Search Results - "Matheus, Filipe C."
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Periodontitis and Alzheimer's Disease: A Possible Comorbidity between Oral Chronic Inflammatory Condition and Neuroinflammation
Published in Frontiers in aging neuroscience (10-10-2017)“…Periodontitis is an oral chronic infection/inflammatory condition, identified as a source of mediators of inflammation into the blood circulation, which may…”
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Moderate-Intensity Physical Exercise Protects Against Experimental 6-Hydroxydopamine-Induced Hemiparkinsonism Through Nrf2-Antioxidant Response Element Pathway
Published in Neurochemical research (01-02-2016)“…Introduction Exercise improves the motor symptoms of patients with Parkinson disease in a palliative manner. Existing evidence demonstrates that exercise…”
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The intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a new rodent model to test palliative and neuroprotective agents for Parkinson's disease
Published in Current pharmaceutical design (01-02-2011)“…Parkinson's disease (PD) is the second most common neurodegenerative disorder affecting approximately 1% of the population older than 60 years. Classically, PD…”
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Atorvastatin improves cognitive, emotional and motor impairments induced by intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration in rats, an experimental model of Parkinson's disease
Published in Brain research (04-06-2013)“…Abstract Affective disorders and memory impairments precede the classical motor symptoms seen in Parkinson's disease (PD) and the currently approved…”
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5
Intranasal Administration of Neurotoxicants in Animals: Support for the Olfactory Vector Hypothesis of Parkinson’s Disease
Published in Neurotoxicity research (01-01-2012)“…The causes of Parkinson’s disease (PD) are unknown, but there is evidence that exposure to environmental agents, including a number of viruses, toxins,…”
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Angiotensin II type 1/adenosine A 2A receptor oligomers: a novel target for tardive dyskinesia
Published in Scientific reports (12-05-2017)“…Tardive dyskinesia (TD) is a serious motor side effect that may appear after long-term treatment with neuroleptics and mostly mediated by dopamine D receptors…”
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Single Intranasal Administration of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine in C57BL/6 Mice Models Early Preclinical Phase of Parkinson’s Disease
Published in Neurotoxicity research (01-02-2010)“…Many studies have shown that deficits in olfactory and cognitive functions precede the classical motor symptoms seen in Parkinson’s disease (PD) and that…”
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The Role of Hippocampal NMDA Receptors in Long-Term Emotional Responses following Muscarinic Receptor Activation
Published in PloS one (21-01-2016)“…Extensive evidence indicates the influence of the cholinergic system on emotional processing. Previous findings provided new insights into the underlying…”
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Adenosine A1 receptor activation modulates N-methyl-d-aspartate (NMDA) preconditioning phenotype in the brain
Published in Behavioural brain research (01-04-2015)“…•NMDA preconditioning slightly increases A1R binding affinity in the hippocampus.•NMDA preconditioning does not alter A1R levels in the hippocampus.•NMDA…”
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10
Antinociceptive and anti-inflammatory effects of the essential oil from Eremanthus erythropappus leaves
Published in Journal of pharmacy and pharmacology (01-06-2008)“…The chemical composition of the essential oil from air‐dried leaves of Eremanthus erythropappus was studied. The main compounds were β‐pinene (23.24%),…”
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11
Efficacy and tolerability of the ketogenic diet and its variations for preventing migraine in adolescents and adults: a systematic review
Published in Nutrition reviews (09-05-2022)“…Abstract Context Migraine is a headache of variable intensity that is associated with focal and systemic symptoms. A ketogenic diet (KD), a…”
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Increased ATP Release and Higher Impact of Adenosine A2A Receptors on Corticostriatal Plasticity in a Rat Model of Presymptomatic Parkinson’s Disease
Published in Molecular neurobiology (01-03-2023)“…Extracellular ATP can be a danger signal, but its role in striatal circuits afflicted in Parkinson’s disease (PD) is unclear and was now investigated. ATP was…”
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Functional interplay between adenosine A2A receptor and NMDA preconditioning in fear memory and glutamate uptake in the mice hippocampus
Published in Neurobiology of learning and memory (01-04-2021)“…•A2AR activation induces fear sensitization.•NMDA preconditioning precludes A2AR-mediated behavioral response.•A2AR activation reverses the increased glutamate…”
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Temporal Dissociation of Striatum and Prefrontal Cortex Uncouples Anhedonia and Defense Behaviors Relevant to Depression in 6-OHDA-Lesioned Rats
Published in Molecular neurobiology (01-08-2016)“…The dorsolateral striatum (DLS) processes motor and non-motor functions and undergoes extensive dopaminergic degeneration in Parkinson’s disease (PD). The…”
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Agmatine attenuates reserpine-induced oral dyskinesia in mice: Role of oxidative stress, nitric oxide and glutamate NMDA receptors
Published in Behavioural brain research (01-10-2016)“…•Orofacial antidyskinetic effects of agmatine in reserpine-treated mice.•Reserpine increased nitrite and nitrate levels in cerebral cortex of mice.•Involvement…”
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Decreased synaptic plasticity in the medial prefrontal cortex underlies short-term memory deficits in 6-OHDA-lesioned rats
Published in Behavioural brain research (15-03-2016)“…•Synaptic plasticity impairments in medial prefrontal cortex (mPFC) of 6-OHDA-lesioned rats.•6-OHDA impairs the rats performance in the novel object…”
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Neuroprotective effects of agmatine in mice infused with a single intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
Published in Behavioural brain research (01-12-2012)“…► Agmatine increased the survival rate of aging mice infused intranasally with MPTP. ► Agmatine improved social memory and motor impairments induced by i.n…”
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18
Angiotensin II type 1/adenosine A2A receptor oligomers: a novel target for tardive dyskinesia
Published in Scientific reports (12-05-2017)“…Tardive dyskinesia (TD) is a serious motor side effect that may appear after long-term treatment with neuroleptics and mostly mediated by dopamine D 2…”
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19
Anxiety in Parkinson’s disease: A critical review of experimental and clinical studies
Published in Neuropharmacology (01-01-2012)“…Parkinson’s disease (PD) is the second most common neurodegenerative disorder affecting about 1% of the population older than 60 years. Classically, PD is…”
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Mechanisms involved in abdominal nociception induced by either TRPV1 or TRPA1 stimulation of rat peritoneum
Published in European journal of pharmacology (15-08-2013)“…Abdominal pain is a frequent symptom of peritoneal cavity irritation, but little is known about the role of the receptors for irritant substances, transient…”
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