Search Results - "Matos, Maria"

Chromone: A Valid Scaffold in Medicinal Chemistry by Gaspar, Alexandra, Matos, Maria João, Garrido, Jorge, Uriarte, Eugenio, Borges, Fernanda

“…Gaspar et al examine chromone with regard to medicinal chemistry…”
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Current Trends and Challenges in the Clinical Translation of Nanoparticulate Nanomedicines: Pathways for Translational Development and Commercialization by Hua, Susan, de Matos, Maria B C, Metselaar, Josbert M, Storm, Gert

“…The use of nanotechnology in medicine has the potential to have a major impact on human health for the prevention, diagnosis, and treatment of diseases. One…”
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Trending Topics on Coumarin and Its Derivatives in 2020 by Carneiro, Aitor, Matos, Maria João, Uriarte, Eugenio, Santana, Lourdes

“…Coumarins are naturally occurring molecules with a versatile range of activities. Their structural and physicochemical characteristics make them a privileged…”
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Coumarin and Its Derivatives—Editorial by Matos, Maria João

“…Coumarins are widely distributed in nature and can be found in a large number of naturally occurring and synthetic bioactive molecules [...]…”
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Instability Mechanisms of Water-in-Oil Nanoemulsions with Phospholipids: Temporal and Morphological Structures by Sommerling, Jan-Hendrik, de Matos, Maria B. C, Hildebrandt, Ellen, Dessy, Alberto, Kok, Robbert Jan, Nirschl, Hermann, Leneweit, Gero

“…Many food preparations, pharmaceuticals, and cosmetics use water-in-oil (W/O) emulsions stabilized by phospholipids. Moreover, recent technological…”
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Oxidation-labile linkers for controlled drug delivery by Carneiro, Aitor, Santana, Lourdes, Matos, Maria João

“…[Display omitted] The continuous symbiosis throughout chemical biology and drug discovery has led to the design of innovative bifunctional molecules for…”
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Dimethyl fumarate and monoethyl fumarate exhibit differential effects on KEAP1, NRF2 activation, and glutathione depletion in vitro by Brennan, Melanie S, Matos, Maria F, Li, Bing, Hronowski, Xiaoping, Gao, Benbo, Juhasz, Peter, Rhodes, Kenneth J, Scannevin, Robert H

“…Delayed-release dimethyl fumarate (also known as gastro-resistant dimethyl fumarate), an oral therapeutic containing dimethyl fumarate (DMF) as the active…”
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Comparative Emulsifying Properties of Octenyl Succinic Anhydride (OSA)-Modified Starch: Granular Form vs Dissolved State by Matos, María, Marefati, Ali, Gutiérrez, Gemma, Wahlgren, Marie, Rayner, Marilyn

“…The emulsifying ability of OSA-modified and native starch in the granular form, in the dissolved state and a combination of both was compared. This study aims…”
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Combined emulsifying capacity of polysaccharide particles of different size and shape by Matos, María, Marefati, Ali, Bordes, Romain, Gutiérrez, Gemma, Rayner, Marilyn

“…•Pickering emulsions were prepared combining different polysaccharide particles.•Emulsifying capacity of starch granules and cellulose nanocrystals were…”
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Interventions to Prevent Aspiration Pneumonia in Older Adults: An Updated Systematic Review by Santos, Joana M. L. G, Ribeiro, Óscar, Jesus, Luis M. T, Matos, Maria Assunção C

“…Purpose: The aim of the study was to provide an updated systematic review of randomized controlled trials that studied the effectiveness of pharmacological and…”
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Novel 2-pheynlbenzofuran derivatives as selective butyrylcholinesterase inhibitors for Alzheimer’s disease by Kumar, Amit, Pintus, Francesca, Di Petrillo, Amalia, Medda, Rosaria, Caria, Paola, Matos, Maria João, Viña, Dolores, Pieroni, Enrico, Delogu, Francesco, Era, Benedetta, Delogu, Giovanna L., Fais, Antonella

“…Alzheimer’s disease (AD) is a neurodegenerative disorder representing the leading cause of dementia and is affecting nearly 44 million people worldwide. AD is…”
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Treating neurodegenerative diseases with multitarget drugs: an interview with Maria João Matos by Matos, Maria João

“…Neurodegenerative diseases are one of the leading causes of death, disability and dependency worldwide. Since the etiology of these complex pathologies is not…”
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A New Class of Benzo[ b ]thiophene-chalcones as Cholinesterase Inhibitors: Synthesis, Biological Evaluation, Molecular Docking and ADME Studies by Delogu, Giovanna Lucia, Begala, Michela, Matos, Maria João, Crucitti, Davide, Sogos, Valeria, Era, Benedetta, Fais, Antonella

“…In this study, heterocyclic compounds containing a benzothiophene scaffold were designed and synthetized, and their inhibitory activity against cholinesterases…”
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Potential pharmacological uses of chalcones: a patent review (from June 2011 - 2014) by Matos, Maria João, Vazquez-Rodriguez, Saleta, Uriarte, Eugenio, Santana, Lourdes

“…Chalcones are one of the major classes of naturally occurring compounds. A large number of synthetic routes have been reported for the synthesis of chalcones,…”
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Chemo- and Regioselective Lysine Modification on Native Proteins by Matos, Maria J, Oliveira, Bruno L, Martínez-Sáez, Nuria, Guerreiro, Ana, Cal, Pedro M. S. D, Bertoldo, Jean, Maneiro, María, Perkins, Elizabeth, Howard, Julie, Deery, Michael J, Chalker, Justin M, Corzana, Francisco, Jiménez-Osés, Gonzalo, Bernardes, Gonçalo J. L

“…Site-selective chemical conjugation of synthetic molecules to proteins expands their functional and therapeutic capacity. Current protein modification methods,…”
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Coumarin versus Chromone Monoamine Oxidase B Inhibitors: Quo Vadis? by Fonseca, André, Reis, Joana, Silva, Tiago, Matos, Maria João, Bagetta, Donatella, Ortuso, Francesco, Alcaro, Stefano, Uriarte, Eugenio, Borges, Fernanda

“…Because of the lack of significant disease-modifying drugs for neurodegenerative disorders, a pressing need for new chemical entities endowed with IMAO-B still…”
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Cytotoxic Evaluation of Phenolic Compounds from Lichens against Melanoma Cells by Brandão, Luiz Fabrício Gardini, Alcantara, Glaucia Braz, Maria de Fátima Cepa Matos, Bogo, Danielle, Freitas, Deisy dos Santos, Oyama, Nathália Mitsuko, Honda, Neli Kika

“…Atranorin, lichexanthone, and the (+)-usnic, diffractaic, divaricatic, perlatolic, psoromic, protocetraric, and norstictic acids isolated from the lichens…”
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Study of coumarin-resveratrol hybrids as potent antioxidant compounds by Matos, Maria J, Mura, Francisco, Vazquez-Rodriguez, Saleta, Borges, Fernanda, Santana, Lourdes, Uriarte, Eugenio, Olea-Azar, Claudio

“…In the present work we synthesized a selected series of hydroxylated 3-phenylcoumarins 5-8, with the aim of evaluating in detail their antioxidant properties…”
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PEGylated PLGA Nanoparticles As a Smart Carrier to Increase the Cellular Uptake of a Coumarin-Based Monoamine Oxidase B Inhibitor by Fernandes, Carlos, Martins, Cláudia, Fonseca, André, Nunes, Rute, Matos, Maria João, Silva, Renata, Garrido, Jorge, Sarmento, Bruno, Remião, Fernando, Otero-Espinar, Francisco J, Uriarte, Eugenio, Borges, Fernanda

“…Despite research efforts to discover new drugs for Parkinson treatment, the majority of candidates fail in preclinical and clinical trials due to inadequate…”
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Predicting longevity responses to dietary restriction: A stepping stone toward precision geroscience by Perez-Matos, Maria C, Mair, William B

“…About the Authors: Maria C. Perez-Matos Affiliation: Department of Molecular Metabolism, Harvard T. H. Chan School of Public Health, Boston, Massachusetts,…”
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