Search Results - "Mathis, Keisa W."

Preventing Autoimmunity Protects Against the Development of Hypertension and Renal Injury by Mathis, Keisa W, Wallace, Kedra, Flynn, Elizabeth R, Maric-Bilkan, Christine, LaMarca, Babbette, Ryan, Michael J

“…Several studies suggest a link between autoimmunity and essential hypertension in humans. However, whether autoimmunity can drive the development of…”
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MicroRNA-21 ablation exacerbates aldosterone-mediated cardiac injury, remodeling, and dysfunction by Syed, Maryam, Ball, Jana P, Mathis, Keisa W, Hall, Michael E, Ryan, Michael J, Rothenberg, Marc E, Yanes Cardozo, Licy L, Romero, Damian G

“…Primary aldosteronism is characterized by excess aldosterone secretion by the adrenal gland independent of the renin-angiotensin system and accounts for ~10%…”
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Should Renal Inflammation Be Targeted While Treating Hypertension? by Chaudhari, Sarika, Pham, Grace S, Brooks, Calvin D, Dinh, Viet Q, Young-Stubbs, Cassandra M, Shimoura, Caroline G, Mathis, Keisa W

“…Despite extensive research and a plethora of therapeutic options, hypertension continues to be a global burden. Understanding of the pathological roles of…”
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Editorial: Renal injury and the brain by Shimoura, Caroline G, Wallace, Kedra, Mathis, Keisa W

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Sex and strain differences in renal hemodynamics in mice by Tao, Yu, Young‐Stubbs, Cassandra, Yazdizadeh Shotorbani, Parisa, Su, Dong‐Ming, Mathis, Keisa W., Ma, Rong

“…The present study was to examine sex and strain differences in glomerular filtration rate (GFR) and renal blood flow (RBF) in C57BL6, 129/Sv, and C57BLKS/J…”
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Lipopolysaccharide Challenge Reveals Hypothalamic-Pituitary-Adrenal Axis Dysfunction in Murine Systemic Lupus Erythematosus by Pham, Grace S, Mathis, Keisa W

“…Crosstalk between the brain and innate immune system may be dysregulated in systemic lupus erythematosus (SLE), a chronic autoimmune disease that presents with…”
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Systemic Administration of α7-Nicotinic Acetylcholine Receptor Ligands Does Not Improve Renal Injury or Behavior in Mice With Advanced Systemic Lupus Erythematosus by Morales, Jessica Y, Young-Stubbs, Cassandra M, Shimoura, Caroline G, Kem, William R, Uteshev, Victor V, Mathis, Keisa W

“…There is a critical need for safe treatment options to control inflammation in patients with systemic lupus erythematosus (SLE) since the inflammation…”
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Store-operated Ca2+ channel signaling: Novel mechanism for podocyte injury in kidney disease by Tao, Yu, Mallet, Robert T, Mathis, Keisa W, Ma, Rong

“…Studies over the last decade have markedly broadened our understanding of store-operated Ca2+ channels (SOCs) and their roles in kidney diseases and podocyte…”
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Alcohol Binge Before Trauma/Hemorrhage Impairs Integrity of Host Defense Mechanisms During Recovery by Greiffenstein, Patrick, Mathis, Keisa W., Stouwe, Curtis Vande, Molina, Patricia E.

“…Background: Alcohol abuse, both chronic and acute, is a known modulator of immune function and is associated with increased incidence of traumatic injury…”
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Complementing T Regulatory Cells to Combat Hypertension by Mathis, Keisa W

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An impaired neuroimmune pathway promotes the development of hypertension in systemic lupus erythematosus by Mathis, Keisa W

“…Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disorder that affects nearly 2 million people in the United States. The majority of SLE…”
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Central Activation of the Cholinergic Anti‐Inflammatory Pathway Improves Outcome in a Murine Model of Systemic Lupus Erythematosus by Mathis, Keisa W., Shimoura, Caroline G., Stubbs, Cassandra, Brooks, Calvin

“…The cholinergic anti‐inflammatory pathway is an endogenous vagus‐to‐spleen mechanism that regulates the immune system and when activated, results in decreases…”
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Pharmacological potentiation of the efferent vagus nerve attenuates blood pressure and renal injury in a murine model of systemic lupus erythematosus by Pham, Grace S, Wang, Lei A, Mathis, Keisa W

“…Recent evidence suggests hypertension may be secondary to chronic inflammation that results from hypoactive neuro-immune regulatory mechanisms. To further…”
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When Memory Does Not Serve You Well by Shimoura, Caroline G., Mathis, Keisa W.

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Neogenin pathway positively regulates fibronectin production by glomerular mesangial cells by Chaudhari, Sarika, Yazdizadeh Shotorbani, Parisa, Tao, Yu, Kasetti, Ramesh, Zode, Gulab, Mathis, Keisa W, Ma, Rong

“…Neogenin, a transmembrane receptor, was recently found in kidney cells and immune cells. However, the function of neogenin signaling in kidney is not clear…”
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Renal TLR-7/TNF-α pathway as a potential female-specific mechanism in the pathogenesis of autoimmune-induced hypertension by Chaudhari, Sarika, D'Souza, Bradley M, Morales, Jessica Y, Young-Stubbs, Cassandra M, Shimoura, Caroline G, Ma, Rong, Mathis, Keisa W

“…Hypertension is prevalent in patients with systemic lupus erythematosus (SLE). The goal of the current study is to track the pathogenesis of hypertension and…”
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Targeted stimulation of the vagus nerve reduces renal injury in female mice with systemic lupus erythematosus by Shimoura, Caroline Gusson, Stubbs, Cassandra Y, Chaudhari, Sarika, Dinh, Viet Q, Mathis, Keisa W

“…Pharmacological stimulation of the vagus nerve has been shown to suppress inflammation and reduce blood pressure in a murine model of systemic lupus…”
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Supporting and promoting Black physiologists: how can the APS help? by Robinson, Austin T, Jenkins, Nathaniel D M, Sanchez, Sofia O, Haack, Karla K V, Lee, Dexter L, Mathis, Keisa W, Warrington, Junie P

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Renal TLR7 expression is associated with renal injury in female mouse model of systemic lupus erythematosus by Chaudhari, Sarika, D'Souza, Bradley M., Morales, Jessica Y., Lima, Caroline, Young‐Stubbs, Cassandra M., Ma, Rong, Mathis, Keisa W.

“…Background Systemic lupus erythematosus (SLE) is an autoimmune disorder associated with exaggerated immune activation, autoantibody production, and immune…”
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Anti-CD3 antibody therapy attenuates the progression of hypertension in female mice with systemic lupus erythematosus by Mathis, Keisa W., Taylor, Erin B., Ryan, Michael J.

“…[Display omitted] Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disorder with prevalent hypertension that significantly contributes…”
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