Search Results - "Matsson, Elin"

Novel Relaxin Receptor RXFP1 Agonist AZD3427 in the Treatment of Heart Failure: A Phase 1a/b, First-in-Human, Randomized, Single-Blind, Placebo-Controlled Study by Connolly, Kathleen, George, Richard, Omar, Sami, Matsson, Elin, Åstrand, Magnus, Althage, Magnus, Pettersen, Daniel, Mohamed, Esha, Fang, Kelly, Lima, Joao A C, Kujacic, Mirjana, Ödesjö, Helena, Turton, Michelle, Johannesson, Petra, Gabrielsen, Anders, Ufnal, Marcin

“…Heart failure mortality remains high despite recent progress in pharmacological treatment. AZD3427 is a selective long-acting analog of relaxin, a vasodilatory…”
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Effect of a Single Gemfibrozil Dose on the Pharmacokinetics of Rosuvastatin in Bile and Plasma in Healthy Volunteers by Bergman, Ebba, Matsson, Elin M., Hedeland, Mikael, Bondesson, Ulf, Knutson, Lars, Lennernäs, Hans

“…The effect of a single intrajejunal dose of gemfibrozil (600 mg) on the plasma pharmacokinetics and biliary excretion of a single intrajejunal dose of…”
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Combined in Vitro–in Vivo Approach To Assess the Hepatobiliary Disposition of a Novel Oral Thrombin Inhibitor by Matsson, Elin M, Eriksson, Ulf G, Palm, Johan E, Artursson, Per, Karlgren, Maria, Lazorova, Lucia, Brännström, Marie, Ekdahl, Anja, Dunér, Kristina, Knutson, Lars, Johansson, Susanne, Schützer, Kajs-Marie, Lennernäs, Hans

“…Two clinical trials and a large set of in vitro transporter experiments were performed to investigate if the hepatobiliary disposition of the direct thrombin…”
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Effects of Ketoconazole on the In Vivo Biotransformation and Hepatobiliary Transport of the Thrombin Inhibitor AZD0837 in Pigs by MATSSON, Elin M, PALM, Johan E, ERIKSSON, Ulf G, BOTTNER, Pernilla, LUNDAHL, Anna, KNUTSON, Lars, LENNERNÄS, Hans

“…Ketoconazole has been shown in clinical trials to increase the plasma exposure of the oral anticoagulant prodrug AZD0837 [(2S)-N-{4-…”
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Biliary Excretion of Ximelagatran and Its Metabolites and the Influence of Erythromycin Following Intraintestinal Administration to Healthy Volunteers by Matsson, Elin M., Eriksson, Ulf G., Knutson, Lars, Hoffmann, Kurt-Jürgen, Logren, Ulrika, Fridblom, Patrik, Petri, Niclas, Lennernäs, Hans

“…The biliary excretion of the oral thrombin inhibitor ximelagatran and its metabolites was investigated by using duodenal aspiration in healthy volunteers…”
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