Search Results - "Matsusaka, S"

Triboelectric charging of powders: A review by Matsusaka, S., Maruyama, H., Matsuyama, T., Ghadiri, M.

“…Particles are often electrostatically charged by frictional contact during powder-handling operations. This phenomenon is called ‘triboelectric charging’ or…”
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Impact of genetic variations in the MAPK signaling pathway on outcome in metastatic colorectal cancer patients treated with first-line FOLFIRI and bevacizumab: data from FIRE-3 and TRIBE trials by Berger, M.D., Stintzing, S., Heinemann, V., Yang, D., Cao, S., Sunakawa, Y., Ning, Y., Matsusaka, S., Okazaki, S., Miyamoto, Y., Suenaga, M., Schirripa, M., Soni, S., Zhang, W., Falcone, A., Loupakis, F., Lenz, H.-J.

“…The MAPK-interacting kinase 1 (MKNK1) is localized downstream of the RAS/RAF/ERK and the MAP3K1/MKK/p38 signaling pathway. Through phosphorylation MKNK1…”
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Variations in genes regulating tumor-associated macrophages (TAMs) to predict outcomes of bevacizumab-based treatment in patients with metastatic colorectal cancer: results from TRIBE and FIRE3 trials by Sunakawa, Y., Stintzing, S., Cao, S., Heinemann, V., Cremolini, C., Falcone, A., Yang, D., Zhang, W., Ning, Y., Stremitzer, S., Matsusaka, S., Yamauchi, S., Parekh, A., Okazaki, S., Berger, M.D., Graver, S., Mendez, A., Scherer, S.J., Loupakis, F., Lenz, H.-J.

“…Tumor-associated macrophages (TAMs) with the M2-like phenotype are regulated by mainly NF-kB pathway including TBK1, which can influence tumor progression by…”
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Sequentially addressable dielectrophoretic array for high-throughput sorting of large-volume biological compartments by Isozaki, A, Nakagawa, Y, Loo, M H, Shibata, Y, Tanaka, N, Setyaningrum, D L, Park, J-W, Shirasaki, Y, Mikami, H, Huang, D, Tsoi, H, Riche, C T, Ota, T, Miwa, H, Kanda, Y, Ito, T, Yamada, K, Iwata, O, Suzuki, K, Ohnuki, S, Ohya, Y, Kato, Y, Hasunuma, T, Matsusaka, S, Yamagishi, M, Yazawa, M, Uemura, S, Nagasawa, K, Watarai, H, Di Carlo, D, Goda, K

“…Droplet microfluidics has become a powerful tool in precision medicine, green biotechnology, and cell therapy for single-cell analysis and selection by virtue…”
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Simultaneous measurement of mass flow rate and charge-to-mass ratio of particles in gas–solids pipe flow by Matsusaka, S., Masuda, H.

“…This paper summarizes our research on the theory and application of particle charging in gas–solids pipe flow. The particles moving in a pipe are charged by…”
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Association of variants in genes encoding for macrophage-related functions with clinical outcome in patients with locoregional gastric cancer by Sunakawa, Y., Stremitzer, S., Cao, S., Zhang, W., Yang, D., Wakatsuki, T., Ning, Y., Yamauchi, S., Stintzing, S., Sebio, A., El-khoueiry, R., Matsusaka, S., Parekh, A., Barzi, A., Azuma, M., Watanabe, M., Koizumi, W., Lenz, H.-J.

“…We provide the first evidence demonstrating that single-nucleotide polymorphisms in macrophage function-related genes may predict prognosis in locoregional…”
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Triboelectrification of pharmaceutical powders by particle impact by Watanabe, Hideo, Ghadiri, Mojtaba, Matsuyama, Tatsushi, Ding, Yu Long, Pitt, Kendal G., Maruyama, Hiroyuki, Matsusaka, Shuji, Masuda, Hiroaki

“…Pharmaceutical powders are very prone to electrostatic charging by colliding and sliding contacts with walls and other particles. In pharmaceutical formulation…”
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Germline polymorphisms in genes involved in the Hippo pathway as recurrence biomarkers in stages II/III colon cancer by Sebio, A, Matsusaka, S, Zhang, W, Yang, D, Ning, Y, Stremitzer, S, Stintzing, S, Sunakawa, Y, Yamauchi, S, Fujimoto, Y, Ueno, M, Lenz, H-J

“…The Hippo pathway regulates tissue growth and cell fate. In colon cancer, Hippo pathway deregulation promotes cellular quiescence and resistance to…”
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CXCR4 polymorphism predicts progression-free survival in metastatic colorectal cancer patients treated with first-line bevacizumab-based chemotherapy by Matsusaka, S, Cao, S, Hanna, D L, Sunakawa, Y, Ueno, M, Mizunuma, N, Zhang, W, Yang, D, Ning, Y, Stintzing, S, Sebio, A, Stremitzer, S, Yamauchi, S, Parekh, A, Okazaki, S, Berger, M D, El-Khoueiry, R, Mendez, A, Ichikawa, W, Loupakis, F, Lenz, H-J

“…We analyzed associations between CXCR4 / CXCL12 single-nucleotide polymorphisms and outcomes in metastatic colorectal cancer (mCRC) patients who underwent…”
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509 Detecting gene amplification in circulating tumor cells of patients with gastric cancer for clinical trial by Mishima, Y, Matsusaka, S, Terui, Y, Mikuniya, M, Takayama, T, Mizunuma, N, Hatake, K

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Analysis of pulsating electric signals generated in gas–solids pipe flow by Matsusaka, S., Fukuda, H., Sakura, Y., Masuda, H., Ghadiri, M.

“…In gas–solids pipe flow, particles are electrostatically charged as a result of repeated impacts on the inner walls. When a section of the pipe made of metal…”
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Variations in genes involved in dormancy associated with outcome in patients with resected colorectal liver metastases by Stremitzer, S., Zhang, W., Yang, D., Ning, Y., Stintzing, S., Sunakawa, Y., Sebio, A., Yamauchi, S., Matsusaka, S., Parekh, A., Barzi, A., El-Khoueiry, R., Stift, J., Wrba, F., Gruenberger, T., Lenz, H.-J.

“…Tumor dormancy has been described as a state of hibernation. Dormancy can be switched to proliferation by different pathways, which may play a critical role in…”
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Genetic variations in immunomodulatory pathways to predict survival in patients with locoregional gastric cancer by Sunakawa, Y, Cao, S, Volz, N B, Berger, M D, Yang, D, Parekh, A, Zhang, W, Matsusaka, S, Ning, Y, Stremitzer, S, Stintzing, S, Sebio, A, Okazaki, S, Wakatsuki, T, Azuma, M, Watanabe, M, Koizumi, W, Wu, A H, Lenz, H-J

“…Immunomodulator-targeting therapies are under development in gastric cancer (GC). However, the role of genes modulating anti-tumor immunity in GC remains…”
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P-052Phase II study of biweekly cetuximab and irinotecan as third-line therapy in patients with pre-treated KRAS exon2 wild-type metastatic colorectal cancer by Osumi, H, Shinozaki, E, Suenaga, M, Matsusaka, S, Nakayama, I, Wakatsuki, T, Ogura, M, Ozaka, M, Takashi, I, Takahari, D, Chin, K, Mizunuma, N, Yamaguchi, K

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Variations in genes involved in immune response checkpoints and association with outcomes in patients with resected colorectal liver metastases by Stremitzer, S, Sunakawa, Y, Zhang, W, Yang, D, Ning, Y, Stintzing, S, Sebio, A, Yamauchi, S, Matsusaka, S, El-Khoueiry, R, Stift, J, Wrba, F, Gruenberger, T, Lenz, H-J

“…In patients with colorectal liver metastases (CLM), liver resection offers the possibility of cure and long-term survival. The liver is a highly immunogenic…”
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A genetic variant in Rassf1a predicts outcome in mCRC patients treated with cetuximab plus chemotherapy: results from FIRE-3 and JACCRO 05 and 06 trials by Sebio, A, Stintzing, S, Heinemann, V, Sunakawa, Y, Zhang, W, Ichikawa, W, Tsuji, A, Takahashi, T, Parek, A, Yang, D, Cao, S, Ning, Y, Stremitzer, S, Matsusaka, S, Okazaki, S, Barzi, A, Berger, M D, Lenz, H-J

“…The Hippo pathway is involved in colorectal cancer (CRC) development and progression. The Hippo regulator Rassf1a is also involved in the Ras signaling…”
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Prognostic impact of FOXF1 polymorphisms in gastric cancer patients by Matsusaka, S, Wu, A H, Cao, S, Hanna, D L, Chin, K, Yang, D, Zhang, W, Ning, Y, Stintzing, S, Sebio, A, Sunakawa, Y, Stremitzer, S, Yamauchi, S, Okazaki, S, Berger, M D, Parekh, A, Miyamoto, Y, Mizunuma, N, Lenz, H-J

“…A recent genome-wide association study identified seven single-nucleotide polymorphisms (SNPs) in region 16q24, near the Forkhead box-F1 ( FOXF1 ) gene, which…”
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Estrogen receptor-beta genetic variations and overall survival in patients with locally advanced gastric cancer by Sunakawa, Y, Cao, S, Berger, M D, Matsusaka, S, Yang, D, Zhang, W, Ning, Y, Parekh, A, Stremitzer, S, Mendez, A, Okazaki, S, Wakatsuki, T, Azuma, M, Shimada, K, Watanabe, M, Koizumi, W, Wu, A H, Lenz, H-J

“…Estrogen has been shown not only to reduce the incidence of colorectal cancer but also gastric cancer (GC). Polymorphisms in estrogen receptor β gene, ESR2 ,…”
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Genetic variants associated with colorectal brain metastases susceptibility and survival by Stremitzer, S, Berghoff, A S, Volz, N B, Zhang, W, Yang, D, Stintzing, S, Ning, Y, Sunakawa, Y, Yamauchi, S, Sebio, A, Matsusaka, S, Okazaki, S, Hanna, D, Parekh, A, Mendez, A, Berger, M D, El-Khoueiry, R, Birner, P, Preusser, M, Lenz, H-J

“…Colorectal brain metastases (BM) are rare (1–2%) and a late-stage disease manifestation. Molecular mechanisms for BM development are not well understood. We…”
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2010 A genetic variant in RASSF1A, a key regulator of HIPPO pathway, predicts survival in two independent cohorts of mCRC patients treated with cetuximab-based chemotherapy by Sebio, A, Stintzing, S, Heinemann, V, Zhang, W, Sunakawa, Y, Ichikawa, W, Tsuji, A, Takahashi, T, Parekh, A, Yang, D, Cao, S, Ning, Y, Stremitzer, S, Matsusaka, S, Okazak, S, Barzi, A, Lenz, H.J

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