Search Results - "Matheson, J"
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We need to talk about reliability: making better use of test-retest studies for study design and interpretation
Published in PeerJ (San Francisco, CA) (24-05-2019)“…Neuroimaging, in addition to many other fields of clinical research, is both time-consuming and expensive, and recruitable patients can be scarce. These…”
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Increased demand for NAD+ relative to ATP drives aerobic glycolysis
Published in Molecular cell (18-02-2021)“…Aerobic glycolysis, or preferential fermentation of glucose-derived pyruvate to lactate despite available oxygen, is associated with proliferation across many…”
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Strategies and Approaches of Targeting STAT3 for Cancer Treatment
Published in ACS chemical biology (19-02-2016)“…Signal transducer and activator of transcription 3 (STAT3) is a transcription factor that regulates the expression of genes related to cell cycle, cell…”
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4
Neural stem cells traffic functional mitochondria via extracellular vesicles
Published in PLoS biology (07-04-2021)“…Neural stem cell (NSC) transplantation induces recovery in animal models of central nervous system (CNS) diseases. Although the replacement of lost endogenous…”
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NOTCH1 mediates a switch between two distinct secretomes during senescence
Published in Nature cell biology (01-09-2016)“…Senescence, a persistent form of cell-cycle arrest, is often associated with a diverse secretome, which provides complex functionality for senescent cells…”
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Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells
Published in Science (American Association for the Advancement of Science) (26-06-2015)“…Forward genetic screens in Drosophila melanogaster for modifiers of position-effect variegation have revealed the basis of much of our understanding of…”
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Simultaneous multifactor Bayesian analysis (SiMBA) of PET time activity curve data
Published in NeuroImage (Orlando, Fla.) (01-08-2022)“…•SiMBA is a pharmacokinetic modelling approach for Positron Emission Tomography data.•It is a multivariate hierarchical implementation of the two-tissue…”
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Cell Surface Proteomic Map of HIV Infection Reveals Antagonism of Amino Acid Metabolism by Vpu and Nef
Published in Cell host & microbe (14-10-2015)“…Critical cell surface immunoreceptors downregulated during HIV infection have previously been identified using non-systematic, candidate approaches. To gain a…”
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Achilles Pain, Stiffness, and Muscle Power Deficits: Midportion Achilles Tendinopathy Revision 2018
Published in The journal of orthopaedic and sports physical therapy (01-05-2018)“…The Orthopaedic Section of the American Physical Therapy Association (APTA) has an ongoing effort to create evidence-based practice guidelines for orthopaedic…”
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10
XNAzymes targeting the SARS-CoV-2 genome inhibit viral infection
Published in Nature communications (16-11-2022)“…The unprecedented emergence and spread of SARS-CoV-2, the coronavirus responsible for the COVID-19 pandemic, underscores the need for diagnostic and…”
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Promiscuous Targeting of Cellular Proteins by Vpr Drives Systems-Level Proteomic Remodeling in HIV-1 Infection
Published in Cell reports (Cambridge) (30-04-2019)“…HIV-1 encodes four “accessory proteins” (Vif, Vpr, Vpu, and Nef), dispensable for viral replication in vitro but essential for viral pathogenesis in vivo. Well…”
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Low convergent validity of [11C]raclopride binding in extrastriatal brain regions: A PET study of within-subject correlations with [11C]FLB 457
Published in NeuroImage (Orlando, Fla.) (01-02-2021)“…Dopamine D2 receptors (D2-R) in extrastriatal brain regions are of high interest for research in a wide range of psychiatric and neurologic disorders…”
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D1-Dopamine Receptor Availability in First-Episode Neuroleptic Naive Psychosis Patients
Published in The international journal of neuropsychopharmacology (01-07-2019)“…Positron emission tomography studies examining differences in D1-dopamine receptor binding between control subjects and patients with schizophrenia have been…”
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Association of the DRD2 gene Taq1A polymorphism and alcoholism : a meta-analysis of case-control studies and evidence of publication bias
Published in Molecular psychiatry (01-05-2007)“…We investigated the association of the dopamine D2 receptor (DRD2) Taq1A polymorphism and alcoholism, using meta-analytic techniques, and specifically…”
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Medium-term outcomes in single anaesthetic bilateral total knee replacement surgery: a single surgeon series
Published in Archives of orthopaedic and trauma surgery (01-10-2022)“…Background The lifetime risk of developing symptomatic knee osteoarthritis (OA) is estimated to be 45%, with up to two thirds of patients presenting with…”
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A protease-activatable luminescent biosensor and reporter cell line for authentic SARS-CoV-2 infection
Published in PLoS pathogens (10-02-2022)“…Efforts to define serological correlates of protection against COVID-19 have been hampered by the lack of a simple, scalable, standardised assay for SARS-CoV-2…”
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A positron emission tomography study of the serotonin1B receptor effect of electroconvulsive therapy for severe major depressive episodes
Published in Journal of affective disorders (01-11-2021)“…•Increased 5-HT1B receptor binding after ECT for major depressive episodes.•Significant increase in 5-HT1B receptor binding in hippocampus after ECT.•Strong…”
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Diurnal and seasonal variation of the brain serotonin system in healthy male subjects
Published in NeuroImage (Orlando, Fla.) (15-05-2015)“…The mammalian circadian clock underlies both diurnal and seasonal changes in physiology, and its function is thought to be disturbed in both seasonal and…”
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Age-associated B cells predict impaired humoral immunity after COVID-19 vaccination in patients receiving immune checkpoint blockade
Published in Nature communications (27-06-2023)“…Age-associated B cells (ABC) accumulate with age and in individuals with different immunological disorders, including cancer patients treated with immune…”
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Direct Peritoneal Resuscitation Reduces Lung Injury and Caspase 8 Activity in Brain Death
Published in Journal of investigative surgery (20-10-2020)“…Background: Acute brain death (ABD) is associated with inflammation and lung injury. Direct peritoneal resuscitation (DPR) improves blood flow to the vital…”
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