Search Results - "Matsubara, Osamu"

PIK3CA mutation is an early event in the development of endometriosis-associated ovarian clear cell adenocarcinoma by Yamamoto, Sohei, Tsuda, Hitoshi, Takano, Masashi, Iwaya, Keichi, Tamai, Seiichi, Matsubara, Osamu

“…Clear cell adenocarcinoma (CCA), a highly lethal histological subtype of ovarian carcinoma, is a type of human cancer with a high frequency of activating…”
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Is the epidermal growth factor receptor status in lung cancers reflected in clinicopathologic features? by Inamura, Kentaro, Ninomiya, Hironori, Ishikawa, Yuichi, Matsubara, Osamu

“…Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors are molecular-targeted drugs that are innovatively effective for non-small cell lung…”
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PIK3CA mutations and loss of ARID1A protein expression are early events in the development of cystic ovarian clear cell adenocarcinoma by Yamamoto, Sohei, Tsuda, Hitoshi, Takano, Masashi, Tamai, Seiichi, Matsubara, Osamu

“…Somatic mutations of PIK3CA and ARID1A are the most common genetic alterations observed in ovarian clear cell adenocarcinomas (CCA). In a previous report, we…”
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Pulmonary Tumor Thrombotic Microangiopathy with Circulatory Failure Treated with Imatinib by Ogawa, Aiko, Yamadori, Ichiro, Matsubara, Osamu, Matsubara, Hiromi

“…Pulmonary tumor thrombotic microangiopathy is a lethal, yet difficult to diagnose, complication of gastrointestinal carcinoma. Even if properly diagnosed,…”
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An autopsy case of acute fibrinous and organizing pneumonia with periorbital MRSA cellulitis and rheumatoid arthritis by Hara, Akihiro, Kishimoto, Yutaro, Shirai, Toshihiro, Murakami, Akinori, Suzuki, Makoto, Matsubara, Osamu

“…This case report details a 78‐year‐old male with periorbital Methicillin‐resistant Staphylococcus aureus (MRSA) cellulitis whose condition rapidly deteriorated…”
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Acute fibrinous and organizing pneumonia in systemic lupus erythematosus: A case report and review of the literature by Hariri, Lida P., Unizony, Sebastian, Stone, John, Mino‐Kenudson, Mari, Sharma, Amita, Matsubara, Osamu, Mark, Eugene J.

“…Pulmonary manifestations of systemic lupus erythematosus (SLE) typically include pleuritis, alveolar hemorrhage, and infectious pneumonia due to…”
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Distinct histopathology of acute onset or abrupt exacerbation of hypersensitivity pneumonitis by Hariri, Lida P., MD, PhD, Mino-Kenudson, Mari, MD, Shea, Barry, MD, Digumarthy, Subba, MD, Onozato, Maristela, MD, PhD, Yagi, Yukako, PhD, Fraire, Armando E., MD, Matsubara, Osamu, MD, Mark, Eugene J., MD

“…Summary Hypersensitivity pneumonitis is an inflammatory lung disease that develops in response to exposure to antigen. Cases can be stratified by the duration…”
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High levels of DJ‐1 protein and isoelectric point 6.3 isoform in sera of breast cancer patients by Kawate, Takahiko, Iwaya, Keiichi, Koshikawa, Kayoko, Moriya, Tomoyuki, Yamasaki, Tamio, Hasegawa, Sho, Kaise, Hiroshi, Fujita, Tomoyuki, Matsuo, Hirotaka, Nakamura, Takahiro, Ishikawa, Takashi, Hiroi, Sadayuki, Iguchi‐Ariga, Sanae M.M., Ariga, Hiroyoshi, Murota, Keiichi, Fujimori, Minoru, Yamamoto, Junji, Matsubara, Osamu, Kohno, Norio

“…In patients with cancer and Parkinson's disease, the DJ‐1 protein may be secreted into the serum during the impaired response of the underlying cell‐protective…”
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Array comparative genomic hybridization analysis discloses chromosome copy number alterations as indicators of patient outcome in lymph node-negative breast cancer by Kikuchi-Koike, Ryoko, Nagasaka, Kazunori, Tsuda, Hitoshi, Ishii, Yasuyuki, Sakamoto, Masaru, Kikuchi, Yoshihiro, Fukui, Shiho, Miyagawa, Yuko, Hiraike, Haruko, Kobayashi, Takayuki, Kinoshita, Takayuki, Kanai, Yae, Shibata, Tatsuhiro, Imoto, Issei, Inazawa, Johji, Matsubara, Osamu, Ayabe, Takuya

“…Patients with lymph node metastasis-negative (pN0) invasive breast cancer have favorable outcomes following initial treatment. However, false negatives which…”
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Pleuroparenchymal Fibroelastosis as a Series of Airway Complications Associated with Chronic Graft-versus-host Disease following Allogeneic Bone Marrow Transplantation by Fujikura, Yuji, Kanoh, Soichiro, Kouzaki, Yuji, Hara, Yu, Matsubara, Osamu, Kawana, Akihiko

“…We herein report the case of a 31-year-old woman who presented with bilateral upper lobe volume loss and pleural irregularities with hilar retraction. She had…”
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A case of synchronous multiple primary lung adenocarcinomas harboring epidermal growth factor receptor mutation and anaplastic lymphoma kinase rearrangement successfully treated with combination of osimertinib and alectinib by Inoue, Yukihisa, Matsubara, Osamu, Ohira, Yumi, Endo, Satoshi, Jinn, Yasuto

“…Synchronous multiple primary lung cancers (SMPLC) should be distinguished from intrapulmonary metastasis to define the optimal treatment approach. Epidermal…”
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Expanded acceptance of acute exacerbation of nonspecific interstitial pneumonia, including 7 additional cases with detailed clinical pathologic correlation by Miyamoto, Atsushi, Sharma, Amita, Nishino, Michiya, Mino‐Kenudson, Mari, Matsubara, Osamu, Mark, Eugene Jerome

“…Acute exacerbation is uncommonly diagnosed in patients with nonspecific interstitial pneumonia (NSIP) and its pathologic features have received relatively…”
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Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis by Shuda, Masahiro, Kondoh, Nobuo, Imazeki, Nobuo, Tanaka, Kenji, Okada, Tetsuya, Mori, Kazutoshi, Hada, Akiyuki, Arai, Masaaki, Wakatsuki, Toru, Matsubara, Osamu, Yamamoto, Naoki, Yamamoto, Mikio

“…Background/Aims: We identified the glucose-regulated protein (grp) 78 as a transformation-associated gene in hepatocellular carcinoma (HCC). Grp78 is a…”
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Clinical significance of DJ-1 as a secretory molecule: retrospective study of DJ-1 expression at mRNA and protein levels in ductal carcinoma of the breast by Tsuchiya, Benio, Iwaya, Keiichi, Kohno, Norio, Kawate, Takahiko, Akahoshi, Tohru, Matsubara, Osamu, Mukai, Kiyoshi

“…Tsuchiya B, Iwaya K, Kohno N, Kawate T, Akahoshi T, Matsubara O & Mukai K 
(2012) Histopathology 61, 69–77 Clinical significance of DJ‐1 as a secretory…”
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Accumulative copy number increase of MET drives tumor development and histological progression in a subset of ovarian clear-cell adenocarcinomas by Yamamoto, Sohei, Tsuda, Hitoshi, Miyai, Kosuke, Takano, Masashi, Tamai, Seiichi, Matsubara, Osamu

“…Our previous study demonstrated that, among ovarian carcinomas, amplification of the MET gene and overexpression of MET specifically and commonly occur in…”
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Solitary Cardiac Metastasis from Colorectal Cancer: A Case Report by Numata, Koji, Urata, Nozomi, Nakayama, Yuta, Ju, Mihwa, Tanaka, Ayano, Nakayama, Hirotaka, Yamanaka, Kazuki, Hatori, Shinsuke, Matsubara, Osamu, Rino, Yasushi, Tani, Kazuyuki

“…A 73-year-old woman with silent cardiac metastasis underwent high anterior resection for rectal cancer 3 years ago. Follow-up computed tomography showed a…”
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Hyperprogressive disease after treatment with pembrolizumab in lung adenocarcinoma: An autopsy case study by Tanaka, Yuko, Matsubara, Osamu, Asada, Kazuhiro, Muramatsu, Aya, Suzuki, Makoto, Shirai, Toshihiro

“…Although immune-checkpoint inhibitors (ICIs) have become an important choice of treatment for advanced NSCLC, recent reports show hyperprogressive disease…”
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A case of diffuse large B‐cell lymphoma originating from chest wall complicated by benign asbestos pleural effusion by Kondo, Nobuyuki, Inoue, Yukihisa, Takeyama, Hiroaki, Kobayashi, Akiko, Matsubara, Osamu, Jinn, Yasuto

“…A 78‐year‐old man with exposure to asbestos was admitted to our hospital for back pain. A chest computed tomography showed right pleural effusion and a…”
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High levels of DJ‐1 protein in nipple fluid of patients with breast cancer by Oda, Miki, Makita, Masujiro, Iwaya, Keiichi, Akiyama, Futoshi, Kohno, Norio, Tsuchiya, Benio, Iwase, Takuji, Matsubara, Osamu

“…As we have previously demonstrated that some breast cancer cell lines secrete DJ‐1 protein, we examined here whether breast cancer cells secrete DJ‐1 protein…”
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The expression and clinical significance of connective tissue growth factor in advanced head and neck squamous cell cancer by Kikuchi, Ryoko, Kikuchi, Yoshihiro, Tsuda, Hitoshi, Maekawa, Hitoshi, Kozaki, Ken-ichi, Imoto, Issei, Tamai, Seiichi, Shiotani, Akihiro, Iwaya, Keiichi, Sakamoto, Masaru, Sekiya, Takao, Matsubara, Osamu

“…Connective tissue growth factor (CTGF) has been reported to play critical roles in the tumorigenesis of several human malignancies. This study was performed to…”
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