Search Results - "Matsuoka, Osamu"

A Compact Derivation of Quantum Potential in de Broglie–Bohm Theory by Matsuoka, Osamu

Get full text

SCO-267, a GPR40 Full Agonist, Stimulates Islet and Gut Hormone Secretion and Improves Glycemic Control in Humans by Nishizaki, Harunobu, Matsuoka, Osamu, Kagawa, Tomoya, Kobayashi, Akihiro, Watanabe, Masanori, Moritoh, Yusuke

“…SCO-267 is a full agonist of the free fatty acid receptor 1 (GPR40), which regulates the secretion of islet and gut hormones. In this phase 1 study, we aimed…”
Get full text

Nonorthogonal molecular orbital method: single-determinant theory by Watanabe, Yoshihiro, Matsuoka, Osamu

“…Using the variational principle, we have derived a variant of the Adams-Gilbert equation for nonorthogonal orbitals of a single-determinant wave function,…”
Get more information

Immunogenicity and Safety of a Two-Dose Series of a Meningococcal (Groups A, C, W, and Y) Polysaccharide Diphtheria Toxoid Conjugate Vaccine (Men-ACWY-D) in Healthy Japanese Adults by Matsuoka, Osamu, Tsuzuki, Daisuke, Suzuki, Katsuhisa, Tanaka, Tomoyuki, Takagi, Yoshiharu, Oster, Philipp

“…The quadrivalent meningococcal polysaccharide diphtheria toxoid conjugate vaccine (Men-ACWY-D) has been licensed for use in Japan since 2014. An earlier…”
Get full text

Efficacy and Safety of Alirocumab in Japanese Subjects (Phase 1 and Phase 2 Studies) by Teramoto, Tamio, MD, PhD, Kobayashi, Masahiko, RPh, MS, Uno, Kiyoko, MD, PhD, Takagi, Yoshiharu, MS, Matsuoka, Osamu, MD, Sugimoto, Masayuki, MD, Inoue, Satoshi, MD, Minami, Fumiko, MD, Baccara-Dinet, Marie Thérèse, MD, MSc

“…Abstract We assessed the safety and tolerability of ascending single doses of alirocumab in healthy Japanese subjects, and evaluated the effect of alirocumab…”
Get full text

Efficacy and Safety of Bococizumab (RN316/PF-04950615), a Monoclonal Antibody Against Proprotein Convertase Subtilisin/Kexin Type 9, in Hypercholesterolemic Japanese Subjects Receiving a Stable Dose of Atorvastatin or Treatment-Naive　― Results From a Randomized, Placebo-Controlled, Dose-Ranging Study by Yokote, Koutaro, Kanada, Shigeto, Matsuoka, Osamu, Sekino, Hisakuni, Imai, Keiji, Tabira, Junichi, Matsuoka, Nobushige, Chaudhuri, Sandip, Teramoto, Tamio

“…Background:A Phase 2, dose-ranging study of bococizumab, a monoclonal anti-proprotein convertase subtilisin/kexin type 9 antibody, was conducted in Japanese…”
Get full text

Immunogenicity and Safety of a Quadrivalent Meningococcal Tetanus Toxoid-Conjugate Vaccine (MenACYW-TT) in Meningococcal Vaccine-Naïve Participants across a Broad Age Range (2–55 Years) in Japan: a Phase III Randomized Study by Matsuoka, Osamu, Ujiie, Mugen, Kikuchi, Hitoshi, Otake, Sachiko, Chansinghakul, Danaya, Inoue, Takahiro, Varghese, Kucku, Sirisuphmitr, Nuchra, Hashiguchi, Tomoyuki, Zambrano, Betzana, Nakama, Takahiro, Frago, Carina, Jordanov, Emilia, Dhingra, Mandeep Singh

“…MenACYW-TT is a quadrivalent meningococcal tetanus toxoid-conjugate vaccine designed to prevent invasive meningococcal disease. The primary objective of this…”
Get full text

Long Term Follow-Up Study of a Randomized, Open-Label, Uncontrolled, Phase I/II Study to Assess the Safety and Immunogenicity of Intramuscular and Intradermal Doses of COVID-19 DNA Vaccine (AG0302-COVID19) by Nakagami, Hironori, Matsumoto, Tetsuya, Takazawa, Kenji, Sekino, Hisakuni, Matsuoka, Osamu, Inoue, Satoshi, Furuie, Hidetoshi, Morishita, Ryuichi

“…Pharmacological studies have demonstrated antibody production and infection prevention with an intradermal coronavirus disease 2019 (COVID-19) DNA vaccine…”
Get full text

A Highly Efficient Cu/Al(OH)3 Catalyst for the Hydration of Acrylonitrile to Acrylamide by Ichikawa, Shinichiro, Miyazoe, Satoru, Matsuoka, Osamu

“…A highly efficient, easily filterable Cu/Al(OH)3 catalyst for the hydration of acrylonitrile to acrylamide has been synthesized by reducing a…”
Get full text

Safety and immunogenicity of Clostridium difficile toxoid vaccine in Japanese adults by Matsuoka, Osamu, Patel, Dhaval M., Sasaki, Shin, Oka, Hayato, Sasaki, Toru, Pietrobon, Patricia J., Laot, Thelma, Bouckenooghe, Alain, Menezes, Josemund, de Bruyn, Guy

“…This was a randomized, placebo-controlled, Phase I/II study conducted in a Japanese cohort to assess the safety and immunogenicity of Clostridium difficile…”
Get full text

Chain Structures of Surface Hydroxyl Groups Formed via Line Oxygen Vacancies on TiO2(110) Surfaces Studied Using Noncontact Atomic Force Microscopy by Namai, Yoshimichi, Matsuoka, Osamu

“…Structures of surface hydroxyl groups arranged on a reduced TiO2(110) surface that had line oxygen vacancies were studied using noncontact atomic force…”
Get full text

Assessment of Vasoactive Agents and Vascular Aging by the Second Derivative of Photoplethysmogram Waveform by Takazawa, Kenji, Tanaka, Nobuhiro, Fujita, Masami, Matsuoka, Osamu, Saiki, Tokuyu, Aikawa, Masaru, Tamura, Sinobu, Ibukiyama, Chiharu

“…To evaluate the clinical application of the second derivative of the fingertip photoplethysmogram waveform, we performed drug administration studies (study 1)…”
Get full text

Expression of estrogen receptor α and β in reactive astrocytes at the male rat hippocampus after status epilepticus by Sakuma, Satoru, Tokuhara, Daisuke, Hattori, Hideji, Matsuoka, Osamu, Yamano, Tsunekazu

“…Estrogen is neuroprotective against status epilepticus (SE)‐induced hippocampal damage in female animals. In male animals, estrogen is converted from…”
Get full text

Relativistic Gaussian basis sets for molecular calculations: Fully optimized single-family exponent basis sets for HHg by Watanabe, Yoshihiro, Tatewaki, Hiroshi, Koga, Toshikatsu, Matsuoka, Osamu

“…Relativistic single‐family exponent Gaussian basis sets for molecular calculations are presented for the 80 atoms 1H through 80Hg. The exponent parameters…”
Get full text

Kainic acid dose affects delayed cell death mechanism after status epilepticus by Tokuhara, Daisuke, Sakuma, Satoru, Hattori, Hideji, Matsuoka, Osamu, Yamano, Tsunekazu

“…Kainic acid (KA)-induced status epilepticus (SE) produces hippocampal neuronal death, which varies from necrosis to apoptosis or programmed cell death (PCD)…”
Get full text

NC-AFM Observation of Atomic Scale Structure of Rutile-type TiO2(110) Surface Prepared by Wet Chemical Process by Namai, Yoshimichi, Matsuoka, Osamu

“…We succeeded in observing the atomic scale structure of a rutile-type TiO2(110) single-crystal surface prepared by the wet chemical method of chemical etching…”
Get full text

Observation of a LiCoO2 Cathode Material of a Li-Ion Battery by High Spatial Resolution TOF-SIMS by Ohnishi, Miwa, Matsuoka, Osamu, Nogi, Hidenobu, Sakamoto, Tetsuo

“…Lithium (Li)-ion batteries will be important to future generations for use as clean energy-storage devices. However, the surface chemical reaction mechanism of…”
Get full text

Surface Characterization of Polyamic Acid and Polyimide Films Prepared by Vapor Deposition Polymerization by Using Sum-Frequency Generation by Miyamae, Takayuki, Tsukagoshi, Kiyomi, Matsuoka, Osamu, Yamamoto, Sadaaki, Nozoye, Hisakazu

“…The surface structures of polyamic acid and polyimide films made by vapor deposition polymerization (VDP) technique were investigated using infrared−visible…”
Get full text

Anisotropic Growth of J Aggregates of Pseudoisocyanine Dye at a Mica/Solution Interface Revealed by AFM and Polarization Absorption Measurements by Ono, Shoko Sugiyama, Yao, Hiroshi, Matsuoka, Osamu, Kawabata, Ren, Kitamura, Noboru, Yamamoto, Sadaaki

“…We investigated the J-aggregation process of pseudoisocyanine chloride at a mica/solution interface by using tapping mode atomic force microscopy (TM-AFM) and…”
Get full text

Safety/tolerability, efficacy and pharmacokinetics of 600-μg cotadutide in Japanese type 2 diabetes patients with a body mass index of 25 kg/m 2 or higher: A phase I, randomized, double-blind, placebo-controlled study by Asano, Michiko, Sekikawa, Akiko, Sugeno, Masatoshi, Matsuoka, Osamu, Robertson, Darren, Hansen, Lars

“…To assess the safety/tolerability, efficacy and pharmacokinetics of once-daily, 600-μg cotadutide in Japanese type 2 diabetes patients with a body mass index…”
Get full text