Search Results - "Matsudaira, P"

Elastic Behavior of Cross-Linked and Bundled Actin Networks by Gardel, M. L., Shin, J. H., MacKintosh, F. C., Mahadevan, L., Matsudaira, P., Weitz, D. A.

“…Networks of cross-linked and bundled actin filaments are ubiquitous in the cellular cytoskeleton, but their elasticity remains poorly understood. We show that…”
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Scaling of F-actin network rheology to probe single filament elasticity and dynamics by GARDEL, M. L, SHIN, J. H, MACKINTOSH, F. C, MAHADEVAN, L, MATSUDAIRA, P. A, WEITZ, D. A

“…The linear and nonlinear viscoelastic response of networks of cross-linked and bundled cytoskeletal filaments demonstrates remarkable scaling with both…”
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Motility Powered by Supramolecular Springs and Ratchets by Mahadevan, L., Matsudaira, P.

“…Not all biological movements are caused by molecular motors sliding along filaments or tubules. Just as springs and ratchets can store or release energy and…”
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Relating Microstructure to Rheology of a Bundled and Cross-Linked F-Actin Network in vitro by Shin, J. H., Gardel, M. L., Mahadevan, L., Matsudaira, P., Weitz, D. A., Lubensky, Tom C.

“…The organization of individual actin filaments into higher-order structures is controlled by actin-binding proteins (ABPs). Although the biological…”
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Colloid Surface Chemistry Critically Affects Multiple Particle Tracking Measurements of Biomaterials by Valentine, M.T., Perlman, Z.E., Gardel, M.L., Shin, J.H., Matsudaira, P., Mitchison, T.J., Weitz, D.A.

“…Characterization of the properties of complex biomaterials using microrheological techniques has the promise of providing fundamental insights into their…”
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Laser-Guided Assembly of Heterotypic Three-Dimensional Living Cell Microarrays by Akselrod, G.M., Timp, W., Mirsaidov, U., Zhao, Q., Li, C., Timp, R., Timp, K., Matsudaira, P., Timp, G.

“…We have assembled three-dimensional heterotypic networks of living cells in hydrogel without loss of viability using arrays of time-multiplexed, holographic…”
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Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes by Matsudaira, P.

“…Small amounts (7-250 pmol) of myoglobin, beta-lactoglobulin, and other proteins and peptides can be spotted or electroblotted onto polyvinylidene difluoride…”
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Power-Limited Contraction Dynamics of Vorticella convallaria: An Ultrafast Biological Spring by Upadhyaya, A., Baraban, M., Wong, J., Matsudaira, P., van Oudenaarden, A., Mahadevan, L.

“…Vorticella convallaria is one of the fastest and most powerful cellular machines. The cell body is attached to a substrate by a slender stalk containing a…”
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Inhibition of energy metabolism alters the processing of amyloid precursor protein and induces a potentially amyloidogenic derivative by GABUZDA, D, BUSCIGLIO, J, LAN BO CHEN, MATSUDAIRA, P, YANKNER, B. A

“…The cellular mechanisms which lead to the generation and pathological deposition of beta amyloid in Alzheimer's disease are unknown. In this report we describe…”
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Calcium Regulation of an Actin Spring by Tam, Barney K., Shin, Jennifer H., Pfeiffer, Emily, Matsudaira, P., Mahadevan, L.

“…Calcium is essential for many biological processes involved in cellular motility. However, the pathway by which calcium influences motility, in processes such…”
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A Closed-Cycle Capillary Polymerase Chain Reaction Machine by Chiou, Jeff, Matsudaira, Paul, Sonin, Ain, Ehrlich, Daniel

“…A novel thermocycling machine based on a microcapillary equipped with bidirectional pressure-driven flow and in situ optical position sensors is described. A…”
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Three-Dimensional Network Photonic Crystals via Cyclic Size Reduction/ Infiltration of Sea Urchin Exoskeleton by Ha, Y.-H., Vaia, R. A., Lynn, W. F., Costantino, J. P., Shin, J., Smith, A. B., Matsudaira, P. T., Thomas, E. L.

“…A reduction and infiltration process for a naturally occurring 3D bicontinuous structure is demonstrated. A sea urchin exoskeleton can be engineered in a…”
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Microchip electrophoresis: a method for high-speed SNP detection by Schmalzing, D, Belenky, A, Novotny, M A, Koutny, L, Salas-Solano, O, El-Difrawy, S, Adourian, A, Matsudaira, P, Ehrlich, D

“…As a trial practical application, we have applied optimized microfabricated electrophoresis devices, combined with enzymatic mutation detection methods, to the…”
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Generation of β-Amyloid in the Secretory Pathway in Neuronal and Nonneuronal Cells by Busciglio, Jorge, Gabuzda, Dana H., Matsudaira, Paul, Yankner, Bruce A.

“…The cellular mechanism underlying the generation of β-amyloid in Alzheimer disease and its relationship to the normal metabolism of the amyloid precursor…”
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The COOH Terminus of the c-Abl Tyrosine Kinase Contains Distinct F- and G-Actin Binding Domains with Bundling Activity by Van Etten, Richard A., Jackson, Peter K., Baltimore, David, Sanders, Mitchell C., Matsudaira, Paul T., Janmey, Paul A.

“…The myristoylated form of c-Abl protein, as well as the P210bcr/abl protein, have been shown by indirect immunofluorescence to associate with F-actin stress…”
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Relative Distribution of Actin, Myosin I, and Myosin II during the Wound Healing Response of Fibroblasts by Conrad, Patricia A., Giuliano, Kenneth A., Fisher, Greg, Collins, Kathleen, Matsudaira, Paul T., Taylor, D. Lansing

“…Myosin I is present in Swiss 3T3 fibroblasts and its localization reflects a possible involvement in the extension and/or retraction of protrusions at the…”
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Study of cell-cell signaling in 3D bacterial arrays assembled using optical tweezers by Mirsaidov, U, Timp, W, Mir, M, Matsudaira, P, Timp, G

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NMR structure of the 35-residue villin headpiece subdomain by McKnight, C. James, Matsudaira, Paul T, Kim, Peter S

“…The NMR structure of an autonomously folding subdomain from villin headpiece is reported. It forms a novel three helix structure with the actin-binding…”
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Direct protein microsequencing from Immobilon-P Transfer Membrane by LeGendre, N, Matsudaira, P

“…Proteins separated by electrophoresis and electroblotted onto Immobilon-P Transfer Membrane can be sequenced directly in the gas-phase sequencer. Protein bands…”
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Shear-Induced Degradation of Linear Polyacrylamide Solutions during Pre-Electrophoretic Loading by Vazquez, Maribel, Schmalzing, Dieter, Matsudaira, Paul, Ehrlich, Daniel, McKinley, Gareth

“…Electrophoretic channels are filled with a polymer matrix prior to their use in DNA separations. This process, called gel-loading, can be accomplished…”
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