Search Results - "Matsuno, Kuniharu"

The NOX1 isoform of NADPH oxidase is involved in dysfunction of liver sinusoids in nonalcoholic fatty liver disease by Matsumoto, Misaki, Zhang, Jia, Zhang, Xueqing, Liu, Junjie, Jiang, Joy X., Yamaguchi, Kanji, Taruno, Akiyuki, Katsuyama, Masato, Iwata, Kazumi, Ibi, Masakazu, Cui, Wenhao, Matsuno, Kuniharu, Marunaka, Yoshinori, Itoh, Yoshito, Torok, Natalie J., Yabe-Nishimura, Chihiro

“…The increased production of reactive oxygen species (ROS) has been postulated to play a key role in the progression of nonalcoholic fatty liver disease…”
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Physiological roles of NOX/NADPH oxidase, the superoxide-generating enzyme by Katsuyama, Masato, Matsuno, Kuniharu, Yabe-Nishimura, Chihiro

“…NADPH oxidase is a superoxide (O(2) (•-))-generating enzyme first identified in phagocytes, essential for their bactericidal activities. Later, in…”
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ROS‐generating oxidases Nox1 and Nox4 contribute to oncogenic Ras‐induced premature senescence by Kodama, Ryo, Kato, Masayoshi, Furuta, Shuichi, Ueno, Shouta, Zhang, Yugen, Matsuno, Kuniharu, Yabe‐Nishimura, Chihiro, Tanaka, Eiji, Kamata, Tohru

“…Activated oncogenes induce premature cellular senescence, a permanent state of proliferative arrest in primary rodent and human fibroblasts. Recent studies…”
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Up-regulation of NOX1/NADPH oxidase following drug-induced myocardial injury promotes cardiac dysfunction and fibrosis by Iwata, Kazumi, Matsuno, Kuniharu, Murata, Ayumi, Zhu, Kai, Fukui, Hitomi, Ikuta, Keiko, Katsuyama, Masato, Ibi, Masakazu, Matsumoto, Misaki, Ohigashi, Makoto, Wen, Xiaopeng, Zhang, Jia, Cui, Wenhao, Yabe-Nishimura, Chihiro

“…Cardiac fibrosis is a common feature in failing heart and therapeutic strategy to halt the progression of fibrosis is highly needed. We here report on NOX1, a…”
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Reactive Oxygen Species Derived from NOX1/NADPH Oxidase Enhance Inflammatory Pain by Ibi, Masakazu, Matsuno, Kuniharu, Shiba, Dai, Katsuyama, Masato, Iwata, Kazumi, Kakehi, Tomoko, Nakagawa, Takayuki, Sango, Kazunori, Shirai, Yasuhito, Yokoyama, Takahiko, Kaneko, Shuji, Saito, Naoaki, Yabe-Nishimura, Chihiro

“…The involvement of reactive oxygen species (ROS) in an augmented sensitivity to painful stimuli (hyperalgesia) during inflammation has been suggested, yet how…”
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Erythropoietin-Mobilized Endothelial Progenitors Enhance Reendothelialization via Akt–Endothelial Nitric Oxide Synthase Activation and Prevent Neointimal Hyperplasia by Urao, Norifumi, Okigaki, Mitsuhiko, Yamada, Hiroyuki, Aadachi, Yasushi, Matsuno, Kuniharu, Matsui, Akihiro, Matsunaga, Shinsaku, Tateishi, Kento, Nomura, Tetsuya, Takahashi, Tomosaburo, Tatsumi, Tetsuya, Matsubara, Hiroaki

“…We investigated whether the mobilization of endothelial progenitor cells (EPCs) by exogenous erythropoietin (Epo) promotes the repair of injured endothelium…”
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Involvement of NOX1/NADPH oxidase in morphine-induced analgesia and tolerance by Ibi, Masakazu, Matsuno, Kuniharu, Matsumoto, Misaki, Sasaki, Mika, Nakagawa, Takayuki, Katsuyama, Masato, Iwata, Kazumi, Zhang, Jia, Kaneko, Shuji, Yabe-Nishimura, Chihiro

“…The involvement of reactive oxygen species (ROS) in morphine-induced analgesia and tolerance has been suggested, yet how and where ROS take part in these…”
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Potential role of the NADPH oxidase NOX1 in the pathogenesis of 5-fluorouracil-induced intestinal mucositis in mice by Yasuda, Masashi, Kato, Shinichi, Yamanaka, Naoki, Iimori, Maho, Utsumi, Daichi, Kitahara, Yumeno, Iwata, Kazumi, Matsuno, Kuniharu, Amagase, Kikuko, Yabe-Nishimura, Chihiro, Takeuchi, Koji

“…Although NADPH oxidase 1 (NOX1) has been shown to be highly expressed in the gastrointestinal tract, the physiological and pathophysiological roles of this…”
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Deficiency of NOX1/Nicotinamide Adenine Dinucleotide Phosphate, Reduced Form Oxidase Leads to Pulmonary Vascular Remodeling by Iwata, Kazumi, Ikami, Kanako, Matsuno, Kuniharu, Yamashita, Toshiharu, Shiba, Dai, Ibi, Masakazu, Matsumoto, Misaki, Katsuyama, Masato, Cui, Wenhao, Zhang, Jia, Zhu, Kai, Takei, Norio, Kokai, Yasuo, Ohneda, Osamu, Yokoyama, Takahiko, Yabe-Nishimura, Chihiro

“…OBJECTIVE—Involvement of reactive oxygen species derived from nicotinamide adenine dinucleotide phosphate, reduced form (NADPH) oxidase has been documented in…”
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Sp3 transcription factor is crucial for transcriptional activation of the human NOX4 gene by Katsuyama, Masato, Hirai, Hideyo, Iwata, Kazumi, Ibi, Masakazu, Matsuno, Kuniharu, Matsumoto, Misaki, Yabe-Nishimura, Chihiro

“…NOX is the catalytic subunit of NADPH oxidase, the superoxide-generating enzyme. Among several isoforms of NOX, NOX4 is abundantly expressed in various…”
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NADPH Oxidase Isoforms and Anti-hypertensive Effects of Atorvastatin Demonstrated in Two Animal Models by Cui, Wenhao, Matsuno, Kuniharu, Iwata, Kazumi, Ibi, Masakazu, Katsuyama, Masato, Kakehi, Tomoko, Sasaki, Mika, Ikami, Kanako, Zhu, Kai, Yabe-Nishimura, Chihiro

“…Beneficial effects of statins on cardiovascular diseases have been attributed to decreased generation of reactive oxygen species (ROS). We tested the…”
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Increased Gene Expression of Glutathione Peroxidase-3 in Diabetic Mouse Heart by Iwata, Kazumi, Nishinaka, Toru, Matsuno, Kuniharu, Yabe-Nishimura, Chihiro

“…Increased incidence of heart disease is reported in patients with diabetes. To elucidate a molecular profile of expressed genes during the progression of…”
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The Activity of Aldose Reductase Is Elevated in Diabetic Mouse Heart by Iwata, Kazumi, Nishinaka, Toru, Matsuno, Kuniharu, Kakehi, Tomoko, Katsuyama, Masato, Ibi, Masakazu, Yabe-Nishimura, Chihiro

“…The importance of aldose reductase (AR) has been implicated in the pathogenesis of diabetic complications, although the alterations in the expression and…”
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Aldose Reductase Inhibitors Improve Myocardial Reperfusion Injury in Mice by a Dual Mechanism by Iwata, Kazumi, Matsuno, Kuniharu, Nishinaka, Toru, Persson, Christina, Yabe-Nishimura, Chihiro

“…Aldose reductase (AR) has been implicated in the pathogenesis of diabetic complications, although the clinical efficacy of AR inhibitors has not been clearly…”
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The AP-1 site is essential for the promoter activity of NOX1/NADPH oxidase, a vascular superoxide-producing enzyme: Possible involvement of the ERK1/2-JunB pathway by Cevik, Muhammer Ozgur, Katsuyama, Masato, Kanda, Sayaka, Kaneko, Tetsuo, Iwata, Kazumi, Ibi, Masakazu, Matsuno, Kuniharu, Kakehi, Tomoko, Cui, Wenhao, Sasaki, Mika, Yabe-Nishimura, Chihiro

“…NADPH oxidase is a major source of the superoxide produced in cardiovascular tissues. The expression of NOX1, a catalytic subunit of NADPH oxidase, is induced…”
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Myocyte enhancer factor 2B is involved in the inducible expression of NOX1/NADPH oxidase, a vascular superoxide-producing enzyme by Katsuyama, Masato, Ozgur Cevik, Muhammer, Arakawa, Noriaki, Kakehi, Tomoko, Nishinaka, Toru, Iwata, Kazumi, Ibi, Masakazu, Matsuno, Kuniharu, Yabe-Nishimura, Chihiro

“…NADPH oxidase is a major source of the superoxide produced in cardiovascular tissues. Expression of NOX1, a catalytic subunit of NADPH oxidase, is induced by…”
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Novel transcripts of Nox1 are regulated by alternative promoters and expressed under phenotypic modulation of vascular smooth muscle cells by Arakawa, Noriaki, Katsuyama, Masato, Matsuno, Kuniharu, Urao, Norifumi, Tabuchi, Yoshiaki, Okigaki, Mitsuhiko, Matsubara, Hiroaki, Yabe-Nishimura, Chihiro

“…NADPH oxidase is implicated in the pathogenesis of various cardiovascular disorders. In vascular smooth muscle cells (VSMC), expression of NOX1 (NADPH oxidase…”
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A novel role for Nox1/NADPH oxidase in morphine tolerance by Ibi, Masakazu, Matsuno, Kuniharu, Uchimaki, Hirosuke, Yabe-Nishimura, Chihiro

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336 - Reactive Oxygen Species Derived from the NOX1 Isoform of NADPH Oxidase Exacerbate Doxorubicin-Induced Cardiotoxicity by Promoting Cardiac Remodeling by Iwata, Kazumi, Matsuno, Kuniharu, Yabe-Nishimura, Chihiro

“…The anthracycline antitumor agent, doxorubicin (DOX) is known to cause dose-dependent cardiotoxicity. Involvement of NADPH oxidase in DOX-induced…”
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Reactive Oxygen Species Derived from the NOX1 Isoform of NADPH Oxidase Exacerbate Doxorubicin-Induced Cardiotoxicity by Promoting Cardiac Remodeling by Iwata, Kazumi, Matsuno, Kuniharu, Yabe-Nishimura, Chihiro

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