Search Results - "Mathur, Premendu P"

Targeting Kinase Interaction Networks: A New Paradigm in PPI Based Design of Kinase Inhibitors by Jenardhanan, Pranitha, Panneerselvam, Manivel, Mathur, Premendu P

“…Kinases are key modulators in regulating diverse range of cellular activities and are an essential part of the protein-protein interactome. Understanding the…”
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Sertoli cell as a model in male reproductive toxicology: Advantages and disadvantages by Reis, Mariana M. S., Moreira, Ana C., Sousa, Mário, Mathur, Premendu P., Oliveira, Pedro F., Alves, Marco G.

“…Pressure towards population aging in the demographic pyramid is not only due to sociological/personal choices but also due to subfertility or infertility…”
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Cigarette smoke and chewing tobacco alter expression of different sets of miRNAs in oral keratinocytes by Bhat, Mohd Younis, Advani, Jayshree, Rajagopalan, Pavithra, Patel, Krishna, Nanjappa, Vishalakshi, Solanki, Hitendra S., Patil, Arun H., Bhat, Firdous A., Mathur, Premendu P., Nair, Bipin, Prasad, T. S. Keshava, Califano, Joseph A., Sidransky, David, Gowda, Harsha, Chatterjee, Aditi

“…Carcinogenic effect of tobacco in oral cancer is through chewing and/or smoking. Significant differences exist in development of oral cancer between tobacco…”
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Potential biological role of poly (ADP-ribose) polymerase (PARP) in male gametes by Agarwal, Ashok, Mahfouz, Reda Z, Sharma, Rakesh K, Sarkar, Oli, Mangrola, Devna, Mathur, Premendu P

“…Maintaining the integrity of sperm DNA is vital to reproduction and male fertility. Sperm contain a number of molecules and pathways for the repair of base…”
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Editorial: Systemic Regulation of Organ Homeostasis and Implications of Hormones and Immunity by Anbazhagan, Rajakumar, Kavarthapu, Raghuveer, Mathur, Premendu P, Kostic, Tatjana S, Prakash, Hridayesh

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Interleukin 1 Alpha (IL1A) Is a Novel Regulator of the Blood-Testis Barrier in the Rat by Sarkar, Oli, Mathur, Premendu P, Cheng, C. Yan, Mruk, Dolores D

“…Throughout spermatogenesis, leptotene spermatocytes must traverse the blood-testis barrier (BTB) at stages VIII-XI to gain entry into the adluminal compartment…”
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Long-Term Cigarette Smoke Exposure and Changes in MiRNA Expression and Proteome in Non-Small-Cell Lung Cancer by Advani, Jayshree, Subbannayya, Yashwanth, Patel, Krishna, Khan, Aafaque Ahmad, Patil, Arun H, Jain, Ankit P, Solanki, Hitendra S, Radhakrishnan, Aneesha, Pinto, Sneha M, Sahasrabuddhe, Nandini A, Thomas, Joji K, Mathur, Premendu P, Nair, Bipin G, Chang, Xiaofei, Prasad, T S Keshava, Sidransky, David, Gowda, Harsha, Chatterjee, Aditi

“…Chronic exposure to cigarette smoke markedly increases the risk for lung cancer. Regulation of gene expression at the post-transcriptional level by miRNAs…”
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PepBind： A Comprehensive Database and Computational Tool for Analysis of Protein-peptide Interactions by Das, Arindam Atanu, Sharma, Om Prakash, Kumar, Muthuvel Suresh, Krishna, Ramadas, Mathur, Premendu P.

“…Protein-peptide interactions, where one partner is a globular protein （domain） and the other is a flexible linear peptide, are key components of cellular…”
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Chronic Exposure to Chewing Tobacco Induces Metabolic Reprogramming and Cancer Stem Cell-Like Properties in Esophageal Epithelial Cells by Datta, Keshava K, Patil, Shankargouda, Patel, Krishna, Babu, Niraj, Raja, Remya, Nanjappa, Vishalakshi, Mangalaparthi, Kiran Kumar, Dhaka, Bharti, Rajagopalan, Pavithra, Deolankar, Sayali Chandrashekhar, Kannan, Ramakrishnan, Kumar, Prashant, Prasad, T S Keshava, Mathur, Premendu P, Kumari, Anjali, Manoharan, Malini, Coral, Karunakaran, Murugan, Saktivel, Sidransky, David, Gupta, Ravi, Gupta, Rohit, Khanna-Gupta, Arati, Chatterjee, Aditi, Gowda, Harsha

“…Tobacco in its smoke and smokeless form are major risk factors for esophageal squamous cell carcinoma (ESCC). However, molecular alterations associated with…”
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Effect of environmental contaminants on spermatogenesis by Jenardhanan, Pranitha, Panneerselvam, Manivel, Mathur, Premendu P

“…Indiscriminate use of synthetic chemical compounds and the unregulated presence of heavy metals threatens the integral reproducibility of mankind and other…”
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Development of anti-HIV activity models of lysine sulfonamide analogs: a QSAR perspective by Muthukumaran, Rajagopalan, Sangeetha, Balasubramanian, Amutha, Ramaswamy, Mathur, Premendu P

“…Lysine sulfonamide and its structural analogs, a class of Human Immunodeficiency Virus protease inhibitors has gained importance in recent years due to its…”
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Analysis of CYP3A4-HIV-1 protease drugs interactions by computational methods for Highly Active Antiretroviral Therapy in HIV/AIDS by Jayakanthan, Mannu, Chandrasekar, Sanniyasi, Muthukumaran, Jayaraman, Mathur, Premendu P.

“…HIV infected patients often take at least three anti-HIV drugs together in Highly Active Antiretroviral Therapy (HAART) and/or Ritonavir-Boosted Protease…”
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Computational Methods Involved in Evaluating the Toxicity of the Reproductive Toxicants in Sertoli Cell by Jenardhanan, Pranitha, Panneerselvam, Manivel, Mathur, Premendu P

“…The Sertoli cell, the somatic component of seminiferous tubule, provides nutritional support and immunological protection and supports overall growth and…”
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Plasma Proteome Database as a resource for proteomics research: 2014 update by Nanjappa, Vishalakshi, Thomas, Joji Kurian, Marimuthu, Arivusudar, Muthusamy, Babylakshmi, Radhakrishnan, Aneesha, Sharma, Rakesh, Ahmad Khan, Aafaque, Balakrishnan, Lavanya, Sahasrabuddhe, Nandini A, Kumar, Satwant, Jhaveri, Binit Nitinbhai, Sheth, Kaushal Vinaykumar, Kumar Khatana, Ramesh, Shaw, Patrick G, Srikanth, Srinivas Manda, Mathur, Premendu P, Shankar, Subramanian, Nagaraja, Dindagur, Christopher, Rita, Mathivanan, Suresh, Raju, Rajesh, Sirdeshmukh, Ravi, Chatterjee, Aditi, Simpson, Richard J, Harsha, H C, Pandey, Akhilesh, Prasad, T S Keshava

“…Plasma Proteome Database (PPD; http://www.plasmaproteomedatabase.org/) was initially described in the year 2005 as a part of Human Proteome Organization's…”
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The structural analysis of MARK4 and the exploration of specific inhibitors for the MARK family: a computational approach to obstruct the role of MARK4 in prostate cancer progression by Jenardhanan, Pranitha, Mannu, Jayakanthan, Mathur, Premendu P

“…Prostate cancer, the second most common form of cancer in adult males is generally treated using hormone therapy but the emergence of hormone refractory…”
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Influence of the Genetic Polymorphisms in the 5' Flanking and Exonic Regions of CYP2C19 on Proguanil Oxidation by Satyanarayana, Chakradhara Rao Uppugunduri, Devendran, Anichavezhi, Jayaraman, Muthukumaran, Mannu, Jayakanthan, Mathur, Premendu P, Gopal, Shewade Deepak, Rajagopal, Krishnamoorthy, Chandrasekaran, Adithan

“…「Summary」CYP2C19 is a polymorphic enzyme which metabolizes several clinically important drugs including proguanil. Variation in the 5' regulatory region may…”
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Integrated multi-omics analysis reveals potential mechanisms of acquired resistance to erlotinib in head and neck cancer cells by Jain, Ankit P., Patel, Krishna, Pinto, Sneha, Nanjappa, Vishalakshi, Radhakrishnan, Aneesha, Kumari, Anjali, Manoharan, Malini, Karunakaran, Coral, Murugan, Saktivel, Prasad, T.S. Keshava, Mathur, Premendu P., Nair, Bipin, Gupta, Ravi, Gupta, Rohit, Khanna-Gupta, Arati, Sidransky, David, Chatterjee, Aditi, Gowda, Harsha

“…Abstract only…”
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Molecular alterations associated with chronic exposure to cigarette smoke and chewing tobacco in normal oral keratinocytes by Rajagopalan, Pavithra, Jain, Ankit P., Patel, Krishna, Nanjappa, Vishalakshi, Mangalparthi, Kiran K., Kumari, Anjali, Manoharan, Malini, Karunakaran, Coral, Murugan, Saktivel, Nair, Bipin, Prasad, T.S. Keshava, Mathur, Premendu P., Gupta, Ravi, Gupta, Rohit, Khanna-Gupta, Arati, Sidransky, David, Gowda, Harsha, Chatterjee, Aditi

“…Abstract only…”
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Use of Molecular Modeling to Study Spermatogenesis: An Overview Using Proteins in Sertoli Cells by Jenardhanan, Pranitha, Panneerselvam, Manivel, Mathur, Premendu P

“…Computational structure prediction and analysis helps in understanding the structure and function of varied proteins, which otherwise becomes implausible to…”
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Interaction of oligomeric breast cancer resistant protein (BCRP) with adjudin: a male contraceptive with anti-cancer activity by Cheng, Yan Ho, Jenardhanan, Pranitha, Mathur, Premendu P, Qian, Xiaojing, Xia, Weiliang, Silvestrini, Bruno, Cheng, Chuen Yan

“…Breast cancer resistant protein (BCRP, ABCG2) is an ATP-binding cassette (ABC) transporter, which together with two other ABC efflux drug pumps, namely…”
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