Search Results - "Maton, William"

Efficient method to prepare diethylphosphonacetamides by Scaravelli, Federico, Bacchi, Sergio, Massari, Luca, Curcuruto, Ornella, Westerduin, Pieter, Maton, William

“…An efficient and versatile synthetic method is described to synthesize diethylphosphonacetamides in a single step. An efficient and versatile synthetic method…”
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An Efficient Scalable Route for the Synthesis of Enantiomerically Pure tert-Butyl-(1R,4S,6R)-4-(hydroxymethyl)-3-azabicyclo[4.1.0]heptane-3-carboxylate by Maton, William M, Stazi, Federica, Manzo, Angelo Maria, Pachera, Roberta, Ribecai, Arianna, Stabile, Paolo, Perboni, Alcide, Giubellina, Nicola, Bravo, Fernando, Castoldi, Damiano, Provera, Stefano, Turco, Lucilla, Bryant, Simon, Westerduin, Pieter, Profeta, Roberto, Nalin, Arnaldo, Miserazzi, Emanuele, Spada, Simone, Mingardi, Anna, Mattioli, Mario, Andreotti, Daniele

“…An efficient scalable route to synthesize the enantiomerically pure tert-butyl-(1R,4S,6R)-4-(hydroxymethyl)-3-azabicyclo[4.1.0]heptane-3-carboxylate is…”
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Synthesis and glycosidase inhibitory activity of enantiopure polyhydroxylated octahydroindoles and decahydroquinolines, analogs to castanospermine by Gravier-Pelletier, Christine, Maton, William, Bertho, Gildas, Le Merrer, Yves

“…The synthesis of new enantiopure polyhydroxylated octahydroindoles and decahydroquinolines, analogs to castanospermine, via a double reductive amination of…”
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Process Development of Bersacapavir, Part 2. Early Game Route Selection: Catalytic versus Stoichiometric Haloform-Type Amidation by Medina, Florian, Maton, William M., Bongartz, Jean-Pierre, Kossler, David, Eriksson, Magnus, Weerts, Johan, Peeters, Micha, Wegsteen, Koen, Keppens, Els

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Process Development of Bersacapavir, Part 1: Route Scouting Effort toward a Key Amide Intermediate by Medina, Florian, Maton, William M., Weerts, Johan, Eriksson, Magnus, Bongartz, Jean-Pierre, Clemens, Kurt, Kossler, David, Peeters, Micha, Wegsteen, Koen, Maes, Tor, Keppens, Els

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High-Throughput Experimentation Enabling Rapid Process Optimization of an RSV Drug Candidate by Jusseau, Xavier, Cleator, Ed, Maton, William M., Chen, Qinghao, Geertman, Robert, Yuan, Yuanyuan, Wang, Xiaowei, Wei, Haojuan, Medina, Florian, Giannerini, Massimo

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A Mechanistic Insight into a Simple C−N Bond Formation via SN2 Displacement: A Synergistic Kinetics and Design of Experiment Approach by Massari, Luca, Panelli, Laura, Hughes, Mark, Stazi, Federica, Maton, William, Westerduin, Pieter, Scaravelli, Federico, Bacchi, Sergio

“…A novel series of 1,2,4-triazol-3-yl-azabicyclo[3.1.0]hexanes was recently identified as new highly potent and selective dopamine (DA) D3 receptor antagonists…”
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Application of the Quality by Design Principles for the Development of the Crystallization Process for a Piperazinyl-Quinoline and Definition of the Control Strategy for Form 1 by Cimarosti, Zadeo, Rossi, Sara, Tramarin, Davide, Laval, Gilles, Stabile, Paolo, Giubellina, Nicola, Maton, William, Allieri, Brigida, Campi, Francesca, Cooke, Jason, Westerduin, Pieter

“…The studies carried out to develop a robust crystallization method for the substituted piperazinyl-quinoline (1) a compound potentially active in the treatment…”
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A Mechanistic Insight into a Simple C−N Bond Formation via S N 2 Displacement: A Synergistic Kinetics and Design of Experiment Approach by Massari, Luca, Panelli, Laura, Hughes, Mark, Stazi, Federica, Maton, William, Westerduin, Pieter, Scaravelli, Federico, Bacchi, Sergio

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Synthesis and glycosidase inhibitory activity of aminocyclitols with a C6- or a C7-ring by Gravier-Pelletier, Christine, Maton, William, Dintinger, Thierry, Tellier, Charles, Le Merrer, Yves

“…The synthesis of carbasugars and various aminocyclitols, related to voglibose and acarbose used in the treatment of non-insulino-dependant diabetes, is…”
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Route Selection and Process Development for a 5-Piperazinylquinaldine Derivative for the Treatment of Depression and Anxiety by Cimarosti, Zadeo, Giubellina, Nicola, Stabile, Paolo, Laval, Gilles, Tinazzi, Francesco, Maton, William, Pachera, Roberta, Russo, Paola, Moretti, Ramona, Rossi, Sara, Cooke, Jason W. B., Westerduin, Pieter

“…1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-imidazolidinone, 1, was identified as a potential drug for the treatment of depression and…”
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New azadisaccharide analogs as potential antidiabetics by Gravier-Pelletier, Christine, Maton, William, Le Merrer, Yves

“…The synthesis of various aminocyclitols displaying a N-substituted (or unsubstituted) polyhydroxycyclohexylamine structure is described. The strategy relies on…”
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Efficient access to azadisaccharide analogues by Gravier-Pelletier, Christine, Maton, William, Lecourt, Thomas, Le Merrer, Yves

“…The synthesis of various aminocyclitols as pseudo-azadisaccharide candidates for glycosidase inhibition is described. The strategy involves the reductive…”
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Some Remarks on the Medicinal Properties of Ledum Palustre by Maton, William George

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