Search Results - "Matesanz, Ana"

alpha-N-heterocyclic thiosemicarbazone derivatives as potential antitumor agents: a structure-activity relationships approach by Matesanz, Ana I, Souza, Pilar

“…alpha-N-Heterocyclic thiosemicarbazones, (N)-TSCs, are potent inhibitors of ribonucleotide reductase (RR). This enzyme plays a critical role in DNA synthesis…”
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Palladium(II) and platinum(II) bis(thiosemicarbazone) complexes of the 2,6-diacetylpyridine series with high cytotoxic activity in cisplatin resistant A2780cisR tumor cells and reduced toxicity by Matesanz, Ana I., Leitao, Inés, Souza, Pilar

“…Preparation and characterization of four novel 2,6-diacetylpyridine bis(4N-tolylthiosemicarbazonato) palladium(II) and platinum(II) complexes, [PdL1–2] and…”
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Thiosemicarbazone Derivatives as Inhibitors of Amyloid‑β Aggregation: Effect of Metal Coordination by Matesanz, Ana I, Caballero, Ana B, Lorenzo, Carmen, Espargaró, Alba, Sabaté, Raimon, Quiroga, Adoración G, Gamez, Patrick

“…Three thiosemicarbazone derivatives, namely 4-(dimethylamino)­benzaldehyde 4,4-dimethylthiosemicarbazone (HL 1 ), 4-(dimethylamino)­benzaldehyde…”
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New palladium and platinum complexes with bioactive 3,5-diacetyl-1,2,4-triazol bis(4-cyclohexyl thiosemicarbazone) ligand: chemistry, antiproliferative activity and preliminary toxicity studies by Matesanz, Ana I, Perles, Josefina, Souza, Pilar

“…The preparation and characterization of the new 3,5-diacetyl-1,2,4-triazol bis(4-cyclohexyl thiosemicarbazone) ligand, H(5)L(1), is described. Treatment of…”
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Proving the Antimicrobial Therapeutic Activity on a New Copper–Thiosemicarbazone Complex by Fabra, David, Amariei, Georgiana, Ruiz-Camino, Daniel, Matesanz, Ana I., Rosal, Roberto, Quiroga, Adoracion G., Horcajada, Patricia, Hidalgo, Tania

“…The misuse and overdose of antimicrobial medicines are fostering the emergence of novel drug-resistant pathogens, providing negative repercussions not only on…”
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A select thiosemicarbazone copper(II) complex induces apoptosis in gastric cancer and targets cancer stem cells reducing pluripotency markers by Fabra, David, Melones-Herrero, Jorge, Velazquez-Gutierrez, Javier, Matesanz, Ana I., Aliseda, Patricia D., Figueiras, Sofia, Aguilar-Rico, Francisco, Calés, Carmela, Sánchez-Pérez, Isabel, Quiroga, Adoracion G.

“…Copper(II)-based complexes are promising candidates as anti-cancer agents due to their ability to target cancer cells. Here we describe the synthesis and…”
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New Platinum(II) Triazole Thiosemicarbazone Complexes: Analysis of Their Reactivity and Potential Antitumoral Action by Matesanz, Ana I., Herrero, Jorge M., Faraco, Eva J., Cubo, Leticia, Quiroga, Adoracion G.

“…The synthesis and characterization of three new platinum complexes, with 3,5‐diacetyl‐1,2,4‐triazole bis(4‐N‐isopropylthiosemicarbazone) as a ligand, are…”
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Exploring DNA binding ability of two novel α-N-heterocyclic thiosemicarbazone palladium(II) complexes by Fuentes, Lidia, Quiroga, Adoración G., Organero, Juan A., Matesanz, Ana I.

“…One mononuclear and another dinuclear Pd(II) complexes bearing a α-N-heterocyclic thiosemicarbazone ligand have been synthesized, fully characterized and…”
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Dithiobiureas Palladium(II) complexes' studies: From their synthesis to their biological action by Herrero, Jorge M., Fabra, David, Matesanz, Ana I., Hernández, Carolina, Sánchez-Pérez, Isabel, Quiroga, Adoracion G.

“…Dithiobiureas coordination chemistry towards palladium (II) ions and their possible application is presented and discussed…”
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Versatile Route to trans-Platinum(II) Complexes via Manipulation of a Coordinated 3‑(Pyridin-3-yl)propanoic Acid Ligand by Cabrera, Silvia, Navas, Francisco, Matesanz, Ana I, Maroto, Marta, Riedel, Tina, Dyson, Paul J, Quiroga, Adoracion G

“…We describe the direct coupling of alcohols and amines to a 3-(pyridin-3-yl)­propanoic acid ligand coordinated to a Pt­(II) to afford ester and amide…”
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Novel structures of platinum complexes bearing N‑bisphosphonates and study of their biological properties by Alvarez-Valdes, Amparo, Matesanz, Ana I., Perles, Josefina, Fernandes, Célia, Correia, João D.G., Mendes, Filipa, Quiroga, Adoracion G.

“…Novel bisphosphonate platinum complexes: [Pt(isopropylamine)2(BP)]NO3 (BP = pamidronate and alendronate) have been synthesized and characterized. Their…”
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3,5-Diacetyl-1,2,4-triazol bis( 4N-substituted thiosemicarbazone) palladium(II) complexes: Synthesis, structure, antiproliferative activity and low toxicity on normal kidney cells by Matesanz, Ana I., Hernández, Carolina, Rodríguez, Ana, Souza, Pilar

“…Treatment of 4 N-monosubstituted bis(thiosemicarbazone) ligands of 3,5-diacetyl-1,2,4-triazol series with lithium tetrachloridopalladate gave the dinuclear…”
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New bioactive 2,6-diacetylpyridine bis(p-chlorophenylthiosemicarbazone) ligand and its Pd(II) and Pt(II) complexes: Synthesis, characterization, cytotoxic activity and DNA binding ability by Matesanz, Ana I., Hernández, Carolina, Souza, Pilar

“…Preparation and characterization of 2,6-diacetylpyridine bis(4N-p-chlorophenylthiosemicarbazone) ligand, H2L, and its palladium(II) and platinum(II) complexes…”
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Two Different Thiosemicarbazone Tauto‐Conformers Coordinate to Palladium (II). Stability and Biological Studies of the Final Complexes by Fabra, David, Matesanz, Ana I., Herrero, Jorge M., Alvarez, Cristina, Balsa, Lucia M., Leon, Ignacio E., Quiroga, Adoracion G.

“…Thiosemicarbazone moiety is a valuable scaffold for the synthesis of metallic complexes with anticancer purposes, when bearing N‐heterocyclic the final…”
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Preparation and Characterization of Plasma-Derived Fibrin Hydrogels Modified by Alginate di-Aldehyde by Sanz-Horta, Raúl, Matesanz, Ana, Jorcano, José Luis, Velasco, Diego, Acedo, Pablo, Gallardo, Alberto, Reinecke, Helmut, Elvira, Carlos

“…Fibrin hydrogels are one of the most popular scaffolds used in tissue engineering due to their excellent biological properties. Special attention should be…”
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Novel bis(thiosemicarbazones) of the 3,5-diacetyl-1,2,4-triazol series and their platinum(II) complexes: chemistry, antiproliferative activity and preliminary nephrotoxicity studies by Matesanz, Ana I, Hernández, Carolina, Rodríguez, Ana, Souza, Pilar

“…The preparation and characterization of three novel (4)N-monosubstituted bis(thiosemicarbazone) ligands of 3,5-diacetyl-1,2,4-triazol series and their…”
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Technological advances in fibrin for tissue engineering by Sanz-Horta, Raúl, Matesanz, Ana, Gallardo, Alberto, Reinecke, Helmut, Jorcano, José Luis, Acedo, Pablo, Velasco, Diego, Elvira, Carlos

“…Fibrin is a promising natural polymer that is widely used for diverse applications, such as hemostatic glue, carrier for drug and cell delivery, and matrix for…”
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Novel cyclopalladated and coordination palladium and platinum complexes derived from alpha-diphenyl ethanedione bis(thiosemicarbazones): structural studies and cytotoxic activity against human A2780 and A2780cisR carcinoma cell lines by Matesanz, Ana I, Souza, Pilar

“…The preparation of new palladium(II) and platinum(II) complexes derived from alpha-diphenyl ethanedione bis(thiosemicarbazone), 1, and alpha-diphenyl…”
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Palladium and platinum 3,5-diacetyl-1,2,4-triazol bis(thiosemicarbazones): Chemistry, cytotoxic activity and structure–activity relationships by Matesanz, Ana I., Souza, Pilar

“…The preparation of platinum(II) complexes derived from 3,5-diacetyl-1,2,4-triazol bis(4-phenylthiosemicarbazone) (H 5L 1), 3,5-diacetyl-1,2,4-triazol…”
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Chemistry, antiproliferative activity and low nephrotoxicity of 3,5-diacetyl-1,2,4-triazol bis(4N-thiosemicarbazone) ligands and their platinum(II) complexes by Matesanz, Ana I, Joie, Céline, Souza, Pilar

“…The preparation and characterization of 3,5-diacetyl-1,2,4-triazol bis(4,4-dimethylthiosemicarbazone) ligand, H(3)L(1), and its dinuclear platinum complex…”
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