Search Results - "Mathew, Bijo"

SAR Analysis of Various Heterocyclic Compounds in Medicinal Chemistry: Recent Updates-Part-I by Mathew, Bijo

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Nanoparticles and its biomedical applications in health and diseases: special focus on drug delivery by Zahin, Nuzhat, Anwar, Raihanatul, Tewari, Devesh, Kabir, Md. Tanvir, Sajid, Amin, Mathew, Bijo, Uddin, Md. Sahab, Aleya, Lotfi, Abdel-Daim, Mohamed M.

“…Nanotechnology is an emerging technology that deals with nanosized particles possessing crucial research roles and application. Disciplines like chemistry,…”
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MzDOCK: A free ready‐to‐use GUI‐based pipeline for molecular docking simulations by Kabier, Muzammil, Gambacorta, Nicola, Trisciuzzi, Daniela, Kumar, Sunil, Nicolotti, Orazio, Mathew, Bijo

“…Molecular docking is by far the most preferred approach in structure‐based drug design for its effectiveness to predict the scoring and posing of a given…”
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Advancements in nanotherapeutics for Alzheimer’s disease: current perspectives by Harilal, Seetha, Jose, Jobin, Parambi, Della Grace Thomas, Kumar, Rajesh, Mathew, Githa Elizabeth, Uddin, Md. Sahab, Kim, Hoon, Mathew, Bijo

“…Objectives Considerable progress has been made in the treatment of Alzheimer’s disease (AD), but all available strategies focus on alleviating symptoms rather…”
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Magnetic nanoparticles for hyperthermia in cancer treatment: an emerging tool by Jose, Jobin, Kumar, Rajesh, Harilal, Seetha, Mathew, Githa Elizabeth, Parambi, Della Grace Thomas, Prabhu, Ankitha, Uddin, Md. Sahab, Aleya, Lotfi, Kim, Hoon, Mathew, Bijo

“…Cancer remains as the major cause of death worldwide. The main reason why available therapies fail is that a vicious cycle in established which initiates…”
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New Aspects of Monoamine Oxidase B Inhibitors: The Key Role of Halogens to Open the Golden Door by Mathew, Bijo, Carradori, Simone, Guglielmi, Paolo, Uddin, Md Sahab, Kim, Hoon

“…A large plethora of drugs and promising lead compounds contain halogens in their structures. The introduction of such moieties strongly modulates their…”
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Recent Updates on Pyrazoline Derivatives as Promising Candidates for Neuropsychiatric and Neurodegenerative Disorders by Rangarajan, T M, Mathew, Bijo

“…Pyrazolines are five-membered heterocyclic compounds containing two nitrogen atoms that represent a privileged scaffold for various bioactive compounds with…”
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Estrogen Signaling in Alzheimer’s Disease: Molecular Insights and Therapeutic Targets for Alzheimer’s Dementia by Uddin, Md. Sahab, Rahman, Md. Motiar, Jakaria, Md, Rahman, Md. Sohanur, Hossain, Md. Sarwar, Islam, Ariful, Ahmed, Muniruddin, Mathew, Bijo, Omar, Ulfat Mohammed, Barreto, George E., Ashraf, Ghulam Md

“…Estrogens play a crucial physiological function in the brain; however, debates exist concerning the role of estrogens in Alzheimer’s disease (AD). Women during…”
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Nootropic and Anti-Alzheimer’s Actions of Medicinal Plants: Molecular Insight into Therapeutic Potential to Alleviate Alzheimer’s Neuropathology by Uddin, Md. Sahab, Al Mamun, Abdullah, Kabir, Md. Tanvir, Jakaria, Md, Mathew, Bijo, Barreto, George E., Ashraf, Ghulam Md

“…Medicinal plants are the backbone of modern medicine. In recent times, there is a great urge to discover nootropic medicinal plants to reverse cognitive…”
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Melatonin in Alzheimer’s Disease: A Latent Endogenous Regulator of Neurogenesis to Mitigate Alzheimer’s Neuropathology by Hossain, Md. Farhad, Uddin, Md. Sahab, Uddin, G. M. Sala, Sumsuzzman, Dewan Md, Islam, Md. Siddiqul, Barreto, George E., Mathew, Bijo, Ashraf, Ghulam Md

“…Melatonin, a pineal gland synthesized neurohormone is known as a multifunctioning pleiotropic agent which has a wide range of neuroprotective role in manifold…”
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Isatin-tethered halogen-containing acylhydrazone derivatives as monoamine oxidase inhibitor with neuroprotective effect by Kumar, Sunil, Oh, Jong Min, Prabhakaran, Prabitha, Awasti, Abhimanyu, Kim, Hoon, Mathew, Bijo

“…Sixteen isatin-based hydrazone derivatives ( IS1 – IS16 ) were synthesized and assessed for their ability to inhibit monoamine oxidases (MAOs). All the…”
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Combination Drug Therapy for the Management of Alzheimer's Disease by Kabir, Md Tanvir, Uddin, Md Sahab, Mamun, Abdullah Al, Jeandet, Philippe, Aleya, Lotfi, Mansouri, Rasha A, Ashraf, Ghulam Md, Mathew, Bijo, Bin-Jumah, May N, Abdel-Daim, Mohamed M

“…Alzheimer's disease (AD) is the leading cause of dementia worldwide. Even though the number of AD patients is rapidly growing, there is no effective treatment…”
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Imidazole bearing chalcones as a new class of monoamine oxidase inhibitors by Sasidharan, Rani, Baek, Seung Cheol, Sreedharannair Leelabaiamma, Manju, Kim, Hoon, Mathew, Bijo

“…In the present study, series of eleven (2E)-1-[4-(1H-imidazol-1-yl)substituted phenyl]-3-phenylprop-2-en-1-one (IM1–IM11) derivatives were synthesized and…”
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Emerging therapeutic potentials of dual‐acting MAO and AChE inhibitors in Alzheimer's and Parkinson's diseases by Mathew, Bijo, Parambi, Della G. T., Mathew, Githa E., Uddin, Md. Sahab, Inasu, Sini T., Kim, Hoon, Marathakam, Akash, Unnikrishnan, Mazhuvancherry Kesavan, Carradori, Simone

“…No drug has been approved to prevent neuronal cell loss in patients suffering from Parkinson's disease (PD) or Alzheimer's disease (AD); despite increased…”
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Toxic tau: structural origins of tau aggregation in Alzheimer's disease by Mamun, Abdullah, Uddin, Md, Mathew, Bijo, Ashraf, Ghulam

“…Alzheimer's disease is characterized by the extracellular accumulation of the amyloid β in the form of amyloid plaques and the intracellular deposition of the…”
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Molecular Insight into the Therapeutic Promise of Flavonoids against Alzheimer's Disease by Uddin, Md Sahab, Kabir, Md Tanvir, Niaz, Kamal, Jeandet, Philippe, Clément, Christophe, Mathew, Bijo, Rauf, Abdur, Rengasamy, Kannan R R, Sobarzo-Sánchez, Eduardo, Ashraf, Ghulam Md, Aleya, Lotfi

“…Alzheimer's disease (AD) is one of the utmost chronic neurodegenerative disorders, which is characterized from a neuropathological point of view by the…”
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Perillaldehyde mitigates virulence factors and biofilm formation of Pseudomonas aeruginosa clinical isolates, by acting on the quorum sensing mechanism in vitro by Benny, Anjitha Theres, Rathinam, Prasanth, Dev, Sanal, Mathew, Bijo, Radhakrishnan, Ethiraj K.

“…Aim The incidence of biofilm linked catheter‐associated urinary tract infections is increasing worldwide and Pseudomonas aeruginosa is one of the major causes…”
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TV 3326 for Alzheimer’s dementia: a novel multimodal ChE and MAO inhibitors to mitigate Alzheimer’s‐like neuropathology by Uddin, Md. Sahab, Kabir, Md. Tanvir, Rahman, Md. Motiar, Mathew, Bijo, Shah, Muhammad Ajmal, Ashraf, Ghulam Md

“…Objectives Alzheimer’s disease (AD) is one of the most prevalent neurodegenerative disorders and a well‐recognized cause of dementia with ageing. In this…”
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An efficient method to access spiro pseudoindoxyl ketones: evaluation of indoxyl and their N -benzylated derivatives for inhibition of the activity of monoamine oxidases by Perumal, Karuppaiah, Lee, Jiseong, Annes, Sesuraj Babiola, Ramesh, Subburethinam, Rangarajan, T M, Mathew, Bijo, Kim, Hoon

“…A simple, metal-free approach was developed to obtain novel pseudoindoxyl derivatives. The reaction was mediated by BuOK on tetrahydrocarbazole 8 in dimethyl…”
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Lysophosphatidic acid (LPA) receptor modulators: Structural features and recent development by Meduri, Bhagyalalitha, Pujar, Gurubasavaraj Veeranna, Durai Ananda Kumar, T., Akshatha, H.S., Sethu, Arun Kumar, Singh, Manisha, Kanagarla, Abhinav, Mathew, Bijo

“…Lysophosphatidic acid (LPA) activates six LPA receptors (LPAR1-6) and regulates various cellular activities such as cell proliferation, cytoprotection, and…”
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