Search Results - "Mathieu, Patricia A"

Nonesterified cholesterol content of lysosomes modulates susceptibility to oxidant-induced permeabilization by Reiners, John J., Kleinman, Miriam, Kessel, David, Mathieu, Patricia A., Caruso, Joseph A.

“…Reactive oxygen species (ROS) can induce lysosomal membrane permeabilization (LMP). Photoirradiation of murine hepatoma 1c1c7 cultures preloaded with the…”
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Naturally occurring autoimmune disease in (NZB X NZW) F1 mice is correlated with suppression of MZ B cell development due to aberrant B Cell Receptor (BCR) signaling, which is exacerbated by exposure to inorganic mercury by Gill, Randall F, Mathieu, Patricia A, Lash, Lawrence H, Rosenspire, Allen J

“…Autoimmune diseases are multifactorial and include environmental as well as genetic drivers. Although much progress has been made in understanding the nature…”
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Sphingomyelins suppress the targeted disruption of lysosomes/endosomes by the photosensitizer NPe6 during photodynamic therapy by Caruso, Joseph A, Mathieu, Patricia A, Reiners, Jr, John J

“…Recent studies have described a biochemical pathway whereby lysosome disruption and the released proteases initiate the intrinsic apoptotic pathway…”
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The chemotherapeutic agents XK469 (2-{4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid) and SH80 (2-{4-[(7-bromo-2-quinolinyl)oxy]phenoxy}propionic acid) inhibit cytokinesis and promote polyploidy and induce senescence by Reiners, Jr, John J, Kleinman, Miriam, Joiakim, Aby, Mathieu, Patricia A

“…The therapeutic usefulness of the quinoxaline derivatives XK469 (2-{4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid) and SH80…”
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Oligodeoxynucleotide IMT504: Effects on Central Nervous System Repair Following Demyelination by Mathieu, Patricia A., Sampertegui, Yim Rodriguez, Elias, Fernanda, Silva, Alexis Silva, de Luján Calcagno, María, López, Ricardo, Adamo, Ana M.

“…Multiple sclerosis (MS) is an immune-mediated central nervous system (CNS) disease characterized by demyelination resulting from oligodendrocyte loss and…”
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Differential susceptibilities of murine hepatoma 1c1c7 and Tao cells to the lysosomal photosensitizer NPe6: influence of aryl hydrocarbon receptor on lysosomal fragility and protease contents by Caruso, Joseph A, Mathieu, Patricia A, Joiakim, Aby, Leeson, Brendan, Kessel, David, Sloane, Bonnie F, Reiners, Jr, John J

“…Irradiation of murine hepatoma 1c1c7 cultures presensitized with N-aspartyl chlorin e6 (NPe6) caused lysosomal disruption and apoptosis. Tao cells, a variant…”
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Superinduction of CYP1A1 in MCF10A cultures by cycloheximide, anisomycin, and puromycin: a process independent of effects on protein translation and unrelated to suppression of aryl hydrocarbon receptor proteolysis by the proteasome by Joiakim, Aby, Mathieu, Patricia A, Elliott, Althea A, Reiners, Jr, John J

“…Exposure of the human breast epithelial cell line MCF10A to > or = 1 microg/ml cycloheximide (CHX)-induced accumulations of CYP1A1 mRNA 6-fold greater than…”
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THE JUN N-TERMINAL KINASE INHIBITOR SP600125 IS A LIGAND AND ANTAGONIST OF THE ARYL HYDROCARBON RECEPTOR by JOIAKIM, Aby, MATHIEU, Patricia A, PALERMO, Christine, GASIEWICZ, Thomas A, REINERS, John J

“…Exposure of the immortalized human breast epithelial cell line MCF10A to the Jun N-terminal kinase (JNK) inhibitor anthra[1,9-cd]pyrazol-6(2 H )-one (SP600125)…”
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Demyelination-remyelination in the Central Nervous System: Ligand-dependent Participation of the Notch Signaling Pathway by Mathieu, Patricia A, Almeira Gubiani, María F, Rodríguez, Débora, Gómez Pinto, Laura I, Calcagno, María de Luján, Adamo, Ana M

“…Multiple sclerosis (MS) is an immune-mediated central nervous system disease mostly affecting young people. Multiple sclerosis and other neurodegenerative and…”
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TGF‐β pro‐oligodendrogenic effects on adult SVZ progenitor cultures and its interaction with the Notch signaling pathway by Gómez Pinto, Laura I., Rodríguez, Debora, Adamo, Ana M., Mathieu, Patricia A.

“…Adult neural progenitor cells (NPCs) are capable of differentiating into neurons, astrocytes, and oligodendrocytes throughout life. Notch and transforming…”
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Synergistic Suppression of NF1 Malignant Peripheral Nerve Sheath Tumor Cell Growth in Culture and Orthotopic Xenografts by Combinational Treatment with Statin and Prodrug Farnesyltransferase Inhibitor PAMAM G4 Dendrimers by Reiners, Jr, John J, Mathieu, Patricia A, Gargano, Mary, George, Irene, Shen, Yimin, Callaghan, John F, Borch, Richard F, Mattingly, Raymond R

“…Neurofibromatosis type 1 (NF1) is a disorder in which RAS is constitutively activated due to the loss of the Ras-GTPase-activating activity of neurofibromin…”
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Epidermal Growth Factor Receptor Kinase Inhibitors Synergize with TCDD to Induce CYP1A1/1A2 in Human Breast Epithelial MCF10A Cells by Joiakim, Aby, Mathieu, Patricia A, Shelp, Catherine, Boerner, Julie, Reiners, Jr, John J

“…CYP1A1 and CYP1A2 are transcriptionally activated in the human normal breast epithelial cell line MCF10A following exposure to…”
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p -Anilinoaniline Enhancement of Dioxin-Induced CYP1A1 Transcription and Aryl Hydrocarbon Receptor Occupancy of CYP1A1 Promoter: Role of the Cell Cycle by Elliott, Althea, Joiakim, Aby, Mathieu, Patricia A, Duniec-Dmuchowski, Zofia, Kocarek, Thomas A, Reiners, Jr, John J

“…The aryl hydrocarbon receptor (AhR) is targeted by ubiquitination for degradation by the proteasome shortly after its activation by…”
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Aryl Hydrocarbon Receptor Modulation of Tumor Necrosis Factor-α-induced Apoptosis and Lysosomal Disruption in a Hepatoma Model That Is Caspase-8-independent by Caruso, Joseph A., Mathieu, Patricia A., Joiakim, Aby, Zhang, Hong, Reiners, John J.

“…Recent studies suggest that the aryl hydrocarbon receptor (AhR) modulates susceptibilities to some pro-apoptotic agents. AhR-containing murine hepatoma 1c1c7…”
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The peptide specificities of the autoantibodies elicited by mouse hepatitis virus A59 by Duhalde-Vega, Maite, Loureiro, María E., Mathieu, Patricia A., Retegui, Lilia A.

“…Synthetic decapeptides ( N = 206) covering the entire sequence of mouse liver fumarylacetoacetate hydrolase (FAH) were used to analyze the specificities of the…”
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Sequence similarity and structural homologies are involved in the autoimmune response elicited by mouse hepatitis virus A59 by Mathieu, Patricia A., Gómez, Karina A., Coutelier, Jean-Paul, Retegui, Lilia A.

“…The features of autoantibodies (autoAb) to liver fumarylacetoacetate hydrolase (FAH) elicited in mice infected with mouse hepatitis virus (MHV) were studied by…”
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Identification of two liver proteins recognized by autoantibodies elicited in mice infected with mouse hepatitis virus A59 by Mathieu, Patricia A., Gómez, Karina A., Coutelier, Jean‐Paul, Retegui, Lilia A.

“…Western blot experiments showed that sera from mice infected with the mouse hepatitis virus strain A59 (MHV‐A59) contained autoantibodies (autoAb) that bound…”
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TGF-[beta] pro-oligodendrogenic effects on adult SVZ progenitor cultures and its interaction with the Notch signaling pathway by Gomez Pinto, Laura I, Rodriguez, Debora, Adamo, Ana M, Mathieu, Patricia A

“…Adult neural progenitor cells (NPCs) are capable of differentiating into neurons, astrocytes, and oligodendrocytes throughout life. Notch and transforming…”
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Detection of mouse hepatitis virus infection by assay of anti-liver autoantibodies by Mathieu, Patricia A, Gómez, Karina A, Coutelier, Jean-Paul, Retegui, Lilia A

“…The observation that mice infected with mouse hepatitis virus (MHV) develop autoantibodies directed mainly to liver fumarylacetoacetate hydrolase (FAH) enabled…”
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Non-esterified Cholesterol Content of Lysosomes Modulates Susceptibility to Oxidant-induced Permeabilization by Reiners, John J., Kleinman, Miriam, Kessel, David, Mathieu, Patricia A., Caruso, Joseph A.

“…Reactive oxygen species (ROS) can induce lysosomal membrane permeabilization (LMP). Photoirradiation of murine hepatoma 1c1c7 cultures preloaded with the…”
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