Search Results - "Matias, Mariana Leticia"
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Silibinin Downregulates the NF-κB Pathway and NLRP1/NLRP3 Inflammasomes in Monocytes from Pregnant Women with Preeclampsia
Published in Molecules (Basel, Switzerland) (19-04-2019)“…Preeclampsia (PE) is a human pregnancy-specific syndrome with abnormal activation of cells from the innate immune system. The present study evaluated whether…”
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Endogenous and Uric Acid-Induced Activation of NLRP3 Inflammasome in Pregnant Women with Preeclampsia
Published in PloS one (08-06-2015)“…Preeclampsia (PE) is a specific syndrome of pregnancy, characterized by hypertension and proteinuria. This pathology is associated with hyperuricemia and…”
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Association between Adverse Maternal Clinical Outcomes and Imbalance of Cytokines and Angiogenic Factors in Preterm Preeclampsia
Published in Revista Brasileira de ginecologia e obstetrícia (01-09-2021)“…Preeclampsia (PE) is a pregnancy-specific syndrome characterized by abnormal levels of cytokines and angiogenic factors, playing a role in the disease…”
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Silibinin induces in vitro M2-like phenotype polarization in monocytes from preeclamptic women
Published in International immunopharmacology (01-12-2020)“…•Silibinin has immunomodulatory effect on the sterile inflammation of preeclampsia.•Silibinin treated-monocytes from preeclamptic women polarises to M2…”
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DAMPs are able to skew CD4+ T cell subsets and increase the inflammatory profile in pregnant women with preeclampsia
Published in Journal of reproductive immunology (01-02-2022)“…•Sterile inflammation is up-regulated by the presence of DAMPs in preeclampsia.•DAMPs stimulation can contribute to the activation of the adaptive immunity in…”
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Vitamin D modulates the transcription factors of T cell subsets to anti-inflammatory and regulatory profiles in preeclampsia
Published in International immunopharmacology (01-12-2021)“…[Display omitted] •Vitamin D downregulatesthe sterile inflammation in preeclampsia.•Pregnant women with preeclampsia have lower plasmatic levels of…”
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Progesterone and vitamin D downregulate the activation of the NLRP1/NLRP3 inflammasomes and TLR4-MyD88-NF-κB pathway in monocytes from pregnant women with preeclampsia
Published in Journal of reproductive immunology (01-04-2021)“…Graphical abstract showing the immunomodulatory effect of progesterone (PG) and vitamin D (VD) on the inflammatory state of monocytes from preeclamptic women…”
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Induction of systemic inflammation by hyaluronan and hsp70 in women with pre-eclampsia
Published in Cytokine (Philadelphia, Pa.) (01-05-2018)“…•DAMPs involvement in systemic inflammation of pre-eclampsia.•Hyaluronan stimulate inflammasome activation in monocytes from pre-eclamptic women.•Hsp70 induce…”
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Hydrogen peroxide-mediated oxidative stress induces inflammasome activation in term human placental explants
Published in Pregnancy hypertension (01-10-2018)“…•Oxidative stress activate inflammasome, with pro-inflammatory cytokine production.•Inflammasome activation could be a response to oxidative…”
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173. Vitamin D modulates the inflammatory response in T cell subsets from pregnant women with preeclampsia
Published in Pregnancy hypertension (01-10-2018)“…Preeclampsia (PE) is a specific pregnancy syndrome characterized by an imbalance between the inflammatory T cell (Th1 and Th17) and the anti-inflammatory (Th2…”
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171. Association between adverse maternal clinical outcomes and imbalance of cytokines and angiogenic factors in preterm preeclampsia
Published in Pregnancy hypertension (01-10-2018)“…Preeclampsia (PE) is a pregnancy specific syndrome, characterized by abnormal levels of cytokines and angiogenic factors, suggesting that immunological factors…”
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127. Haptoglobin deficiency in the inflammatory process of preeclampsia
Published in Pregnancy hypertension (01-10-2018)“…Preeclampsia is a specific pregnancy syndrome characterized by a systemic inflammatory response associated with the production of proinflammatory cytokines and…”
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172. Vitamin D decreases gene and protein expression of NLRP3 inflammasome in placental explants cultured with hydrogen peroxide from women with preeclampsia
Published in Pregnancy hypertension (01-10-2018)“…Pregnancies complicated by preeclampsia (PE) are associated with placental oxidative stress and related to the activation of NLRP3 inflammasome, an important…”
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P 14 Deficiency of regulatory profile in pregnant women with early-onset preeclampsia
Published in Pregnancy hypertension (01-07-2017)“…Preeclampsia (PE) is a pregnancy specific syndrome characterized by a systemic inflammatory response. An imbalance between Th17 and regulatory T cell detected…”
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P 11 Hydrogen peroxide-induced inflammation and decreased vitamin D receptor in placental explants
Published in Pregnancy hypertension (01-07-2017)“…Placental oxidative stress has been associated with the pathogenesis of preeclampsia (PE). The imbalance between pro- and anti-inflammatory cytokines in this…”
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P 13 Inflammasome downregulation by silibinin and vitamin D in monocytes from pregnant women with preeclampsia
Published in Pregnancy hypertension (01-07-2017)“…Preeclampsia (PE) is characterized by a state of abnormal activation of the innate immune system. This pathology is associated with activation of inflammasome,…”
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99 Endogenous activation of inflammatory profiles Th1 and Th17 in lymphocytes from pregnant women with preeclampsia : Immune and inflammatory mechanisms
Published in Pregnancy hypertension (01-07-2016)“…Preeclampsia (PE) is a systemic disease characterized by multiple alterations in the maternal organism and clinically identified by hypertension and…”
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69 Oxidative stress induces inflammatory response in placental explants: Immune and inflammatory mechanisms
Published in Pregnancy hypertension (01-07-2016)“…Oxidative stress arises from imbalance between generation of reactive oxygen species and anti-oxidant capacity of specific tissues. This alteration has been…”
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26 Inflammasome activation in placenta from pregnant women with preeclampsia: Immune and inflammatory mechanisms
Published in Pregnancy hypertension (01-07-2016)“…Preeclampsia (PE) is a pregnancy disorder characterized by an imbalance between pro- and anti-inflammatory cytokines associated with high plasma levels of uric…”
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69 MSU and HA stimuli enhance autophagy in monocytes from pregnant women with preeclampsia: Immune and inflammatory mechanisms
Published in Pregnancy hypertension (01-07-2016)“…Preeclampsia (PE) is a clinical complication of pregnancy associated with elevated serum levels of inflammatory cytokines, leukocyte activation and oxidative…”
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