Search Results - "Matlock, Brittany K"

Combinatorial Transcriptional Profiling of Mouse and Human Enteric Neurons Identifies Shared and Disparate Subtypes In Situ by May-Zhang, Aaron A., Tycksen, Eric, Southard-Smith, Austin N., Deal, Karen K., Benthal, Joseph T., Buehler, Dennis P., Adam, Mike, Simmons, Alan J., Monaghan, James R., Matlock, Brittany K., Flaherty, David K., Potter, S. Steven, Lau, Ken S., Southard-Smith, E. Michelle

“…The enteric nervous system (ENS) coordinates essential intestinal functions through the concerted action of diverse enteric neurons (ENs). However, integrated…”
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WIN site inhibition disrupts a subset of WDR5 function by Siladi, Andrew J., Wang, Jing, Florian, Andrea C., Thomas, Lance R., Creighton, Joy H., Matlock, Brittany K., Flaherty, David K., Lorey, Shelly L., Howard, Gregory C., Fesik, Stephen W., Weissmiller, April M., Liu, Qi, Tansey, William P.

“…WDR5 nucleates the assembly of histone-modifying complexes and acts outside this context in a range of chromatin-centric processes. WDR5 is also a prominent…”
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Novel kidney dissociation protocol and image-based flow cytometry facilitate improved analysis of injured proximal tubules by Manolopoulou, Marika, Matlock, Brittany K, Nlandu-Khodo, Stellor, Simmons, Alan J, Lau, Ken S, Phillips-Mignemi, Melanie, Ivanova, Alla, Alford, Catherine E, Flaherty, David K, Gewin, Leslie S

“…Flow cytometry studies on injured kidney tubules are complicated by the low yield of nucleated single cells. Furthermore, cell-specific responses such as cell…”
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Multiparameter analysis of stimulated human peripheral blood mononuclear cells: A comparison of mass and fluorescence cytometry by Nicholas, Katherine J., Greenplate, Allison R., Flaherty, David K., Matlock, Brittany K., Juan, Juan San, Smith, Rita M., Irish, Jonathan M., Kalams, Spyros A.

“…Mass and fluorescence cytometry are quantitative single cell flow cytometry approaches that are powerful tools for characterizing diverse tissues and cellular…”
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Protocol for isolating specific C. elegans neuron types for bulk and single-cell RNA sequencing by Taylor, Seth R., McWhirter, Rebecca D., Matlock, Brittany K., Flaherty, David K., Miller, David M.

“…The C. elegans nervous system is compact and well described, ideal for identifying genetic programs that drive neuron-specific development, function, and…”
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The LRRC8 volume‐regulated anion channel inhibitor, DCPIB, inhibits mitochondrial respiration independently of the channel by Afzal, Aqeela, Figueroa, Eric E., Kharade, Sujay V., Bittman, Kevin, Matlock, Brittany K., Flaherty, David K., Denton, Jerod S.

“…There has been a resurgence of interest in the volume‐regulated anion channel (VRAC) since the recent cloning of the LRRC8A‐E gene family that encodes VRAC…”
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Neutrophil trafficking to the site of infection requires Cpt1a-dependent fatty acid β-oxidation by Pham, Ly, Komalavilas, Padmini, Eddie, Alex M., Thayer, Timothy E., Greenwood, Dalton L., Liu, Ken H., Weinberg, Jaclyn, Patterson, Andrew, Fessel, Joshua P., Boyd, Kelli L., Schafer, Jenny C., Kuck, Jamie L., Shaver, Aaron C., Flaherty, David K., Matlock, Brittany K., Wijers, Christiaan D. M., Serezani, C. Henrique, Jones, Dean P., Brittain, Evan L., Rathmell, Jeffrey C., Noto, Michael J.

“…Cellular metabolism influences immune cell function, with mitochondrial fatty acid β-oxidation and oxidative phosphorylation required for multiple immune cell…”
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Synergistic action of WDR5 and HDM2 inhibitors in SMARCB1-deficient cancer cells by Florian, Andrea C, Woodley, Chase M, Wang, Jing, Grieb, Brian C, Slota, Macey J, Guerrazzi, Kiana, Hsu, Chih-Yuan, Matlock, Brittany K, Flaherty, David K, Lorey, Shelly L, Fesik, Stephen W, Howard, Gregory C, Liu, Qi, Weissmiller, April M, Tansey, William P

“…Rhabdoid tumors (RT) are rare and deadly pediatric cancers driven by loss of , which encodes the SNF5 component of the SWI/SNF chromatin remodeler. Loss of is…”
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Cell-Cycle Control of Developmentally Regulated Transcription Factors Accounts for Heterogeneity in Human Pluripotent Cells by Singh, Amar M., Chappell, James, Trost, Robert, Lin, Li, Wang, Tao, Tang, Jie, Matlock, Brittany K., Weller, Kevin P., Wu, Hao, Zhao, Shaying, Jin, Peng, Dalton, Stephen

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Methotrexate Inhibits NF‐κB Activity Via Long Intergenic (Noncoding) RNA–p21 Induction by Spurlock, Charles F., Tossberg, John T., Matlock, Brittany K., Olsen, Nancy J., Aune, Thomas M.

“…Objective To determine interrelationships between the expression of long intergenic (noncoding) RNA–p21 (lincRNA‐p21), NF‐κB activity, and responses to…”
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A single-cell atlas of mouse lung development by Negretti, Nicholas M, Plosa, Erin J, Benjamin, John T, Schuler, Bryce A, Habermann, A Christian, Jetter, Christopher S, Gulleman, Peter, Bunn, Claire, Hackett, Alice N, Ransom, Meaghan, Taylor, Chase J, Nichols, David, Matlock, Brittany K, Guttentag, Susan H, Blackwell, Timothy S, Banovich, Nicholas E, Kropski, Jonathan A, Sucre, Jennifer M S

“…Lung organogenesis requires precise timing and coordination to effect spatial organization and function of the parenchymal cells. To provide a systematic…”
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Obesity induced by a high-fat diet is associated with increased immune cell entry into the central nervous system by Buckman, Laura B, Hasty, Alyssa H, Flaherty, David K, Buckman, Christopher T, Thompson, Misty M, Matlock, Brittany K, Weller, Kevin, Ellacott, Kate L.J

“…Highlight • High-fat diet induced obesity is associated with CNS recruitment of monocytes with the phenotype of activated microglia/macrophage…”
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WDR5 is a conserved regulator of protein synthesis gene expression by Bryan, Audra F, Wang, Jing, Howard, Gregory C, Guarnaccia, Alissa D, Woodley, Chase M, Aho, Erin R, Rellinger, Eric J, Matlock, Brittany K, Flaherty, David K, Lorey, Shelly L, Chung, Dai H, Fesik, Stephen W, Liu, Qi, Weissmiller, April M, Tansey, William P

“…Abstract WDR5 is a highly-conserved nuclear protein that performs multiple scaffolding functions in the context of chromatin. WDR5 is also a promising target…”
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Cell-type-specific and disease-associated expression quantitative trait loci in the human lung by Natri, Heini M., Del Azodi, Christina B., Peter, Lance, Taylor, Chase J., Chugh, Sagrika, Kendle, Robert, Chung, Mei-i, Flaherty, David K., Matlock, Brittany K., Calvi, Carla L., Blackwell, Timothy S., Ware, Lorraine B., Bacchetta, Matthew, Walia, Rajat, Shaver, Ciara M., Kropski, Jonathan A., McCarthy, Davis J., Banovich, Nicholas E.

“…Common genetic variants confer substantial risk for chronic lung diseases, including pulmonary fibrosis. Defining the genetic control of gene expression in a…”
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Multiple interactions of the oncoprotein transcription factor MYC with the SWI/SNF chromatin remodeler by Woodley, Chase M., Romer, Alexander S., Wang, Jing, Guarnaccia, Alissa D., Elion, David L., Maxwell, Jack N., Guerrazzi, Kiana, McCann, Tyler S., Popay, Tessa M., Matlock, Brittany K., Flaherty, David K., Lorey, Shelly L., Liu, Qi, Tansey, William P., Weissmiller, April M.

“…The SNF5 subunit of the SWI/SNF chromatin remodeling complex has been shown to act as a tumor suppressor through multiple mechanisms, including impairing the…”
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Author Correction: Cell-type-specific and disease-associated expression quantitative trait loci in the human lung by Natri, Heini M., Del Azodi, Christina B., Peter, Lance, Taylor, Chase J., Chugh, Sagrika, Kendle, Robert, Chung, Mei-i, Flaherty, David K., Matlock, Brittany K., Calvi, Carla L., Blackwell, Timothy S., Ware, Lorraine B., Bacchetta, Matthew, Walia, Rajat, Shaver, Ciara M., Kropski, Jonathan A., McCarthy, Davis J., Banovich, Nicholas E.

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Improved proliferation of antigen-specific cytolytic T lymphocytes using a multimodal nanovaccine by Li, Bo, Siuta, Michael, Bright, Vanessa, Koktysh, Dmitry, Matlock, Brittany K, Dumas, Megan E, Zhu, Meiying, Holt, Alex, Stec, Donald, Deng, Shenglou, Savage, Paul B, Joyce, Sebastian, Pham, Wellington

“…The present study investigated the immunoenhancing property of our newly designed nanovaccine, that is, its ability to induce antigen-specific immunity. This…”
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Cell-Cycle Control of Developmentally Regulated Transcription Factors Accounts for Heterogeneity in Human Pluripotent Cells by Singh, Amar M., Chappell, James, Trost, Robert, Lin, Li, Wang, Tao, Tang, Jie, Wu, Hao, Zhao, Shaying, Jin, Peng, Dalton, Stephen

“…Heterogeneity within pluripotent stem cell (PSC) populations is indicative of dynamic changes that occur when cells drift between different states. Although…”
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Methotrexate inhibits NF-κB activity via lincRNA-p21 induction by Spurlock, Charles F., Tossberg, John T., Matlock, Brittany K., Olsen, Nancy J., Aune, Thomas M.

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Methotrexate Inhibits NF-[kappa]B Activity Via Long Intergenic (Noncoding) RNA-p21 Induction by Spurlock, Charles F, Tossberg, John T, Matlock, Brittany K, Olsen, Nancy J, Aune, Thomas M

“…Objective To determine interrelationships between the expression of long intergenic (noncoding) RNA-p21 (lincRNA-p21), NF-[kappa]B activity, and responses to…”
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