Search Results - "Matsuo, Yushi"

Pharmacological Properties of JTE-952, an Orally Available and Selective Colony Stimulating Factor 1 Receptor Kinase Inhibitor by Uesato, Naofumi, Miyagawa, Naoki, Inagaki, Koji, Kakefuda, Reina, Kitagawa, Yoshihiro, Matsuo, Yushi, Yamaguchi, Takayuki, Hata, Takahiro, Ikegashira, Kazutaka, Matsushita, Mutsuyoshi

“…Colony stimulating factor 1 (CSF1) receptor (CSF1R) is a receptor protein-tyrosine kinase specifically expressed in monocyte-lineage cells, such as monocytes…”
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JTE-952 Suppresses Bone Destruction in Collagen-Induced Arthritis in Mice by Inhibiting Colony Stimulating Factor 1 Receptor by Uesato, Naofumi, Inagaki, Koji, Miyagawa, Naoki, Kitagawa, Yoshihiro, Kakefuda, Reina, Matsuo, Yushi, Yamaguchi, Takayuki, Hata, Takahiro, Ikegashira, Kazutaka, Matsushita, Mutsuyoshi

“…Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation and structural destruction of the joints. Bone damage occurs…”
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Therapeutic Effect of Colony Stimulating Factor 1 Receptor Kinase Inhibitor, JTE-952, on Methotrexate-Refractory Pathology in a Rat Model of Rheumatoid Arthritis by Uesato, Naofumi, Kitagawa, Yoshihiro, Matsuo, Yushi, Miyagawa, Naoki, Inagaki, Koji, Kakefuda, Reina, Yamaguchi, Takayuki, Hata, Takahiro, Ikegashira, Kazutaka, Matsushita, Mutsuyoshi

“…Rheumatoid arthritis (RA) is an autoimmune disease characterized by inflammation and the destruction of bone and cartilage in affected joints. One of the unmet…”
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JTT-305, an orally active calcium-sensing receptor antagonist, stimulates transient parathyroid hormone release and bone formation in ovariectomized rats by Kimura, Shuichi, Nakagawa, Takashi, Matsuo, Yushi, Ishida, Yuji, Okamoto, Yoshihisa, Hayashi, Mikio

“…Intermittent administration of parathyroid hormone (PTH) has a potent anabolic effect on bone in humans and animals. Calcium-sensing receptor (CaSR)…”
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Denitrification, a Novel Type of Respiratory Metabolism in Fungal Mitochondrion by Kobayashi, Michiyoshi, Matsuo, Yushi, Takimoto, Akiko, Suzuki, Sawako, Maruo, Fumiaki, Shoun, Hirofumi

“…Subcellular localization and coupling to ATP synthesis were investigated with respect to the denitrifying systems of two fungi, Fusarium oxysporum and…”
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Interaction of naphthalene derivatives with lipids in membranes studied by the 1H-nuclear Overhauser effect and molecular dynamics simulation by Shintani, Megumi, Matsuo, Yushi, Sakuraba, Shun, Matubayasi, Nobuyuki

“…The location, orientation, and dynamics of hydrophobic small molecules in lipid membranes are studied through combined use of solution-state (1)H-NMR and MD…”
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New aminopropandiol derivatives as orally available and short-acting calcium-sensing receptor antagonists by Shinagawa, Yuko, Inoue, Teruhiko, Hirata, Kazuyuki, Katsushima, Takeo, Nakagawa, Takashi, Matsuo, Yushi, Shindo, Masanori, Hashimoto, Hiromasa

“…The discovery of an orally available and short-acting calcium-sensing receptor antagonist (R,R)-31 is reported. Synthesis and structure–activity relationship…”
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Discovery of a Potent and Short−Acting Oral Calcilytic with a Pulsatile Secretion of Parathyroid Hormone by Shinagawa, Yuko, Inoue, Teruhiko, Katsushima, Takeo, Kiguchi, Toshihiro, Ikenogami, Taku, Ogawa, Naoki, Fukuda, Kenji, Hirata, Kazuyuki, Harada, Kazuhito, Takagi, Masaki, Nakagawa, Takashi, Kimura, Shuichi, Matsuo, Yushi, Maekawa, Mariko, Hayashi, Mikio, Soejima, Yuki, Takahashi, Mitsuru, Shindo, Masanori, Hashimoto, Hiromasa

“…Short-acting oral calcilytics, calcium-sensing receptor (CaSR) antagonists, have been considered as alternatives for parathyroid hormone (PTH), an injectable…”
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Molecular cloning and sequencing of the extracellular pectate lyase II gene from Erwinia carotovora Er by Yoshida, Aruto, Matsuo, Yushi, Kamio, Yoshiyuki, Izaki, Kazuo

“…Erwinia carotovora Er produces three extra-cellular pectate lyases (PL I, II, and III). The gene for peetate lyase II (pelII) of E. carotovora Er was cloned…”
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Denitrification by the fungus Cylindrocarpon tonkinense: anaerobic cell growth and two isozyme forms of cytochrome P-450nor by Usuda, K. (University of Tsukuba, Tsukuba, Ibaraki, Japan), Toritsuka, N, Matsuo, Y, Kim, D, Shoun, H

“…We examined the denitrification system of the fungus Cylindrocarpon tonkinense and found several properties distinct from those of the denitrification system…”
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Studies on snake venoms. XIX. Purification and some physicochemical properties of proteinases a and c from the venom of Agkistrodon halys blomhoffii by Oshima, G, Matsuo, Y, Iwanaga, S, Suzuki, T

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