Search Results - "Matheson, Robert T"

Guselkumab (an IL-23–specific mAb) demonstrates clinical and molecular response in patients with moderate-to-severe psoriasis by Sofen, Howard, MD, Smith, Stacy, MD, Matheson, Robert T., MD, Leonardi, Craig L., MD, Calderon, Cesar, PhD, Brodmerkel, Carrie, PhD, Li, Katherine, MS, Campbell, Kim, PhD, Marciniak, Stanley J., MBA, Wasfi, Yasmine, MD, PhD, Wang, Yuhua, PhD, Szapary, Philippe, MD, Krueger, James G., MD, PhD

“…Background IL-23 expression is increased in psoriatic lesions and might regulate TH 17 T-cell counts in patients with psoriasis. Objectives We sought to test a…”
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Efficacy of apremilast in the treatment of moderate to severe psoriasis: a randomised controlled trial by Papp, Kim, Dr, Cather, Jennifer C, MD, Rosoph, Les, MD, Sofen, Howard, MD, Langley, Richard G, MD, Matheson, Robert T, MD, Hu, ChiaChi, EdM, Day, Robert M, PhD

“…Summary Background Apremilast, a small-molecule inhibitor of phosphodiesterase 4, works intracellularly to modulate proinflammatory and anti-inflammatory…”
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Evidence that a neutrophil-keratinocyte crosstalk is an early target of IL-17A inhibition in psoriasis by Reich, Kristian, Papp, Kim A., Matheson, Robert T., Tu, John H., Bissonnette, Robert, Bourcier, Marc, Gratton, David, Kunynetz, Rodion A., Poulin, Yves, Rosoph, Les A., Stingl, Georg, Bauer, Wolfgang M., Salter, Janeen M., Falk, Thomas M., Blödorn-Schlicht, Norbert A., Hueber, Wolfgang, Sommer, Ulrike, Schumacher, Martin M., Peters, Thomas, Kriehuber, Ernst, Lee, David M., Wieczorek, Grazyna A., Kolbinger, Frank, Bleul, Conrad C.

“…The response of psoriasis to antibodies targeting the interleukin (IL)‐23/IL‐17A pathway suggests a prominent role of T‐helper type‐17 (Th17) cells in this…”
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Etanercept as Monotherapy in Patients with Psoriasis by Leonardi, Craig L, Powers, Jerold L, Matheson, Robert T, Goffe, Bernard S, Zitnik, Ralph, Wang, Andrea, Gottlieb, Alice B

“…Tumor necrosis factor (TNF) is believed to have a role in the pathogenesis of psoriasis. In this 24-week randomized trial involving patients with…”
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Efficacy, tolerability, and pharmacodynamics of apremilast in recalcitrant plaque psoriasis: a phase II open-label study by Gottlieb, Alice B, Matheson, Robert T, Menter, Alan, Leonardi, Craig L, Day, Robert M, Hu, Chiachi, Schafer, Peter H, Krueger, James G

“…Apremilast, a small molecule specific inhibitor of phosphodiesterase 4, works intracellularly to modulate pro-inflammatory and anti-inflammatory mediators…”
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Topical Methyl Aminolevulinate Photodynamic Therapy Using Red Light‐Emitting Diode Light for Multiple Actinic Keratoses: A Randomized Study by SZEIMIES, ROLF‐MARKUS, MATHESON, ROBERT T., DAVIS, STEVEN A., BHATIA, ASHISH C., FRAMBACH, YVONNE, KLÖVEKORN, WINFRIED, FESQ, HEIKE, BERKING, CAROLA, REIFENBERGER, JULIA, THAÇI, DIAMANT

“…BACKGROUND Photodynamic therapy (PDT) is an effective treatment for actinic keratoses (AKs). Light‐emitting diodes (LEDs) offer practical advantages when…”
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A randomized trial of etanercept as monotherapy for psoriasis by Gottlieb, Alice B, Matheson, Robert T, Lowe, Nicholas, Krueger, Gerald G, Kang, Sewon, Goffe, Bernard S, Gaspari, Anthony A, Ling, Mark, Weinstein, Gerald D, Nayak, Anjuli, Gordon, Kenneth B, Zitnik, Ralph

“…To determine safety and efficacy of monotherapy with etanercept. Randomized, double-blind, placebo-controlled, multicenter study. Outpatient, ambulatory;…”
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Efficacy and safety of ustekinumab in patients with active psoriatic arthritis: 1 year results of the phase 3, multicentre, double-blind, placebo-controlled PSUMMIT 1 trial by McInnes, Iain B, Dr, Kavanaugh, Arthur, Prof, Gottlieb, Alice B, MD, Puig, Lluís, MD, Rahman, Proton, MD, Ritchlin, Christopher, MD, Brodmerkel, Carrie, PhD, Li, Shu, PhD, Wang, Yuhua, PhD, Mendelsohn, Alan M, MD, Doyle, Mittie K, MD

“…Summary Background Many patients with psoriasis develop psoriatic arthritis, a chronic inflammatory disease that afflicts peripheral synovial, axial, and…”
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Principles of Flexible-Use Spectrum Rights by Matheson Robert J

“…A serious problem with traditional 'command & control' spectrum management techniques is that they do not easily accommodate new technologies and new services…”
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