Search Results - "Matsuzaki, Toshio"

HLA-A24 Increases the Risk of HTLV-1-Associated Myelopathy despite Reducing HTLV-1 Proviral Load by Tanaka, Masakazu, Takenouchi, Norihiro, Arishima, Shiho, Matsuzaki, Toshio, Nozuma, Satoshi, Matsuura, Eiji, Takashima, Hiroshi, Kubota, Ryuji

“…Increased human T-cell leukemia virus type 1 (HTLV-1) proviral load (PVL) is a significant risk factor for HTLV-1-associated myelopathy/tropical spastic…”
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Geographic characteristics of HTLV-1 molecular subgroups and genetic substitutions in East Asia: Insights from complete genome sequencing of HTLV-1 strains isolated in Taiwan and Japan by Nozuma, Satoshi, Yoshimura, Akiko, Pai, Shun-Chung, Chen, Hung-Jen, Matsuura, Eiji, Tanaka, Masakazu, Kodama, Daisuke, Dozono, Mika, Matsuzaki, Toshio, Takashima, Hiroshi, Yang, Ya-Chien, Kubota, Ryuji

“…Although Japan is a major endemic area for human T-lymphotropic virus type 1 (HTLV-1) and the virus has been well-studied in this region, there is limited…”
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In vivo expression of the HBZ gene of HTLV-1 correlates with proviral load, inflammatory markers and disease severity in HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) by Saito, Mineki, Matsuzaki, Toshio, Satou, Yorifumi, Yasunaga, Jun-Ichirou, Saito, Kousuke, Arimura, Kimiyoshi, Matsuoka, Masao, Ohara, Yoshiro

“…Recently, human T-cell leukemia virus type 1 (HTLV-1) basic leucine zipper factor (HBZ), encoded from a minus strand mRNA was discovered and was suggested to…”
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Effects of host restriction factors and the HTLV-1 subtype on susceptibility to HTLV-1-associated myelopathy/tropical spastic paraparesis by Nozuma, Satoshi, Matsuura, Eiji, Kodama, Daisuke, Tashiro, Yuichi, Matsuzaki, Toshio, Kubota, Ryuji, Izumo, Shuji, Takashima, Hiroshi

“…Although human T-lymphotropic virus type 1 (HTLV-1) infection is a prerequisite for the development of HTLV-1-associated myelopathy/tropical spastic…”
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Inhibition of ABL1 tyrosine kinase reduces HTLV-1 proviral loads in peripheral blood mononuclear cells from patients with HTLV-1-associated myelopathy/tropical spastic paraparesis by Kodama, Daisuke, Tanaka, Masakazu, Matsuzaki, Toshio, Izumo, Kimiko, Nakano, Nobuaki, Matsuura, Eiji, Saito, Mineki, Nagai, Masahiro, Horiuchi, Masahisa, Utsunomiya, Atae, Takashima, Hiroshi, Kubota, Ryuji, Izumo, Shuji

“…Human T-cell leukemia virus type 1 (HTLV-1) causes incurable adult T-cell leukemia and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP)…”
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Familial clusters of HTLV-1-associated myelopathy/tropical spastic paraparesis by Nozuma, Satoshi, Matsuura, Eiji, Matsuzaki, Toshio, Watanabe, Osamu, Kubota, Ryuji, Izumo, Shuji, Takashima, Hiroshi

“…HTLV-1 proviral loads (PVLs) and some genetic factors are reported to be associated with the development of HTLV-1-associated myelopathy/tropical spastic…”
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The CC chemokine ligand (CCL) 1, upregulated by the viral transactivator Tax, can be downregulated by minocycline: possible implications for long-term treatment of HTLV-1-associated myelopathy/tropical spastic paraparesis by Saito, Mineki, Sejima, Hiroe, Naito, Tadasuke, Ushirogawa, Hiroshi, Matsuzaki, Toshio, Matsuura, Eiji, Tanaka, Yuetsu, Nakamura, Tatsufumi, Takashima, Hiroshi

“…Chemokine (C-C motif) ligand 1 (CCL1) is produced by activated monocytes/ macrophages and T-lymphocytes, and acts as a potent attractant for Th2 cells and a…”
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Correction: Familial Clusters of HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis by Nozuma, Satoshi, Matsuura, Eiji, Matsuzaki, Toshio, Watanabe, Osamu, Kubota, Ryuji, Izumo, Shuji, Takashima, Hiroshi

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Identification and tracking of HTLV-1-infected T cell clones in virus-associated neurologic disease by Nozuma, Satoshi, Matsuura, Eiji, Tanaka, Masakazu, Kodama, Daisuke, Matsuzaki, Toshio, Yoshimura, Akiko, Sakiyama, Yusuke, Nakahata, Shingo, Morishita, Kazuhiro, Enose-Akahata, Yoshimi, Jacoboson, Steven, Kubota, Ryuji, Takashima, Hiroshi

“…Human T lymphotropic virus type 1-assoicated (HTLV-1-associated) myelopathy/tropical spastic paraparesis (HAM/TSP) is a neuroinflammatory disease caused by the…”
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Efficacy of l‐Arginine treatment in patients with HTLV‐1‐associated neurological disease by Nozuma, Satoshi, Matsuura, Eiji, Tashiro, Yuichi, Nagata, Ryusei, Ando, Masahiro, Hiramatsu, Yu, Higuchi, Yujiro, Sakiyama, Yusuke, Hashiguchi, Akihiro, Michizono, Kumiko, Higashi, Keiko, Matsuzaki, Toshio, Kodama, Daisuke, Tanaka, Masakazu, Yamano, Yoshihisa, Moritoyo, Takashi, Kubota, Ryuji, Takashima, Hiroshi

“…Objective HTLV‐1 infection causes HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP), resulting in loss of motor function. In this Phase 2…”
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Prevalence of plasma autoantibody against cancer testis antigen NY-ESO-1 in HTLV-1 infected individuals with different clinical status by Shiohama, Yasuo, Naito, Tadasuke, Matsuzaki, Toshio, Tanaka, Reiko, Tomoyose, Takeaki, Takashima, Hiroshi, Fukushima, Takuya, Tanaka, Yuetsu, Saito, Mineki

“…Detection of specific immune responses against cancer/testis antigen NY-ESO-1 was recently reported in patients with adult T-cell leukemia/lymphoma (ATL) and…”
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Early diagnosis of HTLV-1-associated myelopathy (HAM/TSP) in HTLV-1 carrier clinic by Matsuzaki, Toshio, Kubota, Ryuji, Takashima, Hiroshi, Izumo, Shuji

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Recent epidemiologic trends of HAM/TSP in Japan by Matsuzaki, Toshio, Kodama, Tomoko, Kubota, Ryuji, Izumo, Shuji

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HLA-A24-restricted HTLV-I-specific CTL response reduces the HTLV-I proviral load but the HLA increases the risk of HAM/TSP by Kubota, Ryuji, Takenouchi, Norihiro, Matsuzaki, Toshio, Takashima, Hiroshi, Izumo, Shuji

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Successful development of novel monoclonal antibodies against HTLV-1 bZIP factor and their applications in studying the pathogenesis of HAM/TSP by Saito, Mineki, Tanaka, Reiko, Kodama, Akira, Matsuzaki, Toshio, Suehara, Masahito, Tanaka, Yuetsu

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A prospective uncontrolled trial of fermented milk drink containing viable Lactobacillus casei strain Shirota in the treatment of HTLV-1 associated myelopathy/tropical spastic paraparesis by Matsuzaki, Toshio, Saito, Mineki, Usuku, Koichiro, Nose, Hirohisa, Izumo, Shuji, Arimura, Kimiyoshi, Osame, Mitsuhiro

“…Ten patients with human T-cell lymphotropic virus type-1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) were treated in an uncontrolled…”
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HTLV-I proviral load correlates with progression of motor disability in HAM/TSP: Analysis of 239 HAM/TSP patients including 64 patients followed up for 10 years by Toshio Matsuzaki, Masanori Nakagawa, Masahiro Nagai, Koichiro Usuku, Itsuro Higuchi, Kimiyoshi Arimura, Hiroaki Kubota, Shuji Izumo, Suminori Akiba, Mitsuhiro Osame

“…To clarify clinical and laboratory findings that may be related to the pathomechanism of HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP),…”
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Reduced Tim-3 expression on HTLV-I Tax-specific cytotoxic T lymphocytes in HTLV-I infection by Abdelbary, Nashwa H, Abdullah, Hazem M, Matsuzaki, Toshio, Hayashi, Daisuke, Tanaka, Yuetsu, Takashima, Hiroshi, Izumo, Shuji, Kubota, Ryuji

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A new type of hereditary motor and sensory neuropathy linked to chromosome 3 by Takashima, H, Nakagawa, M, Nakahara, K, Suehara, M, Matsuzaki, T, Higuchi, I, Higa, H, Arimura, K, Iwamasa, T, Izumo, S, Osame, M

“…We report the clinical, pathological, and genetic findings of 23 patients in 8 families with hereditary motor and sensory neuropathy (proximal dominant form)…”
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Anti-Human T-Cell Leukemia Virus Type 1 (HTLV-1) Antibody Assays in Cerebrospinal Fluid for the Diagnosis of HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis by Kodama, Daisuke, Tanaka, Masakazu, Matsuzaki, Toshio, Nozuma, Satoshi, Matsuura, Eiji, Takashima, Hiroshi, Izumo, Shuji, Kubota, Ryuji

“…The anti-human T-cell leukemia virus type 1 (HTLV-1) antibody assay in common use has changed from the particle agglutination (PA) method to chemiluminescent…”
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