Search Results - "Matevska, Nadica"
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Loss of Y Chromosome in Peripheral Blood of Colorectal and Prostate Cancer Patients
Published in PloS one (08-01-2016)“…Although age-related loss of chromosome Y (LOY) in normal hematopoietic cells is a well-known phenomenon, the phenotypic consequences of LOY have been elusive…”
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The impact of molecular tumor profiling on the design strategies for targeting myeloid leukemia and EGFR/CD44-positive solid tumors
Published in Beilstein journal of nanotechnology (29-04-2021)“…Nanomedicine has emerged as a novel cancer treatment and diagnostic modality, whose design constantly evolves towards increasing the safety and efficacy of the…”
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3
AKR1D136 C>T (rs1872930) allelic variant is associated with variability of the CYP2C9 genotype predicted pharmacokinetics of ibuprofen enantiomers – a pilot study in healthy volunteers
Published in Acta Pharmaceutica (01-09-2019)“…The relative contribution of CYP2C9 allelic variants to the pharmacokinetics (PK) of ibuprofen (IBP) enantiomers has been studied extensively, but the…”
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Efficacy assessment of self-assembled PLGA-PEG-PLGA nanoparticles: Correlation of nano-bio interface interactions, biodistribution, internalization and gene expression studies
Published in International journal of pharmaceutics (30-11-2017)“…[Display omitted] The aim of our study was to develop and compare the biological performance of two types of biodegradable SN-38 loaded nanoparticles (NPs)…”
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Review: Occult hepatitis C virus infection: Still remains a controversy
Published in Journal of medical virology (01-09-2014)“…Occult hepatitis C virus (HCV) infection is characterized by the presence of HCV RNA in the liver cells or peripheral blood mononuclear cells of the patients…”
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The association of C3435T single-nucleotide polymorphism, Pgp-glycoprotein gene expression levels and carbamazepine maintenance dose in patients with epilepsy
Published in Neuropsychiatric disease and treatment (01-01-2012)“…The ABCB1 gene encodes the P-glycoprotein (Pgp) protein, which is thought to transport various antiepileptic drugs. The single nucleotide polymorphism (SNP)…”
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7
The AKR1D136 ( rs1872930 ) Allelic Variant Is Independently Associated With Clopidogrel Treatment Outcome
Published in Pharmacogenomics and personalized medicine (01-01-2019)“…The present observational cohort study evaluated the association between the (rs1872930) allele and the risk of major adverse cardiovascular and…”
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Genetic predictors of the response to the treatment of hepatitis C virus infection
Published in Biomolecules & biomedicine (12-11-2015)“…The genome-wide association studies have identified a strong association between interleukin 28B (IL28B) gene polymorphisms and the response to treatment in…”
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Overlooking MMR deficiency in carriers of certain pathogenic variants by routine MSI and/or IHC testing in Lynch syndrome: Implications for a wider MMR deficiency testing
Published in Journal of clinical oncology (20-05-2020)“…Abstract only e16107 Background: DNA mismatch repair (MMR) deficiency occurs in both inherited/sporadic colorectal cancer (CRC) and endometrial cancer, but it…”
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10
Increased oxidative/nitrosative stress and decreased antioxidant enzyme activities in prostate cancer
Published in Clinical biochemistry (01-08-2009)“…The study was aimed to evaluate the oxidative/nitrosative stress status in prostate cancer (CaP) and benign prostatic hyperplasia (BPH). 312 men from two…”
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Molecular monitoring as a useffull tool in acute myeloid leukemia patients undergoing matched unrelated donor - hematopoietic stem cell transplantation : republic of north macedonia experience
Published in Hematology reports (01-09-2020)“…Introduction: Minimal residual disease (MRD) in acute myeloid leukemia (AML) cases is a complex, multi-modality assessment and much as its clinical…”
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12
Search for the presence of occult hepatitis C in patients with treatment-induced viral clearance using an ultrasensitive assay
Published in Srpski arhiv za celokupno lekarstvo (01-07-2016)“…Occult hepatitis C is defined by the presence of virus in the peripheral blood mononuclear cells (PBMCs) and/or liver cells, in the absence of serum viremia…”
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Correlation of Somatic Mutations and Clinical Characteristics at Presentation in Patients with Essential Thrombocytemia
Published in Blood (06-12-2014)“…Background Most patients with essential thromocythemia (ET) have somatic mutations in janus kinase 2 (JAK2), calreticulin (CALR) and thrombopoietin receptor…”
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Glutathione peroxidase 1 (GPX1) genetic polymorphism, erythrocyte GPX activity, and prostate cancer risk
Published in International urology and nephrology (2009)“…Glutathione peroxidase 1 (GPX1) is a ubiquitously expressed selenium-dependent enzyme that protects cells against oxidative damage by reducing hydrogen…”
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Frequency and Clinical Correlates of JAK2 46/1 Haplotype in Comparison with JAK2V617F Variant in Myeloproliferative Neoplasms: Single Center Experience
Published in Blood (18-11-2011)“…Abstract 5173 It is predicted that the inherited genetic background in the individual patients with myeloproliferative neoplasm (MPN) influences the disease…”
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P-0265 Msi+ Stage II/III Colon Cancer Patients Benefit from Capecitabine Adjuvant Monotherapy
Published in Annals of oncology (01-06-2012)Get full text
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Promoter length polymorphism in UGT1A1 and the risk of sporadic colorectal cancer
Published in Cancer genetics (01-04-2012)“…Uridine diphosphoglucuronate glucuronosyltransferase 1A1 (UGT1A1) is the key hepatic detoxification enzyme involved in the biotransformation of many…”
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Variants of unknown significance (VUS) in patients with hereditary CRC without a known pathogenic variant
Published in Journal of clinical oncology (01-06-2022)“…10599 Background: Nearly 5-10% of all newly diagnosed colorectal cancer (CRC) cases develop due to the presence of a highly penetrant pathogenic variant in one…”
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Analysis of TSHZ2 and TSHZ3 genes in congenital pelvi-ureteric junction obstruction
Published in Nephrology, dialysis, transplantation (01-01-2010)“…Background. Congenital pelvi-ureteric junction obstruction (PUJO) affects 0.3% of human births. It may result from aberrant smooth muscle development in the…”
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Association between Gene Polymorphism of Manganese Superoxide Dismutase and Prostate Cancer Risk
Published in Journal of biochemical and molecular toxicology (01-03-2013)“…ABSTRACT Manganese superoxide dismutase (MnSOD) is the most effective antioxidant enzyme in mitochondria and protects cells from reactive oxygen…”
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