Search Results - "Matsumoto, Shigeji"

Contribution of the activation of satellite glia in sensory ganglia to pathological pain by Takeda, Mamoru, Takahashi, Masayuki, Matsumoto, Shigeji

“…Peripheral tissue injury/inflammation can alter the properties of somatic sensory pathways, resulting in behavioral hypersensitivity and pathological and/or…”
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Expression of transient receptor potential vanilloid 1 and anoctamin 1 in rat trigeminal ganglion neurons innervating the tongue by Kanazawa, Takuya, Matsumoto, Shigeji

“…Highlights • FG retrograde labeling was used to identify the TG neurons innervating the tongue. • FG-labeled neurons were found in the mandibular division of…”
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Peripheral inflammation suppresses inward rectifying potassium currents of satellite glial cells in the trigeminal ganglia by Takeda, Mamoru, Takahashi, Masayuki, Nasu, Masanori, Matsumoto, Shigeji

“…Inflammation suppresses satellite glial inward rectifying K + (Kir) currents in the trigeminal ganglia. Kir channel may be a potential therapeutic target for…”
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Potassium Channels as a Potential Therapeutic Target for Trigeminal Neuropathic and Inflammatory Pain by Takeda, Mamoru, Tsuboi, Yoshiyuki, Kitagawa, Junichi, Nakagawa, Kazuharu, Iwata, Koichi, Matsumoto, Shigeji

“…Previous studies in several different trigeminal nerve injury/inflammation models indicated that the hyperexcitability of primary afferent neurons contributes…”
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Enhanced excitability of nociceptive trigeminal ganglion neurons by satellite glial cytokine following peripheral inflammation by Takeda, Mamoru, Tanimoto, Takeshi, Kadoi, Jun, Nasu, Masanori, Takahashi, Masayuki, Kitagawa, Junichi, Matsumoto, Shigeji

“…Peripheral nerve injury activates satellite cells to produce interleukin 1β (IL-1β) which mediates inflammation and hyperalgesia. This study investigated the…”
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Suppression of neurokinin-1 receptor in trigeminal ganglia attenuates central sensitization following inflammation by Takeda, Mamoru, Takahashi, Masayuki, Matsumoto, Shigeji

“…This study examined whether local application of a neurokinin‐1 (NK1) receptor antagonist into the trigeminal ganglia (TRGs) modulates hyperexcitability of…”
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Somatostatin enhances tooth-pulp-evoked cervical dorsal horn neuronal activity in the rat via inhibition of GABAergic interneurons by Takahashi, Masayuki, Takeda, Mamoru, Matsumoto, Shigeji

“…Highlight • Somatostatin (SST) facilitate excitability of tooth-pulp evoked C1 neurons. • SST2a receptor(R) immunoreactive C1 dorsal horn neurons co-expressed…”
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Role of rostral medulla in serotonin-induced changes of respiratory rhythm in newborn rat brainstem-spinal cord preparations by Makino, Michio, Saiki, Chikako, Ide, Ryoji, Matsumoto, Shigeji

“…Abnormalities of the serotonin (5-hydroxytryptamine, 5-HT) system may induce respiratory disorders. We examined which regions in the rostral medulla are…”
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Brain-Derived Neurotrophic Factor Enhances the Excitability of Small-Diameter Trigeminal Ganglion Neurons Projecting to the Trigeminal Nucleus Interpolaris/Caudalis Transition Zone following Masseter Muscle Inflammation by Takeda, Mamoru, Takahashi, Masayuki, Kitagawa, Junichi, Kanazawa, Takuya, Nasu, Masanori, Matsumoto, Shigeji

“…Background The trigeminal subnuclei interpolaris/caudalis transition zones (Vi/Vc) play an important role in orofacial deep pain, however, the role of primary…”
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Glial cell line-derived neurotrophic factor modulates the excitability of nociceptive trigeminal ganglion neurons via a paracrine mechanism following inflammation by Takeda, Mamoru, Takahashi, Masayuki, Hara, Norifumi, Matsumoto, Shigeji

“…Highlight ► GDNF paracrine mechanism could be important as a therapeutic target for trigeminal inflammatory hyperalgesia…”
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Suppression of ATP-induced excitability in rat small-diameter trigeminal ganglion neurons by activation of GABAB receptor by Takeda, Mamoru, Ikeda, Mizuho, Takahashi, Masayuki, Kanazawa, Takuya, Nasu, Masanori, Matsumoto, Shigeji

“…Highlight • Small-TRG neurons co-expressed immunoreactivity of P2 X3 /GABAB receptors. • GABAB receptor activation inhibits the ATP-induced excitability of TRG…”
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Iontophoretic application of an A-type potassium channel blocker to the trigeminal ganglion neurons enhances the excitability of Aδ- and C-neurons innervating the temporomandibular joint in rats by Hara, Norifumi, Takeda, Mamoru, Takahashi, Masayuki, Matsumoto, Shigeji

“…► We examined effect of 4-AP on the excitability of TRG neurons that innervate the TMJ region ► Application of 4-AP into the TRGs enhanced Aδ/C-TRG neuronal…”
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Temporomandibular joint inflammation decreases the voltage-gated K+ channel subtype 1.4-immunoreactivity of trigeminal ganglion neurons in rats by Takeda, Mamoru, Tanimoto, Takeshi, Nasu, Masanori, Matsumoto, Shigeji

“…Abstract Voltage-gated K+ (Kv) channels are one of the important physiological regulators of the membrane potentials in excitable cells, including sensory…”
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Alteration of Primary Afferent Activity following Inferior Alveolar Nerve Transection in Rats by Nakagawa, Kazuharu, Takeda, Mamoru, Tsuboi, Yoshiyuki, Kondo, Masahiro, Kitagawa, Junichi, Matsumoto, Shigeji, Kobayashi, Azusa, Sessle, Barry J, Shinoda, Masamichi, Iwata, Koichi

“…Background: In order to evaluate the neural mechanisms underlying the abnormal facial pain that may develop following regeneration of the injured inferior…”
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Activation of NK1 receptor of trigeminal root ganglion via substance P paracrine mechanism contributes to the mechanical allodynia in the temporomandibular joint inflammation in rats by Takeda, Mamoru, Tanimoto, Takeshi, Nasu, Masanori, Ikeda, Mizuho, Kadoi, Jun, Matsumoto, Shigeji

“…The aim of this study was to investigate whether under in vivo conditions, temporomandibular joint (TMJ) inflammation alters the excitability of Aβ-trigeminal…”
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Alteration of the second branch of the trigeminal nerve activity following inferior alveolar nerve transection in rats by Tsuboi, Yoshiyuki, Takeda, Mamoru, Tanimoto, Takeshi, Ikeda, Mizuho, Matsumoto, Shigeji, Kitagawa, Junichi, Teramoto, Kohei, Simizu, Kohei, Yamazaki, Yoko, Shima, Asako, Ren, Ke, Iwata, Koichi

“…After transection of the inferior alveolar nerve (IAN), the whisker pad area, which is innervated by the infraorbital nerve (ION) that was not injured, showed…”
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Temporomandibular Joint Inflammation Potentiates the Excitability of Trigeminal Root Ganglion Neurons Innervating the Facial Skin in Rats by Takeda, Mamoru, Tanimoto, Takeshi, Ikeda, Mizuho, Nasu, Masanori, Kadoi, Jun, Shima, Yukio, Ohta, Hidehiko, Matsumoto, Shigeji

“…1 Department of Physiology and 2 Research Center for Odontology, School of Dentistry at Tokyo, Nippon Dental University, Tokyo; and 3 Laboratory of…”
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Peripheral and Central Mechanisms of Trigeminal Neuropathic and Inflammatory Pain by Takeda, Mamoru, Matsumoto, Shigeji, Sessle, Barry J., Shinoda, Masamichi, Iwata, Koichi

“…While physiological pain (nociceptive pain) has a protective role in warning of potential tissue damage in response to a variety of noxious stimuli,…”
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Systemic administration of lidocaine suppresses the excitability of rat cervical dorsal horn neurons and tooth-pulp-evoked jaw-opening reflex by Takeda, Mamoru, Oshima, Katsuo, Takahashi, Masayuki, Matsumoto, Shigeji

“…Abstract Although systemic lidocaine has been demonstrated to have analgesic actions in neuropathic pain conditions, the effect of intravenous lidocaine on…”
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Glial cell line-derived neurotrophic factor acutely modulates the excitability of rat small-diameter trigeminal ganglion neurons innervating facial skin by Takeda, Mamoru, Kitagawa, Junichi, Nasu, Masanori, Takahashi, Masayuki, Iwata, Koichi, Matsumoto, Shigeji

“…Abstract Glial cell line-derived neurotrophic factor (GDNF) plays an important role in adult sensory neuron function. However, the acute effects of GDNF on…”
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