Search Results - "Mather, William H"

A fast, robust and tunable synthetic gene oscillator by Hasty, Jeff, Stricker, Jesse, Cookson, Scott, Bennett, Matthew R, Mather, William H, Tsimring, Lev S

“…One defining goal of synthetic biology is the development of engineering-based approaches that enable the construction of gene-regulatory networks according to…”
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Translational Cross Talk in Gene Networks by Mather, William H., Hasty, Jeff, Tsimring, Lev S., Williams, Ruth J.

“…It has been shown experimentally that competition for limited translational resources by upstream mRNAs can lead to an anticorrelation between protein counts…”
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Queueing up for enzymatic processing: correlated signaling through coupled degradation by Cookson, Natalie A, Mather, William H, Danino, Tal, Mondragón‐Palomino, Octavio, Williams, Ruth J, Tsimring, Lev S, Hasty, Jeff

“…High‐throughput technologies have led to the generation of complex wiring diagrams as a post‐sequencing paradigm for depicting the interactions between vast…”
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Mechanisms for Differential Protein Production in Toxin-Antitoxin Systems by Deter, Heather S, Jensen, Roderick V, Mather, William H, Butzin, Nicholas C

“…Toxin-antitoxin (TA) systems are key regulators of bacterial persistence, a multidrug-tolerant state found in bacterial species that is a major contributing…”
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Genome-scale transcriptional dynamics and environmental biosensing by Graham, Garrett, Csicsery, Nicholas, Stasiowski, Elizabeth, Thouvenin, Gregoire, Mather, William H., Ferry, Michael, Cookson, Scott, Hasty, Jeff

“…Genome-scale technologies have enabled mapping of the complex molecular networks that govern cellular behavior. An emerging theme in the analyses of these…”
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A queueing approach to multi-site enzyme kinetics by Hochendoner, Philip, Ogle, Curtis, Mather, William H.

“…Multi-site enzymes, defined as where multiple substrate molecules can bind simultaneously to the same enzyme molecule, play a key role in a number of…”
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The spatiotemporal system dynamics of acquired resistance in an engineered microecology by Datla, Udaya Sree, Mather, William H., Chen, Sheng, Shoultz, Isaac W., Täuber, Uwe C., Jones, Caroline N., Butzin, Nicholas C.

“…Great strides have been made in the understanding of complex networks; however, our understanding of natural microecologies is limited. Modelling of complex…”
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Crosstalk between Diverse Synthetic Protein Degradation Tags in Escherichia coli by Butzin, Nicholas C, Mather, William H

“…Recently, a synthetic circuit in E. coli demonstrated that two proteins engineered with LAA tags targeted to the native protease ClpXP are susceptible to…”
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Correlation Resonance Generated by Coupled Enzymatic Processing by Mather, William H., Cookson, Natalie A., Hasty, Jeff, Tsimring, Lev S., Williams, Ruth J.

“…A major challenge for systems biology is to deduce the molecular interactions that underlie correlations observed between concentrations of different…”
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Proteolytic crosstalk in multi-protease networks by Ogle, Curtis T, Mather, William H

“…Processive proteases, such as ClpXP in E. coli, are conserved enzyme assemblies that can recognize and rapidly degrade proteins. These proteases are used for a…”
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Fast stochastic algorithm for simulating evolutionary population dynamics by Mather, William H, Hasty, Jeff, Tsimring, Lev S

“…MOTIVATION: Many important aspects of evolutionary dynamics can only be addressed through simulations. However, accurate simulations of realistically large…”
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Entrainment of a Bacterial Synthetic Gene Oscillator through Proteolytic Queueing by Butzin, Nicholas C, Hochendoner, Philip, Ogle, Curtis T, Mather, William H

“…Internal chemical oscillators (chemical clocks) direct the behavior of numerous biological systems, and maintenance of a given period and phase among many such…”
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Marching along to an Offbeat Drum: Entrainment of Synthetic Gene Oscillators by a Noisy Stimulus by Butzin, Nicholas C, Hochendoner, Philip, Ogle, Curtis T, Hill, Paul, Mather, William H

“…Modulation of biological oscillations by stimuli lies at the root of many phenomena, including maintenance of circadian rhythms, propagation of neural signals,…”
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Kinesin’s Biased Stepping Mechanism: Amplification of Neck Linker Zippering by Mather, William H., Fox, Ronald F.

“…A physically motivated model of kinesin’s motor function is developed within the framework of rectified Brownian motion. The model explains how the…”
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Universal turning point behavior for Gaussian-Klauder states and an application for maximally eccentric Rydberg atoms by Mather, William H., Fox, Ronald F.

“…Universal behavior of Gaussian-Klauder states emerges near soft classical turning points, as expressed through a complex-valued Airy transformation that…”
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Coherent-state analysis of the quantum bouncing ball by Mather, William H., Fox, Ronald F.

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Rectified Brownian motion in biology by Mather, William H

“…Nanoscale biological systems operate in the presence of overwhelming viscous drag and thermal diffusion, thus invalidating the use of macroscopically oriented…”
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Rectified Brownian motion in biology by Mather, William H

“…Nanoscale biological systems operate in the presence of overwhelming viscous drag and thermal diffusion, thus invalidating the use of macroscopically oriented…”
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Coherent-state analysis of the quantum bouncing ball by Mather, William H., Fox, Ronald F.

“…Gaussian-Klauder coherent states are applied to the bound 'quantum bouncer', a gravitating particle above an infinite potential boundary. These…”
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