Search Results - "Matsuura, R"

Ketones and the Heart: Metabolic Principles and Therapeutic Implications by Matsuura, Timothy R, Puchalska, Patrycja, Crawford, Peter A, Kelly, Daniel P

“…The ketone bodies beta-hydroxybutyrate and acetoacetate are hepatically produced metabolites catabolized in extrahepatic organs. Ketone bodies are a critical…”
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A Critical Role for Estrogen-Related Receptor Signaling in Cardiac Maturation by Sakamoto, Tomoya, Matsuura, Timothy R., Wan, Shibiao, Ryba, David M., Kim, J`unil, Won, Kyoung Jae, Lai, Ling, Petucci, Christopher, Petrenko, Nataliya, Musunuru, Kiran, Vega, Rick B., Kelly, Daniel P.

“…The heart undergoes dramatic developmental changes during the prenatal to postnatal transition, including maturation of cardiac myocyte energy metabolic and…”
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The failing heart utilizes 3-hydroxybutyrate as a metabolic stress defense by Horton, Julie L, Davidson, Michael T, Kurishima, Clara, Vega, Rick B, Powers, Jeffery C, Matsuura, Timothy R, Petucci, Christopher, Lewandowski, E Douglas, Crawford, Peter A, Muoio, Deborah M, Recchia, Fabio A, Kelly, Daniel P

“…Evidence has emerged that the failing heart increases utilization of ketone bodies. We sought to determine whether this fuel shift is adaptive. Mice rendered…”
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Early Effects of Prolonged Cardiac Arrest and Ischemic Postconditioning during Cardiopulmonary Resuscitation on Cardiac and Brain Mitochondrial Function in Pigs by Matsuura, Timothy R., BA, Bartos, Jason A., MD, PhD, Tsangaris, Adamantios, MD, Shekar, Kadambari Chandra, MS, Olson, Matthew D., MD, Riess, Matthias L., MD, PhD, Bienengraeber, Martin, PhD, Aufderheide, Tom P., MD, MS, Neumar, Robert W., MD, PhD, Rees, Jennifer N., PhD, McKnite, Scott H., BS, Dikalova, Anna E., PhD, Dikalov, Sergey I., PhD, Douglas, Hunter F., BS, Yannopoulos, Demetris, MD

“…Abstract Background Out-of-hospital cardiac arrest (CA) is a prevalent medical crisis resulting in severe injury to the heart and brain and an overall survival…”
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Successful Heart Transplantation After Desensitization in a Patient With Extremely High Panel-Reactive Antibody Levels and Pretransplant Donor-Specific Antibody: A Case Report by Nakamura, Y., Yoshioka, D., Miyagawa, S., Yoshikawa, Y., Hata, H., Matsuura, R., Toda, K., Sawa, Y.

“…Elevated panel-reactive antibody (PRA) levels serve as a significant risk factor for allograft survival and episodes of rejection after heart transplantation…”
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Effects of resistive load on performance and surface EMG activity during repeated cycling sprints on a non-isokinetic cycle ergometer by Matsuura, R, Arimitsu, T, Yunoki, T, Yano, T

“…To determine the effects of resistive load on performance and surface electromyogram (SEMG) activity during repeated cycling sprints (RCS) on a non-isokinetic…”
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Immunological Response of Pigs to Human Cells, Including Issues Such as the Production of Natural Antibodies in Newborns by Sakai, R., Watanabe, M., Maeda, A., Lo, P.C., Wang, H.T., Matsuura, R., Kodama, T., Eguchi, H., Ueno, T., Inoue, R., Nagashima, H., Okuyama, H., Miyagawa, S.

“…Pigs have recently become very popular for use not only in xenotransplantation field, but in regeneration studies as well, sometimes with pigs being used as…”
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Expression of a Synthetic Gene of CTDM by Transgenic Animals by Sakai, R, Maeda, A, Matsuura, R, Eguchi, H, Lo, P, Hasuwa, H, Ikawa, M, Nakahata, K, Zenitani, M, Yamamichi, T, Umeda, S, Okuyama, H, Miyagawa, S

“…Abstract Background The purpose of this study was to produce molecules that can precisely regulate the complement and coagulation system and to assess the…”
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Knockout of Cytidine Monophospho- N -Acetylneuraminic Acid (CMP-NeuAc) Hydroxylase From Porcine Endothelial Cells by a CRISPR System by Sakai, R, Esaki, Y, Hasuwa, H, Ikawa, M, Lo, P, Matsuura, R, Nakahata, K, Zenitani, M, Asada, M, Maeda, A, Eguchi, H, Okuyama, H, Miyagawa, S

“…Abstract Background We attempted to knock out the expression of Hanganutziu-Deicher (H-D) antigens through the use of a CRISPR (clustered regulatory…”
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Liver Failure From Ultra-Short Bowel Syndrome on the Intestinal Transplant Waiting List: A Retrospective Study by Noguchi, Y, Ueno, T, Matsuura, R, Kodama, T, Deguchi, K, Umeda, S, Yamamichi, T, Nakahata, K, Zenitani, M, Takama, Y, Yamanaka, H, Tazuke, Y, Okuyama, H

“…Abstract Background Patients with intestinal failure (IF) are candidates for intestinal transplantation (ITx). In Japan, these patients have few opportunities…”
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Intracoronary Poloxamer 188 Prevents Reperfusion Injury in a Porcine Model of ST-Segment Elevation Myocardial Infarction by Bartos, Jason A., MD, PhD, Matsuura, Timothy R., BA, Tsangaris, Adamantios, MD, Olson, Matthew, MD, McKnite, Scott H., BS, Rees, Jennifer N., PhD, Haman, Karen, PhD, Shekar, Kadambari Chandra, MS, Riess, Matthias L., MD, PhD, Bates, Frank S., ScD, Metzger, Joseph M., PhD, Yannopoulos, Demetris, MD

“…Summary Poloxamer 188 (P188) is a nonionic triblock copolymer believed to prevent cellular injury after ischemia and reperfusion. This study compared…”
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Studies of Pig Complement: Measurement of Pig CH50, ACH50, and Components by Sakai, R, Kitano, E, Hatanaka, M, Lo, P, Matsuura, R, Deguchi, K, Eguchi, H, Maeda, A, Watanabe, M, Matsunari, H, Nagashima, H, Okuyama, H, Miyagawa, S

“…Abstract Background On the basis of a comparison of the hemolytic complement titer in pigs with that in humans, the complement system of pigs was investigated…”
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HLA-G1, but Not HLA-G3, Suppresses Human Monocyte/Macrophage-mediated Swine Endothelial Cell Lysis by Eguchi, H, Maeda, A, Lo, P.C, Matsuura, R, Esquivel, E.L, Asada, M, Sakai, R, Nakahata, K, Yamamichi, T, Umeda, S, Deguchi, K, Ueno, T, Okuyama, H, Miyagawa, S

“…Abstract The inhibitory function of HLA-G1, a class Ib molecule, on monocyte/macrophage−mediated cytotoxicity was examined. The expression of inhibitory…”
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Disseminated Metastatic Tissue Calcification After Orthotopic Liver Transplantation: A Case Report by Deguchi, K, Ueno, T, Matsuura, R, Yamanaka, H, Nara, K, Uehara, S, Tazuke, Y, Bessho, K, Okuyama, H

“…Abstract Background Hypercalcemia has been observed in patients after liver transplantation. However, it is rare that the hypercalcemia induced disseminated…”
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Supplemental Analysis for N -linked Sugars in Adult Pig Islets by Eguchi, H, Kawamura, T, Kashiyama, N, Matsuura, R, Sakai, R, Nakahata, K, Lo, P.-C, Asada, M, Maeda, A, Goto, M, Toyoda, M, Okuyama, H, Miyagawa, S

“…Abstract The pig pancreas is considered to be one of the most suitable sources of islets for clinical xenotransplantation. However, after producing…”
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Development of visual cells in the Pacific bluefin tuna Thunnus orientalis by Matsuura, R, Sawada, Y, Ishibashi, Y

“…The development of rod and cone photoreceptor cells was investigated in the retinas of Pacific bluefin tuna larvae and juveniles, using RET-P1 monoclonal…”
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PO073 EFFICACY OF THE INTENSIVE “ACTIVITY” MANAGEMENT COUPLED WITH “THE PATIENT DIARY” IN THE DEVELOPMENT OF DIABETIC NEPHROPATHY by Kubooka, Y, Miuchi, M, Shingaki, H, Matsuura, R, Futagami, R, Kawano, H, Ura, H, Orino, Y, Kawai, Y, Araki, K, Mitsuno, K, Katsuno, T, Miyagawa, J.-i, Namba, M

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Fueling Cardiac Hypertrophy by Matsuura, Timothy R., Leone, Teresa C., Kelly, Daniel P.

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Ketone Ester Treatment Improves Cardiac Function and Reduces Pathologic Remodeling in Preclinical Models of Heart Failure by Yurista, Salva R., Matsuura, Timothy R., Silljé, Herman H.W., Nijholt, Kirsten T., McDaid, Kendra S., Shewale, Swapnil V., Leone, Teresa C., Newman, John C., Verdin, Eric, van Veldhuisen, Dirk J., de Boer, Rudolf A., Kelly, Daniel P., Westenbrink, B. Daan

“…Accumulating evidence suggests that the failing heart reprograms fuel metabolism toward increased utilization of ketone bodies and that increasing cardiac…”
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Effects of heat exposure in the absence of hyperthermia on power output during repeated cycling sprints by Matsuura, R, Arimitsu, T, Yunoki, T, Kimura, T, Yamanaka, R, Yano, T

“…The aim of this study was to investigate the effects of heat exposure in the absence of hyperthermia on power output during repeated cycling sprints. Seven…”
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