Critical Comparison of 31 Commercially Available Digital Slide Systems in Pathology

Advances in new technologies for complete slide digitization in pathology have allowed the appearance of a wide spectrum of technologic solutions for whole-slide scanning, which have been classified into motorized microscopes and scanners. This article describes technical aspects of 31 different dig...

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Bibliographic Details
Published in:	International journal of surgical pathology Vol. 14; no. 4; pp. 285 - 305
Main Authors:	Rojo, Marcial García, García, Gloria Bueno, Mateos, Carlos Peces, García, Jesús González, Vicente, Manuel Carbajo
Format:	Journal Article
Language:	English
Published:	Thousand Oaks, CA SAGE Publications 01-10-2006
Subjects:	Equipment Design Histological Techniques - instrumentation Histological Techniques - methods Humans Image Processing, Computer-Assisted - instrumentation Image Processing, Computer-Assisted - methods Microscopy - instrumentation Microscopy - methods Pathology - instrumentation Pathology - methods Signal Processing, Computer-Assisted whole slide scanning motorized microscope virtual microscopy
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Summary:	Advances in new technologies for complete slide digitization in pathology have allowed the appearance of a wide spectrum of technologic solutions for whole-slide scanning, which have been classified into motorized microscopes and scanners. This article describes technical aspects of 31 different digital microscopy systems. The most relevant characteristics of the scanning devices are described, including the cameras used, the speed of digitization, and the image quality. Other aspects, such as the file format, the compression techniques, and the solutions for visualization of digital slides, (including diagnosis-aided tools) are also considered. Most of the systems evaluated allow a high-resolution digitization of the whole slide within about 1 hour using a ×40 objective. The image quality of the current virtual microscopy systems is suitable for clinical, educational, and research purposes. The efficient use of digital microscopy by means of image analysis systems can offer important benefits to pathology departments.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1066-8969 1940-2465
DOI:	10.1177/1066896906292274