Search Results - "Matesanz, Ana I"
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Palladium(II) and platinum(II) bis(thiosemicarbazone) complexes of the 2,6-diacetylpyridine series with high cytotoxic activity in cisplatin resistant A2780cisR tumor cells and reduced toxicity
Published in Journal of inorganic biochemistry (01-08-2013)“…Preparation and characterization of four novel 2,6-diacetylpyridine bis(4N-tolylthiosemicarbazonato) palladium(II) and platinum(II) complexes, [PdL1–2] and…”
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New palladium and platinum complexes with bioactive 3,5-diacetyl-1,2,4-triazol bis(4-cyclohexyl thiosemicarbazone) ligand: chemistry, antiproliferative activity and preliminary toxicity studies
Published in Dalton transactions : an international journal of inorganic chemistry (28-10-2012)“…The preparation and characterization of the new 3,5-diacetyl-1,2,4-triazol bis(4-cyclohexyl thiosemicarbazone) ligand, H(5)L(1), is described. Treatment of…”
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Proving the Antimicrobial Therapeutic Activity on a New Copper–Thiosemicarbazone Complex
Published in Molecular pharmaceutics (01-04-2024)“…The misuse and overdose of antimicrobial medicines are fostering the emergence of novel drug-resistant pathogens, providing negative repercussions not only on…”
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A select thiosemicarbazone copper(II) complex induces apoptosis in gastric cancer and targets cancer stem cells reducing pluripotency markers
Published in European journal of medicinal chemistry (15-12-2024)“…Copper(II)-based complexes are promising candidates as anti-cancer agents due to their ability to target cancer cells. Here we describe the synthesis and…”
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New Platinum(II) Triazole Thiosemicarbazone Complexes: Analysis of Their Reactivity and Potential Antitumoral Action
Published in Chembiochem : a European journal of chemical biology (17-04-2020)“…The synthesis and characterization of three new platinum complexes, with 3,5‐diacetyl‐1,2,4‐triazole bis(4‐N‐isopropylthiosemicarbazone) as a ligand, are…”
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Exploring DNA binding ability of two novel α-N-heterocyclic thiosemicarbazone palladium(II) complexes
Published in Journal of inorganic biochemistry (01-02-2020)“…One mononuclear and another dinuclear Pd(II) complexes bearing a α-N-heterocyclic thiosemicarbazone ligand have been synthesized, fully characterized and…”
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Dithiobiureas Palladium(II) complexes' studies: From their synthesis to their biological action
Published in Journal of inorganic biochemistry (01-09-2023)“…Dithiobiureas coordination chemistry towards palladium (II) ions and their possible application is presented and discussed…”
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Versatile Route to trans-Platinum(II) Complexes via Manipulation of a Coordinated 3‑(Pyridin-3-yl)propanoic Acid Ligand
Published in Inorganic chemistry (03-06-2019)“…We describe the direct coupling of alcohols and amines to a 3-(pyridin-3-yl)propanoic acid ligand coordinated to a Pt(II) to afford ester and amide…”
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Thiosemicarbazone Derivatives as Inhibitors of Amyloid‑β Aggregation: Effect of Metal Coordination
Published in Inorganic chemistry (18-05-2020)“…Three thiosemicarbazone derivatives, namely 4-(dimethylamino)benzaldehyde 4,4-dimethylthiosemicarbazone (HL 1 ), 4-(dimethylamino)benzaldehyde…”
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3,5-Diacetyl-1,2,4-triazol bis( 4N-substituted thiosemicarbazone) palladium(II) complexes: Synthesis, structure, antiproliferative activity and low toxicity on normal kidney cells
Published in Journal of inorganic biochemistry (01-12-2011)“…Treatment of 4 N-monosubstituted bis(thiosemicarbazone) ligands of 3,5-diacetyl-1,2,4-triazol series with lithium tetrachloridopalladate gave the dinuclear…”
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New bioactive 2,6-diacetylpyridine bis(p-chlorophenylthiosemicarbazone) ligand and its Pd(II) and Pt(II) complexes: Synthesis, characterization, cytotoxic activity and DNA binding ability
Published in Journal of inorganic biochemistry (01-09-2014)“…Preparation and characterization of 2,6-diacetylpyridine bis(4N-p-chlorophenylthiosemicarbazone) ligand, H2L, and its palladium(II) and platinum(II) complexes…”
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Two Different Thiosemicarbazone Tauto‐Conformers Coordinate to Palladium (II). Stability and Biological Studies of the Final Complexes
Published in European journal of inorganic chemistry (19-03-2021)“…Thiosemicarbazone moiety is a valuable scaffold for the synthesis of metallic complexes with anticancer purposes, when bearing N‐heterocyclic the final…”
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Novel bis(thiosemicarbazones) of the 3,5-diacetyl-1,2,4-triazol series and their platinum(II) complexes: chemistry, antiproliferative activity and preliminary nephrotoxicity studies
Published in Dalton transactions : an international journal of inorganic chemistry (07-06-2011)“…The preparation and characterization of three novel (4)N-monosubstituted bis(thiosemicarbazone) ligands of 3,5-diacetyl-1,2,4-triazol series and their…”
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alpha-N-heterocyclic thiosemicarbazone derivatives as potential antitumor agents: a structure-activity relationships approach
Published in Mini reviews in medicinal chemistry (01-10-2009)“…alpha-N-Heterocyclic thiosemicarbazones, (N)-TSCs, are potent inhibitors of ribonucleotide reductase (RR). This enzyme plays a critical role in DNA synthesis…”
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Novel cyclopalladated and coordination palladium and platinum complexes derived from alpha-diphenyl ethanedione bis(thiosemicarbazones): structural studies and cytotoxic activity against human A2780 and A2780cisR carcinoma cell lines
Published in Journal of inorganic biochemistry (01-10-2007)“…The preparation of new palladium(II) and platinum(II) complexes derived from alpha-diphenyl ethanedione bis(thiosemicarbazone), 1, and alpha-diphenyl…”
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Novel structures of platinum complexes bearing N‑bisphosphonates and study of their biological properties
Published in Journal of inorganic biochemistry (01-02-2019)“…Novel bisphosphonate platinum complexes: [Pt(isopropylamine)2(BP)]NO3 (BP = pamidronate and alendronate) have been synthesized and characterized. Their…”
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Palladium and platinum 3,5-diacetyl-1,2,4-triazol bis(thiosemicarbazones): Chemistry, cytotoxic activity and structure–activity relationships
Published in Journal of inorganic biochemistry (01-02-2007)“…The preparation of platinum(II) complexes derived from 3,5-diacetyl-1,2,4-triazol bis(4-phenylthiosemicarbazone) (H 5L 1), 3,5-diacetyl-1,2,4-triazol…”
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Chemistry, antiproliferative activity and low nephrotoxicity of 3,5-diacetyl-1,2,4-triazol bis(4N-thiosemicarbazone) ligands and their platinum(II) complexes
Published in Dalton transactions : an international journal of inorganic chemistry (14-08-2010)“…The preparation and characterization of 3,5-diacetyl-1,2,4-triazol bis(4,4-dimethylthiosemicarbazone) ligand, H(3)L(1), and its dinuclear platinum complex…”
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Toxic effects of bis(thiosemicarbazone) compounds and its palladium(II) complexes on herpes simplex virus growth
Published in Toxicology and applied pharmacology (01-06-2004)“…Here, we present data on the activity of benzyl bis(thiosemicarbazone); 3,5-diacyl-1,2,4-triazole bis(4-methylthiosemicarbazone) and their Pd(II) complexes…”
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Synthesis, Reactivity Studies, and Cytotoxicity of Two trans-Iodidoplatinum(II) Complexes. Does Photoactivation Work?
Published in Inorganics (01-12-2018)“…trans-Platinum complexes have been the landmark in unconventional drugs prompting the development of innovative structures that might exhibit chemical and…”
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