Search Results - "Mateos, Maria"
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Carfilzomib, dexamethasone, and daratumumab versus carfilzomib and dexamethasone for patients with relapsed or refractory multiple myeloma (CANDOR): results from a randomised, multicentre, open-label, phase 3 study
Published in The Lancet (British edition) (18-07-2020)“…Lenalidomide and bortezomib frontline exposure has raised a growing need for novel treatments for patients with relapsed or refractory multiple myeloma…”
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2
Multiple myeloma: patient outcomes in real‐world practice
Published in British journal of haematology (01-10-2016)“…Summary With increasing number of therapies available for the treatment of multiple myeloma, it is timely to examine the course of patients' journeys. We…”
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3
Daratumumab plus pomalidomide and dexamethasone versus pomalidomide and dexamethasone alone in previously treated multiple myeloma (APOLLO): an open-label, randomised, phase 3 trial
Published in The lancet oncology (01-06-2021)“…In a phase 1b study, intravenous daratumumab plus pomalidomide and dexamethasone induced a very good partial response or better rate of 42% and was well…”
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4
Clinical features associated with COVID-19 outcome in multiple myeloma: first results from the International Myeloma Society data set
Published in Blood (24-12-2020)“…The primary cause of morbidity and mortality in patients with multiple myeloma (MM) is an infection. Therefore, there is great concern about susceptibility to…”
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Maintenance therapy with bortezomib plus thalidomide or bortezomib plus prednisone in elderly multiple myeloma patients included in the GEM2005MAS65 trial
Published in Blood (27-09-2012)“…Maintenance therapy has become a hot field in myeloma, and it may be particularly relevant in elderly patients because the major benefit results from the…”
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6
GEM2005 trial update comparing VMP/VTP as induction in elderly multiple myeloma patients: do we still need alkylators?
Published in Blood (18-09-2014)“…Melphalan (M), in combination with prednisone (MP), has been the backbone of new combinations, including bortezomib plus MP (VMP). However, new alkylator-free…”
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Overall survival with daratumumab, bortezomib, melphalan, and prednisone in newly diagnosed multiple myeloma (ALCYONE): a randomised, open-label, phase 3 trial
Published in The Lancet (British edition) (11-01-2020)“…Standard-of-care treatment for patients with newly diagnosed multiple myeloma includes combination therapies for patients who are not eligible for autologous…”
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Treatment of multiple myeloma with high-risk cytogenetics: a consensus of the International Myeloma Working Group
Published in Blood (16-06-2016)“…The International Myeloma Working Group consensus updates the definition for high-risk (HR) multiple myeloma based on cytogenetics Several cytogenetic…”
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Bortezomib, Melphalan, and Dexamethasone for Light-Chain Amyloidosis
Published in Journal of clinical oncology (01-10-2020)“…Oral melphalan and dexamethasone (MDex) were considered a standard of care in light-chain (AL) amyloidosis. In the past decade, bortezomib has been…”
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Prevention and management of adverse events during treatment with bispecific antibodies and CAR T cells in multiple myeloma: a consensus report of the European Myeloma Network
Published in The lancet oncology (01-06-2023)“…T-cell redirecting bispecific antibodies (BsAbs) and chimeric antigen receptor T cells (CAR T cells) have revolutionised multiple myeloma therapy, but adverse…”
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11
Elotuzumab plus lenalidomide/dexamethasone for relapsed or refractory multiple myeloma: ELOQUENT‐2 follow‐up and post‐hoc analyses on progression‐free survival and tumour growth
Published in British journal of haematology (01-09-2017)“…Summary The randomized phase III ELOQUENT‐2 study (NCT01239797) evaluated the efficacy and safety of elotuzumab + lenalidomide/dexamethasone (ELd) versus…”
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12
Sustained minimal residual disease negativity in newly diagnosed multiple myeloma and the impact of daratumumab in MAIA and ALCYONE
Published in Blood (27-01-2022)“…In patients with transplant-ineligible newly diagnosed multiple myeloma (NDMM), daratumumab reduced the risk of disease progression or death by 44% in MAIA…”
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13
Efficacy and safety of cilta-cel in patients with progressive multiple myeloma after exposure to other BCMA-targeting agents
Published in Blood (19-01-2023)“…•Cilta-cel, a BCMA-targeting chimeric antigen receptor−T-cell therapy, induced clinical responses in patients previously exposed to noncellular anti-BCMA…”
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14
Teclistamab in Relapsed or Refractory Multiple Myeloma
Published in The New England journal of medicine (11-08-2022)“…In this phase 1–2 study involving patients with relapsed or refractory myeloma, a bispecific antibody (teclistamab) that mediates T-cell activation and…”
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Prognostic value of deep sequencing method for minimal residual disease detection in multiple myeloma
Published in Blood (15-05-2014)“…We assessed the prognostic value of minimal residual disease (MRD) detection in multiple myeloma (MM) patients using a sequencing-based platform in bone marrow…”
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16
Carfilzomib, dexamethasone, and daratumumab versus carfilzomib and dexamethasone for patients with relapsed or refractory multiple myeloma (CANDOR): updated outcomes from a randomised, multicentre, open-label, phase 3 study
Published in The lancet oncology (01-01-2022)“…Despite recent advances in therapeutic options, there remains an unmet need for treating patients with relapsed or refractory multiple myeloma, especially in…”
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Phase Ib Study of Panobinostat and Bortezomib in Relapsed or Relapsed and Refractory Multiple Myeloma
Published in Journal of clinical oncology (10-10-2013)“…Despite advancements, prognosis for patients with relapsed/refractory multiple myeloma (MM) is poor, and novel therapies are needed. Panobinostat is a potent…”
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18
Elotuzumab Therapy for Relapsed or Refractory Multiple Myeloma
Published in The New England journal of medicine (13-08-2015)“…The addition of elotuzumab (a monoclonal antibody against SLAMF7) to lenalidomide plus dexamethasone produced a significant increase in progression-free…”
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Melflufen and Dexamethasone in Heavily Pretreated Relapsed and Refractory Multiple Myeloma
Published in Journal of clinical oncology (01-03-2021)“…Melphalan flufenamide (melflufen) is a first-in-class peptide-drug conjugate that targets aminopeptidases and rapidly and selectively releases alkylating…”
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How I treat triple‐class refractory multiple myeloma
Published in British journal of haematology (01-07-2022)“…Immunomodulatory imide drugs (IMiDs), proteasome inhibitors (PIs) and anti‐CD38 monoclonal antibodies (MoAbs) are the pillars of modern multiple myeloma (MM)…”
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