Search Results - "Matkó, János"

Local apoptotic-like mechanisms underlie complement-mediated synaptic pruning by Györffy, Balázs A., Kun, Judit, Török, György, Bulyáki, Éva, Borhegyi, Zsolt, Gulyássy, Péter, Kis, Viktor, Szocsics, Péter, Micsonai, András, Matkó, János, Drahos, László, Juhász, Gábor, Kékesi, Katalin A., Kardos, József

“…C1q, a member of the immune complement cascade, is implicated in the selective pruning of synapses by microglial phagocytosis. C1q-mediated synapse elimination…”
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Improved characterization of EV preparations based on protein to lipid ratio and lipid properties by Osteikoetxea, Xabier, Balogh, Andrea, Szabó-Taylor, Katalin, Németh, Andrea, Szabó, Tamás Géza, Pálóczi, Krisztina, Sódar, Barbara, Kittel, Ágnes, György, Bence, Pállinger, Éva, Matkó, János, Buzás, Edit Irén

“…In recent years the study of extracellular vesicles has gathered much scientific and clinical interest. As the field is expanding, it is becoming clear that…”
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Molecular Relay Stations in Membrane Nanotubes: IRSp53 Involved in Actin-Based Force Generation by Madarász, Tamás, Brunner, Brigitta, Halász, Henriett, Telek, Elek, Matkó, János, Nyitrai, Miklós, Szabó-Meleg, Edina

“…Membrane nanotubes are cell protrusions that grow to tens of micrometres and functionally connect cells. Actin filaments are semi-flexible polymers, and their…”
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Revisiting the Coreceptor Function of Complement Receptor Type 2 (CR2, CD21); Coengagement With the B-Cell Receptor Inhibits the Activation, Proliferation, and Antibody Production of Human B Cells by Kovács, Kristóf G, Mácsik-Valent, Bernadett, Matkó, János, Bajtay, Zsuzsa, Erdei, Anna

“…The positive coreceptor function of complement receptor type 2 [CR2 (CD21)] on B cells is generally accepted, although its role in the enhancement of antibody…”
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Membrane nanotubes are ancient machinery for cell-to-cell communication and transport. Their interference with the immune system by Matkó, János, Tóth, Eszter Angéla

“…Nanotubular connections between mammalian cell types came into the focus only two decades ago, when "live cell super-resolution imaging" was introduced…”
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Stromal Cells Serve Drug Resistance for Multiple Myeloma via Mitochondrial Transfer: A Study on Primary Myeloma and Stromal Cells by Matula, Zsolt, Mikala, Gábor, Lukácsi, Szilvia, Matkó, János, Kovács, Tamás, Monostori, Éva, Uher, Ferenc, Vályi-Nagy, István

“…Recently, it has become evident that mitochondrial transfer (MT) plays a crucial role in the acquisition of cancer drug resistance in many hematologic…”
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Cooperation of Various Cytoskeletal Components Orchestrates Intercellular Spread of Mitochondria between B-Lymphoma Cells through Tunnelling Nanotubes by Halász, Henriett, Tárnai, Viktória, Matkó, János, Nyitrai, Miklós, Szabó-Meleg, Edina

“…Membrane nanotubes (NTs) are dynamic communication channels connecting spatially separated cells even over long distances and promoting the transport of…”
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Placental galectins regulate innate and adaptive immune responses in pregnancy by Oravecz, Orsolya, Romero, Roberto, Tóth, Eszter, Kapitány, Judit, Posta, Máté, Gallo, Dahiana M, Rossi, Simona W, Tarca, Adi L, Erez, Offer, Papp, Zoltán, Matkó, János, Than, Nándor Gábor, Balogh, Andrea

“…Galectins are master regulators of maternal immune responses and placentation in pregnancy. Galectin-13 (gal-13) and galectin-14 (gal-14) are expressed solely…”
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Proinflammatory activation pattern of human umbilical vein endothelial cells induced by IL‐1β, TNF‐α, and LPS by Makó, Veronika, Czúcz, Judit, Weiszhár, Zsóka, Herczenik, Eszter, Matkó, János, Prohászka, Zoltán, Cervenak, László

“…Endothelial cells play a critical role in inflammation by responding to several endogenous and exogenous proinflammatory stimuli. The three most studied…”
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Placental protein 13 (PP13/galectin-13) undergoes lipid raft-associated subcellular redistribution in the syncytiotrophoblast in preterm preeclampsia and HELLP syndrome by Balogh, Andrea, PhD, Pozsgay, Judit, MSc, Matkó, János, DSc, Dong, Zhong, MD, PhD, Kim, Chong Jai, MD, PhD, Várkonyi, Tibor, MD, Sammar, Marei, DSc, Rigó, János, MD, DSc, Meiri, Hamutal, PhD, Romero, Roberto, MD, Papp, Zoltán, MD, DSc, Than, Nándor Gábor, MD, PhD

“…Objective To investigate placental protein 13 (PP13) localization in relation to cytoskeleton and lipid rafts in preeclampsia and HELLP syndrome. Study Design…”
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Inflammatory signal induced IL-10 production of marginal zone B-cells depends on CREB by Barátki, Balázs L., Huber, Krisztina, Sármay, Gabriella, Matkó, János, Kövesdi, Dorottya

“…•The BCR, TLR9 and IFN-γ receptors induce IL-10 expression by MZ B-cells.•Activation of CREB is prolonged in MZ B-cells but not in FO B-cells.•Sustained…”
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B cell receptor-induced Ca2+ mobilization mediates F-actin rearrangements and is indispensable for adhesion and spreading of B lymphocytes by Maus, Máté, Medgyesi, David, Kiss, Endre, Schneider, Andrea E., Enyedi, Ágnes, Szilágyi, Nóra, Matkó, János, Sármay, Gabriella

“…A molecular mechanism for Ca2+‐regulated actin cytoskeleton redistribution during B cell spreading on antigentethered surfaces. B cells acquire membrane‐bound…”
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FcRn overexpression in transgenic mice results in augmented APC activity and robust immune response with increased diversity of induced antibodies by Végh, Attila, Farkas, Anita, Kövesdi, Dorottya, Papp, Krisztián, Cervenak, Judit, Schneider, Zita, Bender, Balázs, Hiripi, László, László, Glória, Prechl, József, Matkó, János, Kacskovics, Imre

“…Our previous studies have shown that overexpression of bovine FcRn (bFcRn) in transgenic (Tg) mice leads to an increase in the humoral immune response,…”
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Fluorescence activated cell sorting followed by small RNA sequencing reveals stable microRNA expression during cell cycle progression by Grolmusz, Vince Kornél, Tóth, Eszter Angéla, Baghy, Kornélia, Likó, István, Darvasi, Ottó, Kovalszky, Ilona, Matkó, János, Rácz, Károly, Patócs, Attila

“…Previously, drug-based synchronization procedures were used for characterizing the cell cycle dependent transcriptional program. However, these synchronization…”
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CD3ζ-chain expression of human T lymphocytes is regulated by TNF via Src-like adaptor protein-dependent proteasomal degradation by Érsek, Barbara, Molnár, Viktor, Balogh, Andrea, Matkó, János, Cope, Andrew P, Buzás, Edit I, Falus, András, Nagy, György

“…Decreased expression of the TCR ζ-chain has been reported in several autoimmune, inflammatory, and malignant diseases, suggesting that ζ-chain downregulation…”
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Estrogen augments the T cell-dependent but not the T-independent immune response by Ádori, Mónika, Kiss, Endre, Barad, Zsuzsanna, Barabás, Klaudia, Kiszely, Edda, Schneider, Andrea, Sziksz, Erna, Ábrahám, István M, Matkó, János, Sármay, Gabriella

“…Estrogen plays a critical regulatory role in the development and maintenance of immunity. Its role in the regulation of antibody synthesis in vivo is still not…”
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Acid sphingomyelinase mediated release of ceramide is essential to trigger the mitochondrial pathway of apoptosis by galectin-1 by Ion, Gabriela, Fajka-Boja, Roberta, Kovács, Ferenc, Szebeni, Gábor, Gombos, Imre, Czibula, Ágnes, Matkó, János, Monostori, Éva

“…The mechanism of apoptosis induced by human galectin-1, a mammalian β-galactoside-binding protein with a remarkable cytotoxic effect on activated peripheral T…”
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Some new faces of membrane microdomains: A complex confocal fluorescence, differential polarization, and FCS imaging study on live immune cells by Gombos, Imre, Steinbach, Gábor, Pomozi, István, Balogh, Andrea, Vámosi, György, Gansen, Alexander, László, Glória, Garab, Győző, Matkó, János

“…Lipid rafts are cholesterol- and glycosphingolipid-rich plasma membrane microdomains, which control signal transduction, cellular contacts, pathogen…”
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Cytometry of raft and caveola membrane microdomains: From flow and imaging techniques to high throughput screening assays by Kiss, Endre, Nagy, Péter, Balogh, Andrea, Szöllősi, János, Matkó, János

“…The evolutionarily developed microdomain structure of biological membranes has gained more and more attention in the past decade. The caveolin‐free “membrane…”
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Raft and cytoskeleton associations of an ABC transporter: P‐glycoprotein by Bacso, Zsolt, Nagy, Henrietta, Goda, Katalin, Bene, László, Fenyvesi, Ferenc, Matkó, János, Szabó, Gábor

“…Background A novel flow cytometric assay has been described in an accompanying report (Gombos et al., Methods The kinetics of the decrease in…”
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