Search Results - "Matharu, Daljit S"

Asymmetric Transfer Hydrogenation of CO and CN Bonds by Tethered Rh III Catalysts by Matharu, Daljit S., Martins, José E. D., Wills, Martin

“…Rh III catalysts containing a tetramethylcyclopentadienyl group linked by a ‘tether’ to a tosylated diamine ligand have previously been reported by our group…”
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Asymmetric transfer hydrogenation of C=O and C=N bonds by tethered Rh(III) catalysts by Matharu, Daljit S, Martins, José E D, Wills, Martin

“…Rh(III) catalysts containing a tetramethylcyclopentadienyl group linked by a 'tether' to a tosylated diamine ligand have previously been reported by our group…”
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Optimization of Potent and Selective Quinazolinediones: Inhibitors of Respiratory Syncytial Virus That Block RNA-Dependent RNA-Polymerase Complex Activity by Matharu, Daljit S, Flaherty, Daniel P, Simpson, Denise S, Schroeder, Chad E, Chung, Donghoon, Yan, Dan, Noah, James W, Jonsson, Colleen B, White, E. Lucile, Aubé, Jeffrey, Plemper, Richard K, Severson, William E, Golden, Jennifer E

“…A quinazolinedione-derived screening hit 2 was discovered with cellular antiviral activity against respiratory syncytial virus (CPE EC50 = 2.1 μM), moderate…”
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A Stereochemically Well-Defined Rhodium(III) Catalyst for Asymmetric Transfer Hydrogenation of Ketones by Matharu, Daljit S, Morris, David J, Kawamoto, Aparecida M, Clarkson, Guy J, Wills, Martin

“…A rhodium(III) catalyst for asymmetric transfer hydrogenation of ketones has been designed. The incorporation of a tethering group between the diamino group…”
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(S)‑N‑(2,5-Dimethylphenyl)-1-(quinoline-8-ylsulfonyl)pyrrolidine-2-carboxamide as a Small Molecule Inhibitor Probe for the Study of Respiratory Syncytial Virus Infection by Moore, Blake P, Chung, Dong Hoon, Matharu, Daljit S, Golden, Jennifer E, Maddox, Clinton, Rasmussen, Lynn, Noah, James W, Sosa, Melinda I, Ananthan, Subramaniam, Tower, Nichole, A, White, E. Lucile, Jia, Fuli, Prisinzano, Thomas E, Aubé, Jeffrey, Jonsson, Colleen B, Severson, William E

“…A high-throughput, cell-based screen was used to identify chemotypes as inhibitors for human respiratory syncytial virus (hRSV). Optimization of a…”
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Design of High-Throughput Screening Assays and Identification of a SUMO1-Specific Small Molecule Chemotype Targeting the SUMO-Interacting Motif-Binding Surface by Alontaga, Aileen Y, Li, Yifei, Chen, Chih-Hong, Ma, Chen-Ting, Malany, Siobhan, Key, Danielle E, Sergienko, Eduard, Sun, Qing, Whipple, David A, Matharu, Daljit S, Li, Baozong, Vega, Ramir, Li, Yi-Jia, Schoenen, Frank J, Blagg, Brian S. J, Chung, Thomas D.Y, Chen, Yuan

“…Protein–protein interactions are generally challenging to target by small molecules. To address the challenge, we have used a multidisciplinary approach to…”
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A cell based high-throughput screening approach for the discovery of new inhibitors of respiratory syncytial virus by Chung, Dong-Hoon, Moore, Blake P, Matharu, Daljit S, Golden, Jennifer E, Maddox, Clinton, Rasmussen, Lynn, Sosa, Melinda I, Ananthan, Subramaniam, White, E Lucile, Jia, Fuli, Jonsson, Colleen B, Severson, William E

“…Human respiratory syncytial virus (hRSV) is a highly contagious pathogen and is the most common cause of bronchiolitis and pneumonia for infants and children…”
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High-throughput screening identifies a bisphenol inhibitor of SV40 large T antigen ATPase activity by Seguin, Sandlin P, Evans, Carrie W, Nebane-Akah, Miranda, McKellip, Sara, Ananthan, Subramaniam, Tower, Nichole A, Sosa, Melinda, Rasmussen, Lynn, White, E Lucile, Maki, Brooks E, Matharu, Daljit S, Golden, Jennifer E, Aubé, Jeffrey, Brodsky, Jeffrey L, Noah, James W

“…The authors conducted a high-throughput screening campaign for inhibitors of SV40 large T antigen ATPase activity to identify candidate antivirals that target…”
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Asymmetric Transfer Hydrogenation of CO and CN Bonds by Tethered RhIII Catalysts by Matharu, Daljit S., Martins, José E. D., Wills, Martin

“…RhIII catalysts containing a tetramethylcyclopentadienyl group linked by a ‘tether’ to a tosylated diamine ligand have previously been reported by our group…”
Get full text