Search Results - "Mathew, J K"

Degradation of Cep68 and PCNT cleavage mediate Cep215 removal from the PCM to allow centriole separation, disengagement and licensing by Pagan, Julia K., Marzio, Antonio, Jones, Mathew J. K., Saraf, Anita, Jallepalli, Prasad V., Florens, Laurence, Washburn, Michael P., Pagano, Michele

“…An intercentrosomal linker keeps a cell’s two centrosomes joined together until it is dissolved at the onset of mitosis. A second connection keeps daughter…”
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Cohesin recruits the Esco1 acetyltransferase genome wide to repress transcription and promote cohesion in somatic cells by Rahman, Sadia, Jones, Mathew J. K., Jallepalli, Prasad V.

“…The cohesin complex links DNA molecules and plays key roles in the organization, expression, repair, and segregation of eukaryotic genomes. In vertebrates the…”
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T cell help controls the speed of the cell cycle in germinal center B cells by Gitlin, Alexander D., Mayer, Christian T., Oliveira, Thiago Y., Shulman, Ziv, Jones, Mathew J. K., Koren, Amnon, Nussenzweig, Michel C.

“…The germinal center (GC) is a microanatomical compartment wherein high-affinity antibody-producing B cells are selectively expanded. B cells proliferate and…”
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Chromothripsis: Chromosomes in Crisis by Jones, Mathew J.K., Jallepalli, Prasad V.

“…During oncogenesis, cells acquire multiple genetic alterations that confer essential tumor-specific traits, including immortalization, escape from…”
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Wild-Type H- and N-Ras Promote Mutant K-Ras-Driven Tumorigenesis by Modulating the DNA Damage Response by Grabocka, Elda, Pylayeva-Gupta, Yuliya, Jones, Mathew J.K., Lubkov, Veronica, Yemanaberhan, Eyoel, Taylor, Laura, Jeng, Hao Hsuan, Bar-Sagi, Dafna

“…Mutations in KRAS are prevalent in human cancers and universally predictive of resistance to anticancer therapeutics. Although it is widely accepted that…”
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Everything in Moderation: Lessons Learned by Exploiting Moderate Replication Stress in Cancer by Nazareth, Deborah, Jones, Mathew Jk, Gabrielli, Brian

“…The poor selectivity of standard cytotoxic chemotherapy regimens causes severe side-effects in patients and reduces the quality of life during treatment…”
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The Fanconi anemia pathway in replication stress and DNA crosslink repair by Jones, Mathew J. K., Huang, Tony T.

“…Interstand crosslinks (ICLs) are DNA lesions where the bases of opposing DNA strands are covalently linked, inhibiting critical cellular processes such as…”
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Early evolution of Martian volatiles: Nitrogen and noble gas components in ALH84001 and Chassigny by Mathew, K. J., Marti, K.

“…Studies on SNC meteorites have permitted the characterization of modern Martian atmospheric components as well as indigenous Martian nitrogen and solar‐type…”
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Combining accuracy and precision of traceable standards to estimate uncertainties in trace element content measurements by Schappert, M., Montoya, D., Aragon, S., Rearick, M., Xu, N., Mathew, K. J.

“…The accuracy and precision systematic of traceable certified reference material (CRM) standards can be combined to estimate the uncertainties that are achieved…”
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Comparison of the Davies and Gray titrimetric method with potassium dichromate and ceric titrants by Wylie, E. M., Colletti, L. M., Walker, L. F., Lujan, E. J. W., Garduno, K., Mathew, K. J.

“…The modified New Brunswick Laboratory (NBL) Davies and Gray titrimetry method uses potassium dichromate standard 136-f from the National Institute of Standards…”
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Patient-derived C-terminal mutation of FANCI causes protein mislocalization and reveals putative EDGE motif function in DNA repair by Colnaghi, Luca, Jones, Mathew J.K., Cotto-Rios, Xiomaris M., Schindler, Detlev, Hanenberg, Helmut, Huang, Tony T.

“…Fanconi anemia (FA) is a rare familial genome instability syndrome caused by mutations in FA genes that results in defective DNA crosslink repair. Activation…”
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Pursuing standards strategies in nuclear forensics: investigating extraction of progeny uranium in CRM-126a as a quality control material in Pu–U chronometry by Stanley, F. E., Mathew, K. J., Byerly, B. L., Keller, R., Spencer, K. J., Thomas, M. R.

“…Parent–progeny isotope relationships provide critical signatures in forensic efforts designed to determine the history of interdicted nuclear materials…”
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A Novel Corepressor, BCoR-L1, Represses Transcription through an Interaction with CtBP by Pagan, Julia K., Arnold, Jeremy, Hanchard, Kim J., Kumar, Raman, Bruno, Tiziana, Jones, Mathew J.K., Richard, Derek J., Forrest, Alistair, Spurdle, Amanda, Verdin, Eric, Crossley, Merlin, Fanciulli, Maurizio, Chenevix-Trench, Georgia, Young, David B., Khanna, Kum Kum

“…Corepressors play a crucial role in negative gene regulation and are defective in several diseases. BCoR is a corepressor for the BCL6 repressor protein. Here…”
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Uncertainties achievable for uranium isotope-amount ratios: estimates based on the precision and accuracy of recent characterization measurements by Mathew, K. J., Essex, R. M., Gradle, C., Narayanan, U.

“…Certified reference materials (CRMs) recently characterized by the NBL for isotope-amount ratios are: (i) CRM 112-A, Uranium (normal) Metal Assay and Isotopic…”
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Community perceptions of mental illness in Jharkhand, India by Sangeeta, S J, Mathew, K J

“…Introduction: Understanding and perceptions about mental illness vary among individuals based on their experience with the illness or their contact with the…”
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Xenon in the Protoplanetary Disk (PPD), in Two Planets, and a Comet by Marti, Kurt, Mathew, K. J.

“…Isotopic anomalies in several elements, as recently observed in meteorites, are generally interpreted to indicate nonequilibrium environments in the…”
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Insights into phosphorylation-dependent mechanisms regulating USP1 protein stability during the cell cycle by Cotto Rios, Xiomaris M., Jones, Mathew J.K., Huang, Tony T.

“…Tight regulation of the cell cycle and DNA repair machinery is essential for maintaining genome stability. The APC/CCdh1 ubiquitin ligase complex is a key…”
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ATR-mediated phosphorylation of FANCI regulates dormant origin firing in response to replication stress by Chen, Yu-Hung, Jones, Mathew J.K., Yin, Yandong, Crist, Sarah B., Colnaghi, Luca, Sims, Robert J., Rothenberg, Eli, Jallepalli, Prasad V., Huang, Tony T.

“…Excess dormant origins bound by the minichromosome maintenance (MCM) replicative helicase complex play a critical role in preventing replication stress,…”
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Evolutionary trends in volatiles of the nakhlite source region of Mars by Mathew, K. J., Marti, K.

“…We report new data on isotopic systematics in nitrogen, Ar, and Xe of nakhlite NWA998 and discuss the implications of nakhlite signatures on the sources,…”
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Comparison of mass spectrometric methods (TE, MTE and conventional) for uranium isotope ratio measurements by Mathew, K. J., Haoszbek, A.

“…The isotope ratio measurement techniques—total evaporation (TE), modified total evaporation (MTE), and conventional—used for characterization measurements of…”
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