12-2024)“…Abstract Matt Lucas FBCS CITP dives into the potential and pitfalls of the nondeterministic nature of quantum computing…”
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Futurology
Published in ITNow (01-09-2024)“…Abstract Matt Lucas FBCS writes on the evolving role of AI in the future of defence, the risks of innovation outpacing legislation, and how working with…”
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Futurology
Published in ITNow (20-05-2024)“…Abstract Matt Lucas FBCS gives some personal predictions about the use of AI in the creative industry…”
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Futurology
Published in ITNow (15-02-2024)“…Abstract Matt Lucas FBCS explores the potential afforded by technology to create more transparent and robust food supply chains, improving sustainability while…”
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Futurology
Published in ITNow (23-11-2023)“…Abstract Matt Lucas, Senior Product Manager at IBM, and Isabel Fischer, Associate Professor of Information Systems at Warwick Business School, consider the…”
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Futurology
Published in ITNow (23-08-2023)“…Abstract Measuring software engineering efficiency has always been an impossible task. Matt Lucas FBCS reflects on the expansion of environmental, social and…”
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