Search Results - "Matsunobu, Tomoya"

Synthesis of substituted (trifluoromethyl)alkenes: (Trifluoromethyl)alkylidenation of thioketones via CF3-thiiranes by Fuchibe, Kohei, Matsunobu, Tomoya, Ichikawa, Junji

“…•The synthesis of (trifluoromethyl)alkenes, including fully substituted variants, was studied.•Thioketones underwent the Barton–Kellogg reaction with…”
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Tumor microenvironment in giant cell tumor of bone: evaluation of PD-L1 expression and SIRPα infiltration after denosumab treatment by Toda, Yu, Kohashi, Kenichi, Yamamoto, Hidetaka, Ishihara, Shin, Ito, Yoshihiro, Susuki, Yosuke, Kawaguchi, Kengo, Kiyozawa, Daisuke, Takamatsu, Dai, Kinoshita, Izumi, Yamada, Yuichi, Maehara, Junki, Kimura, Atsushi, Tamiya, Sadafumi, Taguchi, Kenichi, Matsunobu, Tomoya, Matsumoto, Yoshihiro, Nakashima, Yasuharu, Mawatari, Masaaki, Oda, Yoshinao

“…Giant cell tumor of bone (GCTB) is an intermediate malignant bone tumor that is locally aggressive and rarely metastasizes. Denosumab, which is a receptor…”
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Analysis of a limb-specific regulatory element in the promoter of the link protein gene by Rhodes, Craig S., Matsunobu, Tomoya, Yamada, Yoshihiko

“…Link protein is encoded by the Hapln1 gene and is a prototypical protein found in the cartilage matrix. It acts as an important component of the endochondral…”
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Risk factors of local recurrence after surgery in extraabdominal desmoid‐type fibromatosis: A multicenter study in Japan by Nishida, Yoshihiro, Hamada, Shunsuke, Kawai, Akira, Kunisada, Toshiyuki, Ogose, Akira, Matsumoto, Yoshihiro, Ae, Keisuke, Toguchida, Junya, Ozaki, Toshifumi, Hirakawa, Akihiro, Motoi, Toru, Sakai, Tomohisa, Kobayashi, Eisuke, Gokita, Tabu, Okamoto, Takeshi, Matsunobu, Tomoya, Shimizu, Koki, Koike, Hiroshi

“…This study was undertaken to clarify the risk factors, including the mutation status of CTNNB1, for the local recurrence after surgery of the rare disease…”
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Impact of COVID-19 pandemic on bone and soft tissue sarcoma patients’ consultation and diagnosis by Oyama, Ryunosuke, Endo, Makoto, Shimada, Eijiro, Matsunobu, Tomoya, Setsu, Nokitaka, Ishihara, Shin, Kanahori, Masaya, Kawaguchi, Kengo, Hirose, Takeshi, Nabeshima, Akira, Fujiwara, Toshifumi, Yoshimoto, Masato, Maekawa, Akira, Hanada, Masuo, Yokoyama, Nobuhiko, Matsumoto, Yoshihiro, Nakashima, Yasuharu

“…The coronavirus disease (COVID-19) pandemic negatively affected the diagnosis and treatment of several cancer types. However, this pandemic’s exact impact and…”
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Nuclear β-catenin translocation plays a key role in osteoblast differentiation of giant cell tumor of bone by Kimura, Atsushi, Toda, Yu, Matsumoto, Yoshihiro, Yamamoto, Hidetaka, Yahiro, Kenichiro, Shimada, Eijiro, Kanahori, Masaya, Oyama, Ryunosuke, Fukushima, Suguru, Nakagawa, Makoto, Setsu, Nokitaka, Endo, Makoto, Fujiwara, Toshifumi, Matsunobu, Tomoya, Oda, Yoshinao, Nakashima, Yasuharu

“…Denosumab is a game-changing drug for giant cell tumor of bone (GCTB); however, its clinical biomarker regarding tumor ossification of GCTB has not been…”
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A pseudoaneurysm of the popliteal artery probably pierced by a bone spike arising in the spontaneously regressed osteochondroma: A case report by Yasuda, Naohiro, Nakai, Sho, Nakai, Takaaki, Outani, Hidetatsu, Takenaka, Satoshi, Hamada, Ken-ichiro, Matsunobu, Tomoya, Yoshikawa, Hideki, Naka, Norifumi

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Definitive radiation therapy in patients with unresectable desmoid tumors: a systematic review by Matsunobu, Tomoya, Kunisada, Toshiyuki, Ozaki, Toshifumi, Iwamoto, Yukihide, Yoshida, Masahiro, Nishida, Yoshihiro

“…Desmoid tumors are rare soft tissue tumors. Wide local excision has been the standard surgical treatment for desmoid tumors. However, this procedure results in…”
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Clinical features and treatment outcome of desmoid-type fibromatosis: based on a bone and soft tissue tumor registry in Japan by Nishida, Yoshihiro, Kawai, Akira, Toguchida, Junya, Ogose, Akira, Ae, Keisuke, Kunisada, Toshiyuki, Matsumoto, Yoshihiro, Matsunobu, Tomoya, Takahashi, Kunihiko, Nishida, Kazuki, Ozaki, Toshifumi

“…Background Treatment modality of desmoid-type fibromatosis (DF) has changed from surgery with a wide surgical margin to conservative treatment. In this study,…”
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Myxoid liposarcoma in an 11-year-old patient by Matsunobu, Tomoya, Maekawa, Akira, Inaba, Yuna, Makihara, Kosuke, Hisaoka, Masanori, Iwamoto, Yukihide

“…Myxoid liposarcoma is a mesenchymal malignancy that most commonly presents in young adults, with peak incidence between the ages of 30–50 years. The clinical…”
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Expression of Forkhead box M1 in soft tissue leiomyosarcoma: Clinicopathologic and in vitro study using a newly established cell line by Maekawa, Akira, Kohashi, Kenichi, Setsu, Nokitaka, Kuda, Masaaki, Iura, Kunio, Ishii, Takeaki, Matsunobu, Tomoya, Nakatsura, Tetsuya, Iwamoto, Yukihide, Oda, Yoshinao

“…Leiomyosarcoma (LMS) of soft tissue is a sarcoma with smooth‐muscle differentiation, and conventional chemotherapy does not improve its outcome. The…”
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Hypoxia-inducible factor 1 alpha is a poor prognostic factor and potential therapeutic target in malignant peripheral nerve sheath tumor by Fukushima, Suguru, Endo, Makoto, Matsumoto, Yoshihiro, Fukushi, Jun-Ichi, Matsunobu, Tomoya, Kawaguchi, Ken-Ichi, Setsu, Nokitaka, IIda, Keiichiro, Yokoyama, Nobuhiko, Nakagawa, Makoto, Yahiro, Kenichiro, Oda, Yoshinao, Iwamoto, Yukihide, Nakashima, Yasuharu

“…Malignant peripheral nerve sheath tumor (MPNST) is a rare soft tissue sarcoma with poor prognosis. Hypoxia-inducible factor 1 (HIF-1) plays a crucial role in…”
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Perlecan modulates VEGF signaling and is essential for vascularization in endochondral bone formation by Ishijima, Muneaki, Suzuki, Nobuharu, Hozumi, Kentaro, Matsunobu, Tomoya, Kosaki, Keisuke, Kaneko, Haruka, Hassell, John R., Arikawa-Hirasawa, Eri, Yamada, Yoshihiko

“…Perlecan (Hspg2) is a heparan sulfate proteoglycan expressed in basement membranes and cartilage. Perlecan deficiency (Hspg2−/−) in mice and humans causes…”
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Ossifying fibromyxoid tumor presenting EP400-PHF1 fusion gene by Endo, Makoto, MD, PhD, Kohashi, Kenichi, MD, PhD, Yamamoto, Hidetaka, MD, PhD, Ishii, Takeaki, MD, Yoshida, Tatsuya, MD, Matsunobu, Tomoya, MD, PhD, Iwamoto, Yukihide, MD, PhD, Oda, Yoshinao, MD, PhD

“…Summary Ossifying fibromyxoid tumor is a rare soft tissue tumor of borderline malignancy and uncertain differentiation. Recently, a novel fusion gene,…”
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Correction: Hypoxia-inducible factor 1 alpha is a poor prognostic factor and potential therapeutic target in malignant peripheral nerve sheath tumor by Fukushima, Suguru, Endo, Makoto, Matsumoto, Yoshihiro, Fukushi, Jun-Ichi, Matsunobu, Tomoya, Kawaguchi, Ken-Ichi, Setsu, Nokitaka, IIda, Keiichiro, Yokoyama, Nobuhiko, Nakagawa, Makoto, Yahiro, Kenichiro, Oda, Yoshinao, Iwamoto, Yukihide, Nakashima, Yasuharu

“…[This corrects the article DOI: 10.1371/journal.pone.0178064.]…”
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Tumor-induced osteomalacia caused by a massive phosphaturic mesenchymal tumor of the acetabulum: A case report by Nakamura, Kimitaka, Ohishi, Masanobu, Matsunobu, Tomoya, Nakashima, Yasuharu, Sakamoto, Akio, Maekawa, Akira, Oda, Yoshinao, Iwamoto, Yukihide

“…We report a case of tumor-induced osteomalacia (TIO) caused by a massive phosphaturic mesenchymal tumor (PMT) of the acetabulum. A 68-year-old woman presented…”
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Activation of ERK1/2 Causes Pazopanib Resistance via Downregulation of DUSP6 in Synovial Sarcoma Cells by Yokoyama, Nobuhiko, Matsunobu, Tomoya, Matsumoto, Yoshihiro, Fukushi, Jun-ichi, Endo, Makoto, Hatano, Mihoko, Nabeshima, Akira, Fukushima, Suguru, Okada, Seiji, Iwamoto, Yukihide

“…Synovial sarcoma (SS) is a rare high-grade malignant mesenchymal tumour with a relatively poor prognosis despite intensive multimodal therapy. Although…”
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Desmoplastic Fibroblastoma Invading the Humerus by Iwamoto, Yukihide, Makihara, Kosuke, Jotatsu, Mao, Fukushima, Suguru, Maekawa, Akira, Matsunobu, Tomoya, Hisaoka, Masanori

“…Desmoplastic fibroblastoma (DFB) is an uncommon, benign, soft tissue tumor. The tumor most often presents as a slowly growing, painless soft tissue mass and is…”
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Does the Use of Peripheral Immune-Related Markers Indicate Whether to Administer Pazopanib, Trabectedin, or Eribulin to Advanced Soft Tissue Sarcoma Patients? by Shimada, Eijiro, Endo, Makoto, Matsumoto, Yoshihiro, Tsuchihashi, Kenji, Ito, Mamoru, Kusaba, Hitoshi, Nabeshima, Akira, Nawata, Tomoya, Maekawa, Akira, Matsunobu, Tomoya, Setsu, Nokitaka, Fujiwara, Toshifumi, Iida, Keiichiro, Nakagawa, Makoto, Hirose, Takeshi, Kanahori, Masaya, Oyama, Ryunosuke, Isobe, Taichi, Ariyama, Hiroshi, Kohashi, Kenichi, Yamamoto, Hidetaka, Oda, Yoshinao, Iwamoto, Yukihide, Akashi, Koichi, Baba, Eishi, Nakashima, Yasuharu

“…Pazopanib, trabectedin, and eribulin are administered for the treatment of soft tissue sarcomas (STSs); however, there is little consensus on which agent…”
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Factors associated with the decision of operative procedure for proximal femoral bone metastasis: Questionnaire survey to institutions participating the Bone and Soft Tissue Tumor Study Group of the Japan Clinical Oncology Group by Araki, Nobuhito, Chuman, Hirokazu, Matsunobu, Tomoya, Tanaka, Kazuhiro, Katagiri, Hirohisa, Kunisada, Toshiyuki, Hiruma, Toru, Hiraga, Hiroaki, Morioka, Hideo, Hatano, Hiroshi, Asanuma, Kunihiro, Nishida, Yoshihiro, Hiraoka, Koji, Okamoto, Takeshi, Abe, Satoshi, Watanuki, Munenori, Morii, Takeshi, Sugiura, Hideshi, Yoshida, Yukihiro, Ohno, Takatoshi, Outani, Hidetatsu, Yokoyama, Koichiro, Shimose, Shoji, Fukuda, Haruhiko, Iwamoto, Yukihide

“…Pathological fracture of the proximal femur is a main cause of cancer patients losing their ability to walk. Although both osteosynthetic devices…”
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