Search Results - "Mathers, P H"

The Rx homeobox gene is essential for vertebrate eye development by Mathers, P. H, Grinberg, A, Mahon, K. A, Jamrich, M

“…Development of the vertebrate eye requires a series of steps including specification of the anterior neural plate, evagination of the optic vesicles from the…”
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Over-expression of miR-34a induces rapid cognitive impairment and Alzheimer’s disease-like pathology by Sarkar, S., Engler-Chiurazzi, E.B., Cavendish, J.Z., Povroznik, J.M., Russell, A.E., Quintana, D.D., Mathers, P.H., Simpkins, J.W.

“…•Sporadic Alzheimer’s disease (sAD) is difficult to model in animals.•We produced a conditional over-expressing, miR-34a mouse to model sAD.•miR-34a…”
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Regulation of eye formation by the Rx and pax6 homeobox genes by Mathers, P H, Jamrich, M

“…The Rx and pax6 homeobox genes are among the earliest genes expressed in the eye primordia and play crucial roles in the specification of ocular fate. These…”
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The role of the Rx homeobox gene in retinal progenitor proliferation and cell fate specification by Rodgers, H.M., Huffman, V.J., Voronina, V.A., Lewandoski, M., Mathers, P.H.

“…The Retinal homeobox gene (Rx; also Rax) plays a crucial role in the early development of the vertebrate eye. Germline deletion of Rx in mice results in the…”
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Vertical Bias in Dendritic Trees of Non-pyramidal Neocortical Neurons Expressing GAD67–GFP In Vitro by Jin, X., Mathers, P. H., Szabo, G., Katarova, Z., Agmon, A.

“…The neocortical neuropil has a strong vertical (orthogonal to pia) orientation, constraining the intracortical flow of information and forming the basis for…”
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Function of Rx, but not Pax6, is essential for the formation of retinal progenitor cells in mice by Zhang, Li, Mathers, Peter H., Jamrich, Milan

“…Rx plays a critical role in eye formation. Targeted elimination of Rx results in embryos that do not develop eyes. In this study, we have investigated the…”
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Sequences sufficient for correct regulation of Sgs‐3 lie close to or within the gene by Raghavan, K.V., Crosby, M.A., Mathers, P.H., Meyerowitz, E.M.

“…The Drosophila melanogaster 68C chromosomal locus is the site of a prominent polytene chromosome puff that harbors the genes Sgs‐3, Sgs‐7 and Sgs‐8. These…”
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Truncating RAX Mutations: Anophthalmia, Hypopituitarism, Diabetes Insipidus, and Cleft Palate in Mice and Men by Brachet, Cécile, Kozhemyakina, Elena A, Boros, Emese, Heinrichs, Claudine, Balikova, Irina, Soblet, Julie, Smits, Guillaume, Vilain, Catheline, Mathers, Peter H

“…Abstract Context The transcription factor RAX is a paired-type homeoprotein that plays a critical role in eye and forebrain development of vertebrate species…”
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Temporal patterns of gene expression during calyx of held development by Kolson, Douglas R., Wan, Jun, Wu, Jonathan, Dehoff, Marlin, Brandebura, Ashley N., Qian, Jiang, Mathers, Peter H., Spirou, George A.

“…ABSTRACT Relating changes in gene expression to discrete developmental events remains an elusive challenge in neuroscience, in part because most neural…”
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Initiation of Anterior Head-Specific Gene Expression in Uncommitted Ectoderm of Xenopus laevis by Ammonium Chloride by Mathers, Peter H., Miller, Andra, Doniach, Tabitha, Dirksen, Marie-Luise, Jamrich, Milan

“…The role of homeobox-containing genes in the regional specification of the vertebrate embryo has been an area of intense research over the last decade. Whereas…”
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The 68C glue puff of Drosophila by Meyerowitz, E M, Crosby, M A, Garfinkel, M D, Martin, C H, Mathers, P H, VijayRaghavan, K

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Expression of three Rx homeobox genes in embryonic and adult zebrafish by Chuang, Jui Chang, Mathers, Peter H., Raymond, Pamela A.

“…The paired-class homeobox gene, Rx, is important in eye development. In this study we analyze expression patterns of three zebrafish Rx genes ( Zrx1, 2, 3) in…”
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A trans-acting regulatory product necessary for expression of the Drosophila melanogaster 68C glue gene cluster by Crowley, T E, Mathers, P H, Meyerowitz, E M

“…The mutation l(1)npr-1 is located at cytological location 2B5 on the X chromosome in Drosophila melanogaster. We have found that this mutation causes absence…”
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Analysis of class II gene regulation by Sargent, T D, Mathers, P H

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Mutations in the human RAX homeobox gene in a patient with anophthalmia and sclerocornea by Voronina, Vera A., Kozhemyakina, Elena A., O'Kernick, Christina M., Kahn, Natan D., Wenger, Sharon L., Linberg, John V., Schneider, Adele S., Mathers, Peter H.

“…Anophthalmia and microphthalmia are among the most common ocular birth defects and a significant cause of congenital blindness. The etiology of anophthalmia…”
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Brain-Derived Neurotrophic Factor Mediates Activity-Dependent Dendritic Growth in Nonpyramidal Neocortical Interneurons in Developing Organotypic Cultures by Jin, Xiaoming, Hu, Hang, Mathers, Peter H, Agmon, Ariel

“…Brain-derived neurotrophic factor (BDNF) promotes postnatal maturation of GABAergic inhibition in the cerebral and cerebellar cortices, and its expression and…”
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Regulation of vertebrate eye development by Rx genes by Bailey, Travis J, El-Hodiri, Heithem, Zhang, Li, Shah, Rina, Mathers, Peter H, Jamrich, Milan

“…The paired-like homeobox-containing gene Rx has a critical role in the eye development of several vertebrate species including Xenopus, mouse, chicken, medaka,…”
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Expression pattern of an axolotl floor plate-specific fork head gene reflects early developmental differences between frogs and salamanders by Whiteley, Mary, Mathers, Peter H., Jamrich, Milan

“…Gastrulation is one of the most important stages of animo development and, as such, tends to be remarkably conserved. Therefore it is interesting to see that…”
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Does the brain connect before the periphery can direct? by Hoffpauir, Brian K, Marrs, Glen S, Mathers, Peter H, Spirou, George A

“…Abstract The development of peripheral to central neural connections within the auditory, visual, and olfactory systems of mice is reviewed to address whether…”
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Detection of fungi in the sinus mucosa using polymerase chain reaction by Rao, Arvin K., Mathers, Peter H., Ramadan, Hassan H.

“…To compare the presence of fungi in the sinus mucosa of patients with and without chronic rhinosinusitis. Prospective observational study using polymerase…”
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