Search Results - "Mats A. A. Persson"
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Identification of a Third Human Polyomavirus
Published in Journal of Virology (01-04-2007)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The disulfide bonds in glycoprotein E2 of hepatitis C virus reveal the tertiary organization of the molecule
Published in PLoS pathogens (01-02-2010)“…Hepatitis C virus (HCV), a major cause of chronic liver disease in humans, is the focus of intense research efforts worldwide. Yet structural data on the viral…”
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3
Tumor-Specific Bacteriophages Induce Tumor Destruction through Activation of Tumor-Associated Macrophages
Published in The Journal of immunology (1950) (01-03-2009)“…We recently reported that administration of tumor-specific bacteriophages initiates infiltration of neutrophilic granulocytes with subsequent regression of…”
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Human combinatorial libraries yield rare antibodies that broadly neutralize hepatitis C virus
Published in Proceedings of the National Academy of Sciences - PNAS (09-10-2007)“…One way to dissect the antibody response to an invading microorganism is to clone the antibody repertoire from immune donors and subsequently characterize the…”
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Dual topology of the processed hepatitis C virus protein NS4B is influenced by the NS5A protein
Published in Journal of general virology (01-11-2006)“…1 Karolinska Institutet, Department of Medicine at Center for Molecular Medicine (L8 : 01), Karolinska University Hospital Solna, S-171 76 Stockholm, Sweden 2…”
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Migration and Differentiation of Neural Precursor Cells Can Be Directed by Microglia
Published in Proceedings of the National Academy of Sciences - PNAS (23-12-2003)“…Recent reports have supported the existence of neural stem cells in the adult mammalian CNS. Important features of such cells are self-renewal and…”
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Efficient reprogramming of adult neural stem cells to monocytes by ectopic expression of a single gene
Published in Proceedings of the National Academy of Sciences - PNAS (17-08-2010)“…Neural stem cells have a broad differentiation repertoire during embryonic development and can be reprogrammed to pluripotency comparatively easily. We report…”
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8
Topology of the Membrane-Associated Hepatitis C Virus Protein NS4B
Published in Journal of Virology (01-05-2003)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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9
Tumor specific phage particles promote tumor regression in a mouse melanoma model
Published in CANCER IMMUNOLOGY IMMUNOTHERAPY (01-05-2007)“…Within cancer research, phage display libraries have been widely used for the identification of tumor targeting peptides and antibodies. Additionally, phages…”
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Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity
Published in Nature communications (20-12-2016)“…Comprehensive knowledge of immunoglobulin genetics is required to advance our understanding of B cell biology. Validated immunoglobulin variable (V) gene…”
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High-level secretion of recombinant monomeric murine and human single-chain Fv antibodies from Drosophila S2 cells
Published in Protein engineering, design and selection (01-02-2012)“…Single-chain variable fragment (scFvs) antibodies are small polypeptides (∼26 kD) containing the heavy (VH) and light (VL) immunoglobulin domains of a parent…”
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Twenty years of combinatorial antibody libraries, but how well do they mimic the immunoglobulin repertoire?
Published in Proceedings of the National Academy of Sciences - PNAS (01-12-2009)Get full text
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Efficient expression of recombinant human monoclonal antibodies in Drosophila S2 cells
Published in Journal of immunological methods (10-01-2007)“…We have explored the Drosophila S2 cell line for expression of Ig molecules isolated as Fab or scFv cDNA from phage-displayed libraries. We present a series of…”
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A Diverse Panel of Hepatitis C Virus Glycoproteins for Use in Vaccine Research Reveals Extremes of Monoclonal Antibody Neutralization Resistance
Published in Journal of virology (2016)“…Despite significant advances in the treatment of hepatitis C virus (HCV) infection, the need to develop preventative vaccines remains. Identification of the…”
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Efficient method for production of high yields of Fab fragments in Drosophila S2 cells
Published in Protein engineering, design and selection (01-04-2010)“…Fab molecules are used as therapeutic agents, and are invaluable tools in structural biology. We report here a method for production of recombinant Fab in…”
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Recombinant human monoclonal antibodies against different conformational epitopes of the E2 envelope glycoprotein of hepatitis C virus that inhibit its interaction with CD81
Published in Journal of general virology (01-10-2000)“…Karolinska Institute, Department of Medicine 1 and Department of Laboratory Medicine 2 , Center for Molecular Medicine (L8:01), Karolinska Hospital, S-171 76…”
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Development and characterization of a human monoclonal antibody targeting the N-terminal region of hepatitis C virus envelope glycoprotein E1
Published in Virology (New York, N.Y.) (15-01-2018)“…Monoclonal antibodies (mAbs) targeting the hepatitis C virus (HCV) envelope have been raised mainly against envelope protein 2 (E2), while the antigenic…”
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Mutations of the Hepatitis C virus protein NS4B on either side of the ER membrane affect the efficiency of subgenomic replicons
Published in Virus research (01-11-2006)“…The non-structural protein NS4B of the Hepatitis C virus (HCV) is an integral membrane protein located in the endoplasmic reticulum (ER). Although the function…”
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Genetic variations in a well conserved 5′-untranslated region of hepatitis C virus genome isolated in Pakistan
Published in Journal of virological methods (01-09-2009)“…The diversity and extent of sequence variations between hepatitis C virus (HCV) isolates from Pakistan were studied and the probable effects of these…”
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Fluorescent protein pair emit intracellular FRET signal suitable for FACS screening
Published in Biochemical and biophysical research communications (12-01-2007)“…The fluorescent proteins ECFP and HcRed were shown to give an easily resolved FRET-signal when expressed as a fusion inside mammalian cells. HeLa-tat cells…”
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