Search Results - "Matsumura, Toshiharu"

The significant improvement of survival times and pathological parameters by bioartificial liver with recombinant HepG2 in porcine liver failure model by Enosawa, Shin, Miyashita, Tomoyuki, Saito, Tomohiro, Omasa, Takeshi, Matsumura, Toshiharu

“…We developed a bioartificial liver (BAL) containing human hepatoblastoma cell line, HepG2, with the addition of ammonia removal activity by transfecting a…”
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Oriental Medicinal Herb, Periploca sepium, Extract Inhibits Growth and IL-6 Production of Human Synovial Fibroblast-Like Cells by Tokiwa, Takayoshi, Harada, Kuniaki, Matsumura, Toshiharu, Tukiyama, Takashi

“…Periploca sepium (PS) has traditionally been used in oriental medicine for treatment of rheumatoid arthritis (RA). We investigated the aqueous extract of PS…”
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Double-compartment cell culture apparatus: construction and biochemical evaluation for bioartificial liver support by Takahashi, Masahiro, Sakurai, Masayuki, Enosawa, Shin, Omasa, Takeshi, Tsuruoka, Shuichi, Matsumura, Toshiharu

“…Functional demands on a bioartificial liver support (BAL) device are not limited to biosynthetic activities, but must also encompass metabolic removal of…”
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Oriental Medicinal Herb,Periploca sepium,Extract Inhibits Growth and IL-6 Production of Human Synovial Fibroblast-Like Cells by Takayoshi TOKIWA, Kuniaki HARADA, Toshiharu MATSUMURA, Takashi TUKIYAMA

“…Periploca sepium (PS) has traditionally been used in oriental medicine for treatment of rheumatoid arthritis (RA). We investigated the aqueous extract of PS…”
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In vivo estimation of bioartificial liver with recombinant HepG2 cells using pigs with ischemic liver failure by Enosawa, S, Miyashita, T, Fujita, Y, Suzuki, S, Amemiya, H, Omasa, T, Hiramatsu, S, Suga, K, Matsumura, T

“…Biological efficacy of a recombinant human hepatic cell line, glutamine synthetase transfected HepG2 (GS-HepG2), was examined with large-scale culture in a…”
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Long-term culture of glutamine synthetase-transfected HepG2 cells in circulatory flow bioreactor for development of a bioartificial liver by Enosawa, S, Miyashita, T, Suzuki, S, Li, X K, Tsunoda, M, Amemiya, H, Yamanaka, M, Hiramatsu, S, Tanimura, N, Omasa, T, Suga, K, Matsumura, T

“…Glutamine synthetase (GS) is involved in an accessory pathway of ammonia removal in mammals. To develop a bioartificial liver with a human cell line, GS gene…”
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A bioreactor with glutamine synthetase-transfected recombinant HepG2 cells exhibits ammonia removal activity without the need for added cofactors and substrates: Advantage of a cellular bioreactor over enzyme-immobilized beads by Enosawa, Shin, Miyashita, Tomoyuki, Li, Xiao-Kang, Suzuki, Seiichi, Amemiya, Hiroshi, Omasa, Takeshi, Suga, Kenichi, Matsumura, Toshiharu

“…The biological efficacy of recombinant human hepatic cell line, glutamine synthetase-transfected HepG2 (GS-HepG2), was examined under various culture…”
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Coculture of hepatic and renal origin cell lines provides biohemofiltration with an active transport system of xenobiotics metabolites by Endo, Mitsufumi, Enosawa, Shin, Suzuki, Seiichi, Amemiya, Hiroshi, Tsuruoka, Shuichi, Fujimura, Akio, Hiramatsu, Shinya, Omasa, Takeshi, Suga, Kenichi, Matsumura, Toshiharu, Aoki, Tatsuya, Koyanagi, Yasuhisa

“…To improve the present bioartificial liver systems by adding the capacity for selective and active transport, recombinant hepatic GS-HepG2 and renal proximal…”
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Multilayer rat hepatocyte aggregates formed on expanded polytetrafluoroethylene surface by Tokiwa, T, Kano, J, Kodama, M, Matsumura, T

“…Feasibility of using a macroporous membrane material, expanded polytetrafluoroethylene (ePTFE), for culturing hepatocytes on its surface was examined. Adult…”
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Application of circulatory flow bioreactor for long-term and large-scale culture of glutamine synthetase transduced CHO cells and its ammonia removal activity with an aim of development for a bioartificial liver assist system by Enosawa, Shin, Mukaiyama, Toshiyuki, Miyashita, Tomoyuki, Li, Xiao-Kang, Suzuki, Seiichi, Amemiya, Hiroshi, Matsumura, Toshiharu, Omasa, Takeshi, Suga, Kenichi

“…Glutamine synthetase-transduced Chinese hamster ovary (GS-CHO) cells were cultured in a circulatory flow bioreactor for 28 days. The bioreactor inoculated with…”
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A recombinant bait region mutant of human α2-macroglobulin exhibiting an altered proteinase-inhibiting spectrum by IKAI, A, OOKATA, K, SHIMIZU, M, NAKAMICHI, N, ITO, M, MATSUMURA, T

“…Alpha 2-macroglobulin (α2M), a plasma glycoprotein produced in the liver, inhibits a variety of proteinases and thus considered to play important homeostatic…”
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Detection, Localization, and Sequence Analyses of Mitochondrial Regulatory Region RNAs in Several Mammalian Species by Nakamichi, Noboru, Rhoads, Douglas D., Hayashi, Jun-Ichi, Kagawa, Yasuo, Matsumura, Toshiharu

“…The mitochondrial regulatory region (mrr) located between the tRNAphe and tRNApro genes of mitochondrial DNA (mtDNA) is essential for regulation of replication…”
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Structure and expression of integrated hepatitis B virus genes in an HBs antigen producing human cell line (huGK-14) by Nakamichi, N, Noda, A, Yonezu, T, Koike, K, Matsumura, T

“…A human continuous cell line (huGK-14) within a lineage of passaged cultures was investigated in the mode of integration and expression of hepatitis B virus…”
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Characterization of a Strain of Mycoplasma hominis Lacking 120kDa Membrane Protein Isolated from Vero Cell Culture by SASAKI, Tsuguo, SASAKI, Yuko, MATSUMURA, Toshiharu, OYAMA, Noriko, KOSHIMIZU, Kaoru

“…A strain of Mycoplasma hominis lacking a major membrane protein of 120kDa was isolated from a Vero cell culture. This strain showed very slow growth rate and…”
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The Bioreactor With CYP3A4- and Glutamine Synthetase-Introduced HepG2 Cells: Treatment of Hepatic Failure Dog With Diazepam Overdosage by Wang, Ning, Tsuruoka, Shuichi, Yamamoto, Hisashi, Enosawa, Shin, Omasa, Takeshi, Sata, Naohiro, Matsumura, Toshiharu, Nagai, Hideo, Fujimura, Akio

“…:  A novel recombinant human hepatic cell line, CYP3A4‐ and glutamine synthetase (GS, an enzyme which converts ammonium ion and glutamate to…”
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Family Trees Representing the Finitely Proliferative Nature of Cultured Rat Liver Cells by Matsumura, Toshiharu, Masuda, Kiyofumi, Murakami, Yoshinori, Konishi, Ryuji

“…Family trees of rat liver epithelial-like cells in primary culture were obtained by cinemicrographic analysis. With few exceptions the proliferative profiles…”
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Disaggregation of connective tissue: preparation of fibrous components from sea cucumber body wall and calf skin by Matsumura, T, Shinmei, M, Nagai, Y

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Conversion of Proliferation and Production of the Colony Stimulating Factor during Serial Passage of Mouse Fibroblasts in Culture by Matsumura, Toshiharu, Miyashita, Shigeyo, Ohno, Tadao

“…Fibroblast-like cells from a BALB/c mouse embryo were propagated and transferred weekly in culture with a constant inoculation density of 5 × 103 cells/cm2. In…”
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Inactivation of myosin ATPase by condensed polysilicic acid powders by Matsumura, Y, Matsumura, T

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Polyacrylamide containing sugar residues: synthesis, characterization and cell compatibility studies by Bahulekar, Raman, Tokiwa, Takayoshi, Kano, Junko, Matsumura, Toshiharu, Kojima, Isao, Kodama, Makoto

“…Hydrophilic polyacrylamide compounds having glucose (PAAm-glucose) and galactose (PAAm-galactose) as pendent groups were synthesized from poly(acryloyl…”
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