Search Results - "Matheson, Robert"

Guselkumab (an IL-23–specific mAb) demonstrates clinical and molecular response in patients with moderate-to-severe psoriasis by Sofen, Howard, MD, Smith, Stacy, MD, Matheson, Robert T., MD, Leonardi, Craig L., MD, Calderon, Cesar, PhD, Brodmerkel, Carrie, PhD, Li, Katherine, MS, Campbell, Kim, PhD, Marciniak, Stanley J., MBA, Wasfi, Yasmine, MD, PhD, Wang, Yuhua, PhD, Szapary, Philippe, MD, Krueger, James G., MD, PhD

“…Background IL-23 expression is increased in psoriatic lesions and might regulate TH 17 T-cell counts in patients with psoriasis. Objectives We sought to test a…”
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Efficacy of apremilast in the treatment of moderate to severe psoriasis: a randomised controlled trial by Papp, Kim, Dr, Cather, Jennifer C, MD, Rosoph, Les, MD, Sofen, Howard, MD, Langley, Richard G, MD, Matheson, Robert T, MD, Hu, ChiaChi, EdM, Day, Robert M, PhD

“…Summary Background Apremilast, a small-molecule inhibitor of phosphodiesterase 4, works intracellularly to modulate proinflammatory and anti-inflammatory…”
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Evidence that a neutrophil-keratinocyte crosstalk is an early target of IL-17A inhibition in psoriasis by Reich, Kristian, Papp, Kim A., Matheson, Robert T., Tu, John H., Bissonnette, Robert, Bourcier, Marc, Gratton, David, Kunynetz, Rodion A., Poulin, Yves, Rosoph, Les A., Stingl, Georg, Bauer, Wolfgang M., Salter, Janeen M., Falk, Thomas M., Blödorn-Schlicht, Norbert A., Hueber, Wolfgang, Sommer, Ulrike, Schumacher, Martin M., Peters, Thomas, Kriehuber, Ernst, Lee, David M., Wieczorek, Grazyna A., Kolbinger, Frank, Bleul, Conrad C.

“…The response of psoriasis to antibodies targeting the interleukin (IL)‐23/IL‐17A pathway suggests a prominent role of T‐helper type‐17 (Th17) cells in this…”
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A Randomized, Placebo-Controlled Study of SRT2104, a SIRT1 Activator, in Patients with Moderate to Severe Psoriasis by Krueger, James G, Suárez-Fariñas, Mayte, Cueto, Inna, Khacherian, Artemis, Matheson, Robert, Parish, Lawrence C, Leonardi, Craig, Shortino, Denise, Gupta, Akanksha, Haddad, Jonathan, Vlasuk, George P, Jacobson, Eric W

“…Activation of Sirtuin (silent mating type information regulation 2 homolog) 1, or SIRT1, is an unexplored therapeutic approach for treatment of inflammatory…”
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Vehicle-controlled, double-blind, randomized study of imiquimod 5% cream applied 3 days per week in one or two courses of treatment for actinic keratoses on the head by Jorizzo, Joseph, MD, Dinehart, Scott, MD, Matheson, Robert, MD, Moore, Jeffrey K., MD, Ling, Mark, MD, PhD, Fox, Terry L., MS, McRae, Scott, MS, Fielder, Sandra, MD, Lee, James H., MD, PhD

“…Background A shorter dosing regimen of imiquimod for the treatment of actinic keratosis may be effective, with long-term clinical benefits. Objective Imiquimod…”
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Etanercept as Monotherapy in Patients with Psoriasis by Leonardi, Craig L, Powers, Jerold L, Matheson, Robert T, Goffe, Bernard S, Zitnik, Ralph, Wang, Andrea, Gottlieb, Alice B

“…Tumor necrosis factor (TNF) is believed to have a role in the pathogenesis of psoriasis. In this 24-week randomized trial involving patients with…”
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Efficacy, tolerability, and pharmacodynamics of apremilast in recalcitrant plaque psoriasis: a phase II open-label study by Gottlieb, Alice B, Matheson, Robert T, Menter, Alan, Leonardi, Craig L, Day, Robert M, Hu, Chiachi, Schafer, Peter H, Krueger, James G

“…Apremilast, a small molecule specific inhibitor of phosphodiesterase 4, works intracellularly to modulate pro-inflammatory and anti-inflammatory mediators…”
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Topical Methyl Aminolevulinate Photodynamic Therapy Using Red Light‐Emitting Diode Light for Multiple Actinic Keratoses: A Randomized Study by SZEIMIES, ROLF‐MARKUS, MATHESON, ROBERT T., DAVIS, STEVEN A., BHATIA, ASHISH C., FRAMBACH, YVONNE, KLÖVEKORN, WINFRIED, FESQ, HEIKE, BERKING, CAROLA, REIFENBERGER, JULIA, THAÇI, DIAMANT

“…BACKGROUND Photodynamic therapy (PDT) is an effective treatment for actinic keratoses (AKs). Light‐emitting diodes (LEDs) offer practical advantages when…”
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20th- to 21st-Century Technological Challenges in Soft Coatings by Matheson, Robert R.

“…Coatings are among the most ancient technologies of humankind. Relatively soft coatings comprising organic materials such as blood, eggs, and extracts from…”
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Paint and coatings technology: current industrial trends by Matheson Jr, Robert R

“…General trends in industrial coatings research and development are categorized and described. Appearance, workability, durability, environmental footprint, and…”
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A techno-economic analysis of asteroid mining by Hein, Andreas M., Matheson, Robert, Fries, Dan

“…Asteroid mining has been proposed as an approach to complement Earth-based supplies of rare earth metals and to supply resources in space, such as water…”
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A randomized trial of etanercept as monotherapy for psoriasis by Gottlieb, Alice B, Matheson, Robert T, Lowe, Nicholas, Krueger, Gerald G, Kang, Sewon, Goffe, Bernard S, Gaspari, Anthony A, Ling, Mark, Weinstein, Gerald D, Nayak, Anjuli, Gordon, Kenneth B, Zitnik, Ralph

“…To determine safety and efficacy of monotherapy with etanercept. Randomized, double-blind, placebo-controlled, multicenter study. Outpatient, ambulatory;…”
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Anti–Interleukin-17 Monoclonal Antibody Ixekizumab in Chronic Plaque Psoriasis by Leonardi, Craig, Matheson, Robert, Zachariae, Claus, Cameron, Gregory, Li, Linda, Edson-Heredia, Emily, Braun, Daniel, Banerjee, Subhashis

“…In this 12-week phase 2 trial, a humanized anti–interleukin-17 monoclonal antibody was effective for chronic plaque psoriasis. Larger studies of longer…”
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Oligomers in the evolution of automotive clearcoats: mechanical performance testing as a function of exposure by Adamsons, Karlis, Blackman, Gregory, Gregorovich, Basil, Lin, Li, Matheson, Robert

“…Automotive coatings must provide excellent resistance to chemical and mechanical damage in order to maintain a vehicle's long-term appearance and the owner's…”
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Efficacy and safety of ustekinumab in patients with active psoriatic arthritis: 1 year results of the phase 3, multicentre, double-blind, placebo-controlled PSUMMIT 1 trial by McInnes, Iain B, Dr, Kavanaugh, Arthur, Prof, Gottlieb, Alice B, MD, Puig, Lluís, MD, Rahman, Proton, MD, Ritchlin, Christopher, MD, Brodmerkel, Carrie, PhD, Li, Shu, PhD, Wang, Yuhua, PhD, Mendelsohn, Alan M, MD, Doyle, Mittie K, MD

“…Summary Background Many patients with psoriasis develop psoriatic arthritis, a chronic inflammatory disease that afflicts peripheral synovial, axial, and…”
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Principles of Flexible-Use Spectrum Rights by Matheson Robert J

“…A serious problem with traditional 'command & control' spectrum management techniques is that they do not easily accommodate new technologies and new services…”
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Ultralow temperature dielectric relaxations in polyolefins by Starkweather, Howard W, Avakian, Peter, Matheson, Robert R, Fontanella, John J, Wintersgill, Mary C

“…Dielectric measurements were made on polyethylene, polypropylene, and a stabilizer, Irganox 1010, down to and below the temperature of liquid helium. All three…”
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Living polymerization: Rationale for uniform terminology by Darling, Thomas R., Davis, Thomas P., Fryd, Michael, Gridnev, Alexei A., Haddleton, David M., Ittel, Steven D., Matheson Jr, Robert R., Moad, Graeme, Rizzardo, Ezio

“…Polymer chemistry textbooks (e.g., B. Vollmert, Polymer Chemistry, Springer‐Verlag: New York, 1973, p 37; G. Odian, Principles of Polymerization, 3rd ed.,…”
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Application of acoustic materials for comfort and safety by Matheson, Robert, King, Joseph, Levit, Natalia

“…This work presents an overview of two high performance acoustic products from DuPont™ with various case studies on lowering low frequency noise transmission…”
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The technical basis for spectrum rights: Policies to enhance market efficiency by Matheson, Robert, Morris, Adele C.

“…This paper describes a conceptual framework to articulate clear rights of access to radio spectrum in a way that would foster an efficient market-based…”
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