Search Results - "Mathew, M.K"
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Mechanism of aggregation and membrane interactions of mammalian prion protein
Published in Biochimica et biophysica acta. Biomembranes (01-09-2018)“…The cellular prion protein (PrPC), which is present ubiquitously in all mammalian neurons, is normally found to be linked to the cell membrane through a…”
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Functional characterization of a transition metal ion transporter, OsZIP6 from rice (Oryza sativa L.)
Published in Plant physiology and biochemistry (01-12-2015)“…Micronutrients are important for the growth and development of plants, which deploy families of transporters for their uptake and distribution. We have…”
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Salt-Induced Remodeling of Spatially Restricted Clathrin-Independent Endocytic Pathways in Arabidopsis Root
Published in The Plant cell (01-04-2015)“…Endocytosis is a ubiquitous cellular process that is characterized well in animal cells in culture but poorly across intact, functioning tissue. Here, we…”
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Development of the Structural Core and of Conformational Heterogeneity during the Conversion of Oligomers of the Mouse Prion Protein to Worm-like Amyloid Fibrils
Published in Journal of molecular biology (19-10-2012)“…Understanding how structure develops during the course of amyloid fibril formation by the prion protein is important for understanding prion diseases…”
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Functional Properties of the Drosophila melanogaster Inositol 1,4,5-Trisphosphate Receptor Mutants
Published in Biophysical journal (01-06-2004)“…The inositol (1,4,5)-trisphosphate receptor (InsP 3R) is an intracellular calcium (Ca 2+) release channel that plays a crucial role in cell signaling. In…”
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Fluid flow modulates electrical activity in cardiac hERG potassium channels
Published in The Journal of biological chemistry (23-03-2018)“…Fluid movement within the heart generates substantial shear forces, but the effect of this mechanical stress on the electrical activity of the human heart has…”
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Retraction Notice to: The Pathogenic A116V Mutation Enhances Ion-Selective Channel Formation by Prion Protein in Membranes
Published in Biophysical journal (07-12-2021)Get full text
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The Ca 2+ Channel CNGC19 Regulates Arabidopsis Defense Against Spodoptera Herbivory
Published in The Plant cell (01-07-2019)“…Cellular calcium elevation is an important signal used by plants for recognition and signaling of environmental stress. Perception of the generalist insect, ,…”
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Haem homeostasis is regulated by the conserved and concerted functions of HRG-1 proteins
Published in Nature (19-06-2008)“…Haems are metalloporphyrins that serve as prosthetic groups for various biological processes including respiration, gas sensing, xenobiotic detoxification,…”
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The Ca2+ Channel CNGC19 Regulates Arabidopsis Defense Against Spodoptera Herbivory
Published in The Plant cell (13-05-2019)“…A cyclic nucleotide-gated, Ca 2+ channel (CNGC19) is crucial for herbivory-induced Ca 2+ influx, activation of downstream jasmonates, and aliphatic…”
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RETRACTED: The Pathogenic A116V Mutation Enhances Ion-Selective Channel Formation by Prion Protein in Membranes
Published in Biophysical journal (26-04-2016)Get full text
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The Pathogenic A116V Mutation Enhances Ion-Selective Channel Formation by Prion Protein in Membranes
Published in Biophysical journal (26-04-2016)“…Prion diseases are a group of fatal neurodegenerative disorders that afflict mammals. Misfolded and aggregated forms of the prion protein (PrP(Sc)) have been…”
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Role of Arabidopsis RAB5 GEF vps9a in maintaining potassium levels under sodium chloride stress
Published in Plant direct (01-10-2020)“…Salt stress is one of the major factors impacting crop productivity worldwide. Through a variety of effector and signaling pathways, plants achieve survival…”
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Potassium channel regulator KCNRG regulates surface expression of Shaker-type potassium channels
Published in Biochemical and biophysical research communications (15-01-2010)“…Besides their role in the generation of action potentials, voltage-gated potassium channels are implicated in cellular processes ranging from cell division to…”
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VDAC is a conserved element of death pathways in plant and animal systems
Published in Biochimica et biophysica acta (23-09-2003)“…Programmed cell death (PCD) is very much a part of plant life, although the underlying mechanisms are not so well understood as in animals. In animal cells,…”
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Solution structure of BTK-2, a novel hK v1.1 inhibiting scorpion toxin, from the eastern Indian scorpion Mesobuthus tamulus
Published in Biochimica et biophysica acta. Proteins and proteomics (2011)“…The three dimensional structure of a 32 residue three disulfide scorpion toxin, BTK-2, from the Indian red scorpion Mesobuthus tamulus has been determined…”
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Limiting cytosolic Na⁺ confers salt tolerance to rice cells in culture: a two-photon microscopy study of SBFI-loaded cells
Published in Physiologia plantarum (01-03-2007)“…Rice (Oryza sativa L.), a staple food in Asia, is very sensitive to soil salinity. However, intraspecific variations exist, with the coastal cultivar Pokkali…”
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Alamethicin and related membrane channel forming polypeptides
Published in Molecular and cellular biochemistry (01-01-1983)“…Alamethicin and several related microbial polypeptides, which contain a high proportion of alpha-aminoisobutyric acid (Aib) residues, possess the ability to…”
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Fast inactivation in potassium channels: An interplay of cytoplasmic domains
Published in Biochemical and biophysical research communications (23-10-2009)“…Fast inactivation in voltage-gated potassium channels has traditionally been associated exclusively with the N-terminus. Here, we explore the role of the T1…”
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