Search Results - "Matsukura, Hiroko"

Efficient strategy for the iterative synthesis of trans-fused polycyclic ether via SmI2-induced reductive intramolecular cyclization by Hori, Nobuyuki, Matsukura, Hiroko, Matsuo, Goh, Nakata, Tadashi

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Efficient Synthesis of trans-Fused Polycyclic Ethers Including Tetrahydropyrans and Oxepanes Based on SmI2-Induced Reductive Cyclization by Hori, Nobuyuki, Matsukura, Hiroko, Nakata, Tadashi

“…An efficient method for the synthesis of trans-fused polycyclic ether ring systems including tetrahydropyrans and oxepanes, i.e., six−seven−six-,…”
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An efficient strategy for the iterative synthesis of a trans-fused polytetrahydropyran ring system via SmI2-induced reductive intramolecular cyclization by Hori, Nobuyuki, Matsukura, Hiroko, Matsuo, Goh, Nakata, Tadashi

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Stereoselective Syntheses of the C‘D‘E‘F‘-Ring System of Maitotoxin and the FG-Ring System of Gambierol by Sakamoto, Yasuharu, Matsuo, Goh, Matsukura, Hiroko, Nakata, Tadashi

“…The stereoselective syntheses of the C‘D‘E‘F‘-ring system of maitotoxin and the FG-ring system of gambierol were accomplished. The key steps involve…”
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Further study on SmI2-induced reductive intramolecular cyclization: synthesis of polycyclic ethers having an angular methyl group by Suzuki, Keisuke, Matsukura, Hiroko, Matsuo, Goh, Koshino, Hiroyuki, Nakata, Tadashi

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Stereoselective synthesis of six- and seven-membered ether rings based on the ring expansion by Nakata, Tadashi, Nomura, Sumihiro, Matsukura, Hiroko

“…Six- and seven-membered ether rings were stereoselectively synthesized based on the rearrangement of the cyclic ether with the simultaneous ring expansion…”
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Synthetic studies on brevetoxin-B. Part 2: Stereoselective synthesis of the EFG-ring system by Matsuo, Goh, Hori, Nobuyuki, Matsukura, Hiroko, Nakata, Tadashi

“…The EFG-ring system of brevetoxin-B, having an α-methyl group on the D-ring, was stereoselectively synthesized based on the stereoselective Michael addition of…”
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Stereoselective Synthesis of ABC-Ring System of Hemibrevetoxin B by Matsukura, Hiroko, Morimoto, Masamichi, Nakata, Tadashi

“…The 6, 6, 7-membered tricyclic ether ring system (ABC-ring) of hemibrevetoxin B was stereoselectively synthesized. The curcial steps in the present synthesis…”
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Total Synthesis of Brevetoxin-B by Matsuo, Goh, Kawamura, Koji, Hori, Nobuyuki, Matsukura, Hiroko, Nakata, Tadashi

“…Brevetoxin-B (BTX-B), produced by the red tide organism, Gymnodium breve Davis, is the first member of marine polycyclic ethers to be structurally elucidated…”
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Enzymatic hydrolysis in organic solvents for kinetic resolution of water-insoluble α-acyloxy esters with immobilized lipases by AKITA, H, UMEZAWA, I, MATSUKURA, H

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STEREOSELECTIVE SYNTHESIS OF THE S- AND Y-RING SYSTEMS OF MAITOTOXIN by NAKATA, Tadashi, NOMURA, Sumihiro, MATSUKURA, Hiroko

“…The seven-membered S- and Y-ring systems of maitotoxin (1) were stereoselectively synthesized based on the rearrangement-ring expansion of the six-membered…”
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Synthesis of Optically Pure Norcantharidin Analogue NCA-01, a Highly Selective Protein Phosphatase 2B Inhibitor, and its Derivatives by Shimizu , Tadashi, Iizuka, Masato, Matsukura, Hiroko, Hashizume, Daisuke, Sodeoka, Mikiko

“…An efficient synthetic route to optically pure norcantharidin analogue NCA‐01, a highly selective inhibitor of protein phosphatase 2B (PP2B; calcineurin), has…”
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An Amphiphile-Lipase Aggregate Bearing 1, 2-Dialkylated Mannitol Ether as a New Type of Immobilized Enzyme in Organic Solvents by AKITA, Hiroyuki, KATO, Keisuke, UMEZAWA, Isao, MATSUKURA, Hiroko

“…Neutral amphiphiles of a new type corresponding to 1, 2-dialkylated mannitol ethers (6-10) were synthesized. Amephiphile-lipase aggregates were found to…”
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A LIPID LIPASE AGGREGATE AS A NEW TYPE OF IMMOBILIZED ENZYME by AKITA, Hiroyuki, UMEZAWA, Isao, MATSUKURA, Hiroko, OISHI, Takeshi

“…Lipid-lipase aggregate was prepared by mixing an aqueous solution of lipase with a benzene solution of synthetic phospholipids. The precipitated solid…”
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A Facile Chemoenzymatic Route to Optically Active 4, 5-Disubstituted-2E-hexenoate Derivatives. I by AKITA, Hiroyuki, UMEZAWA, Isao, TAKANO, Michika, OHYAMA, Chiiko, MATSUKURA, Hiroko, OHISHI, Takeshi

“…The reaction of (±) methyl 4, 5-trans-epoxy-2E-hexenoate (2) with aromatic nucleophiles having an electrondonating group in the presence of BF3·Et2O gave the…”
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Enantioselective Acetylation of an α-Hydroxy Ester by Using Ether-Linked Lipid-Lipase Aggregates in Organic Solvents by AKITA, Hiroyuki, UMEZAWA, Isao, TISNADJAJA, Djadjat, MATSUKURA, Hiroko, OISHI, Takeshi

“…Phospholipids of a new type having ω-cyclohexyltridecyl groups were synthesized in order to investigate the influence of the structure of lipophilic part of…”
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A Formal Total Synthesis of (-)-Oudemansin B by AKITA, Hiroyuki, MATSUKURA, Hiroko, Karashima, Hirotoshi, OISHI, Takeshi

“…(-)-Oudemansin B (1) was formally synthesized from the (2S, 3R)-3-hydroxy lactone 5 obtained by microbial asymmetric reduction as a key step…”
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A FACILE CHEMOENZYMATIC ROUTE TO ENANTIOMERICALLY PURE 4, 5-DISUBSTITUTED-2-HEXENOATE DERIVATIVES by AKITA, Hiroyuki, UMEZAWA, Isao, TAKANO, Michika, MATSUKURA, Hiroko, OISHI, Takeshi

“…The reaction of 4, 5-epoxy-2-hexenoate 2__- and various nucleophiles in the presenece of BF3.Et20 predominantly gave the (4, 5)-5-hydroxy-4-substituted…”
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The Regioselective Dehydration of Unsymmetrical Secondary Alcohols under Mitsunobu's Reaction Conditions by AKITA, Hiroyuki, YAMADA, Harutami, MATSUKURA, Hiroko, NAKATA, Tadashi, OISHI, Takeshi

“…Dehydration of the four diastereomers of tetrahydropyran 8-11 involving the 4-hydroxyl and 5-methyl groups with diethylazodicarboxylate-PPh3-toluene was…”
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SYNTHESIS OF USEFUL CHIRAL SYNTHONS (2R, 3R)-2-METHYLMALATE AND ITS CONGENERS VIA MICROBIAL ASYMMETRIC REDUCTION by Akita, Hiroyuki, Matsukura, Hiroko, Oishi, Takeshi

“…Asymmetric reduction of the commercially available diethyl 2-methyl-3-oxo-succinate 4___∼ with Candida albicans gave a mixture of (3R)-methylmalates 5___∼a and…”
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