Search Results - "Mato, R"
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Ibrutinib–Rituximab or Chemoimmunotherapy for Chronic Lymphocytic Leukemia
Published in The New England journal of medicine (01-08-2019)“…Patients 70 years of age or younger with previously untreated CLL were randomly assigned to receive ibrutinib plus rituximab or chemoimmunotherapy with…”
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Long-term outcomes for ibrutinib-rituximab and chemoimmunotherapy in CLL: updated results of the E1912 trial
Published in Blood (14-07-2022)“…Herein, we present the long-term follow-up of the randomized E1912 trial comparing the long-term efficacy of ibrutinib-rituximab (IR) therapy to fludarabine,…”
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Toxicities and outcomes of 616 ibrutinib-treated patients in the United States: a real-world analysis
Published in Haematologica (Roma) (01-05-2018)“…Clinical trials that led to ibrutinib's approval for the treatment of chronic lymphocytic leukemia showed that its side effects differ from those of…”
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Ibrutinib for patients with relapsed or refractory chronic lymphocytic leukaemia with 17p deletion (RESONATE-17): a phase 2, open-label, multicentre study
Published in The lancet oncology (01-10-2016)“…Summary Background The TP53 gene, encoding tumour suppressor protein p53, is located on the short arm of chromosome 17 (17p). Patients with 17p deletion…”
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Novel-agent combination therapies in chronic lymphocytic leukemia: the law of relative contributions
Published in Haematologica (Roma) (01-09-2022)Get full text
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A clinical practice comparison of patients with chronic lymphocytic leukemia with and without deletion 17p receiving first-line treatment with ibrutinib
Published in Haematologica (Roma) (01-11-2022)“…Among patients with chronic lymphocytic leukemia (CLL) with deletion 17p (del[17p]), evidence from clinical trials for the effectiveness of single-agent…”
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All in the family: back-to-back kinase inhibitors for the treatment of chronic lymphocytic Leukemia
Published in Haematologica (Roma) (01-09-2021)Get full text
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The impact of early discontinuation/dose modification of venetoclax on outcomes in patients with relapsed/refractory chronic lymphocytic leukemia: post-hoc analyses from the phase III MURANO study
Published in Haematologica (Roma) (01-01-2022)“…Fixed-duration venetoclax plus rituximab (VenR) has a manageable safety profile and improves survival in patients with relapsed/refractory (R/R) chronic…”
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Utility of positron emission tomography-computed tomography in patients with chronic lymphocytic leukemia following B-cell receptor pathway inhibitor therapy
Published in Haematologica (Roma) (01-11-2019)“…The utility of positron emission tomography-computed tomography (PET-CT) in distinguishing Richter's transformation chronic lymphocytic leukemia (CLL)…”
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Acalabrutinib and Its Therapeutic Potential in the Treatment of Chronic Lymphocytic Leukemia: A Short Review on Emerging Data
Published in Cancer management and research (01-01-2020)“…Recently, the treatment landscape for chronic lymphocytic leukemia (CLL) has changed dramatically due to the development of drugs targeting proteins in the B…”
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A predictive approach in modeling and simulation of heat and mass transfer during microwave heating. Application to SFME of essential oil of Lavandin Super
Published in Chemical engineering science (22-01-2012)“…Solvent Free Microwave Extraction (SFME) is a new and faster process with higher energy efficiency used to extract essential oils. Nevertheless, so far no…”
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Real-World Evidence for Chronic Lymphocytic Leukemia in the Era of Targeted Therapies
Published in The cancer journal (Sudbury, Mass.) (01-11-2019)“…The landscape of chronic lymphocytic leukemia has transformed in the era of small molecule inhibitor targeted therapies. While randomized controlled trials…”
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COVID‐19 Vaccination Response and Its Practical Application in Patients With Chronic Lymphocytic Leukemia
Published in HemaSphere (01-01-2023)“…Patients with chronic lymphocyticleukemia (CLL) typically have innate/adaptive immune system dysregulation, thus the protective effect of coronavirus disease…”
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The potential of pirtobrutinib in multiple B-cell malignancies
Published in Therapeutic Advances in Hematology (2022)“…Bruton’s tyrosine kinase (BTK) is a critical downstream signaling element from the B-cell receptor (BCR) that has been effectively inhibited in B-cell cancers…”
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Zanubrutinib (BGB-3111), a Second-Generation Selective Covalent Inhibitor of Bruton's Tyrosine Kinase and Its Utility in Treating Chronic Lymphocytic Leukemia
Published in Drug design, development and therapy (01-01-2021)“…The understanding of the B cell receptor (BCR) pathway and its contribution to chronic lymphocytic leukemia (CLL) pathogenesis have led to the development of…”
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Addition of lenalidomide to rituximab, ifosfamide, carboplatin, etoposide (RICER) in first‐relapse/primary refractory diffuse large B‐cell lymphoma
Published in British journal of haematology (01-07-2014)“…Summary Relapsed/refractory diffuse large B‐cell lymphoma (DLBCL) is associated with a poor prognosis. Outcomes are particularly poor following…”
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Concrete block production from construction and demolition waste in Tanzania
Published in Resources, conservation and recycling (01-03-2013)“…► Construction and demolition waste was recycled into building materials in Tanzania. ► Eight samples of masonry rubble were recycled in to concrete blocks. ►…”
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PET/Computed Tomography in Chronic Lymphocytic Leukemia and Richter Transformation
Published in PET clinics (01-07-2019)“…Chronic lymphocytic leukemia (CLL) is the most common leukemia in the United States. In 1-10% of cases, it can undergo Richter's transformation (RT) to either…”
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Reduced‐dose fludarabine, cyclophosphamide, and rituximab (FCR‐Lite) plus lenalidomide, followed by lenalidomide consolidation/maintenance, in previously untreated chronic lymphocytic leukemia
Published in American journal of hematology (01-06-2015)“…Fludarabine, cyclophosphamide, and rituximab (FCR) remains the standard of care for fit chronic lymphocytic leukemia (CLL) patients requiring first therapy…”
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Multicenter Analysis of Advanced Stage Grade 3A Follicular Lymphoma Outcomes by Frontline Treatment Regimen
Published in Clinical lymphoma, myeloma and leukemia (01-02-2019)“…Grade 3A follicular lymphoma (FL) is a heterogenous disease with multiple frontline treatment regimens. We performed a multicenter retrospective analysis to…”
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