Search Results - "Mathias, Lucas Solla"
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Systemic arterial hypertension leads to decreased semen quality and alterations in the testicular microcirculation in rats
Published in Scientific reports (30-07-2019)“…Arterial hypertension is a cardiovascular disease that leads to important systemic alterations and drastically impairs normal organ function over time…”
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Effects of Triiodothyronine on Human Osteoblast-Like Cells: Novel Insights From a Global Transcriptome Analysis
Published in Frontiers in cell and developmental biology (17-06-2022)“…Background: Thyroid hormones play a significant role in bone development and maintenance, with triiodothyronine (T3) particularly being an important modulator…”
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Disruptive Effect of Organotin on Thyroid Gland Function Might Contribute to Hypothyroidism
Published in International journal of endocrinology (01-01-2019)“…A considerable increase in endocrine abnormalities has been reported over the last few decades worldwide. A growing exposure to endocrine-disrupting chemicals…”
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Irisin modulates genes associated with severe coronavirus disease (COVID-19) outcome in human subcutaneous adipocytes cell culture
Published in Molecular and cellular endocrinology (15-09-2020)“…Obesity patients are more susceptible to develop COVID-19 severe outcome due to the role of angiotensin-converting enzyme 2 (ACE2) in the viral infection. ACE2…”
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RNA-seq reveals that anti-obesity irisin and triiodothyronine (T3) hormones differentially affect the purinergic signaling transcriptomics in differentiated human adipocytes
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01-04-2023)“…The anti-obesity thyroid hormone, triiodothyronine (T3), and irisin, an exercise- and/or cold-induced myokine, stimulate thermogenesis and energy consumption…”
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Pitfalls and challenges of the purinergic signaling cascade in obesity
Published in Biochemical pharmacology (01-12-2020)“…[Display omitted] Obesity is a worldwide health problem which have reached pandemic proportions, now also including low and middle-income countries. Excessive…”
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The roles of triiodothyronine and irisin in improving the lipid profile and directing the browning of human adipose subcutaneous cells
Published in Molecular and cellular endocrinology (15-04-2020)“…Triiodothyronine (T3) and irisin (I) can modulate metabolic status, increase heat production, and promote differentiation of white adipose tissue (WAT) into…”
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The importance of estrogen for bone protection in experimental hyperthyroidism in human osteoblasts
Published in Life sciences (1973) (15-08-2019)“…Triiodothyronine (T3) and estrogen (E2) play important roles in the bone remodeling process and signaling of receptor activator of the nuclear factor-kappa β…”
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Adiponectin and Serine/Threonine Kinase Akt Modulation by Triiodothyronine and/or LY294002 in 3T3‐L1 Adipocytes
Published in Lipids (01-02-2019)“…Adipose tissue (AT), an endocrine organ that modulates several physiological functions by synthesizing and releasing adipokines such as adiponectin, is a…”
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10
Triiodothyronine activated extranuclear pathways upregulate adiponectin and leptin in murine adipocytes
Published in Molecular and cellular endocrinology (01-03-2020)“…Adiponectin and leptin, important for metabolic regulation, are synthesized and secreted by adipose tissue and are influenced by triiodothyronine (T3) that…”
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