Search Results - "Mateo, Sara De"
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Reprogramming of the Circadian Clock by Nutritional Challenge
Published in Cell (19-12-2013)“…Circadian rhythms and cellular metabolism are intimately linked. Here, we reveal that a high-fat diet (HFD) generates a profound reorganization of specific…”
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2
Regulation of spermatogenesis by small non-coding RNAs: Role of the germ granule
Published in Seminars in cell & developmental biology (01-05-2014)“…•Small non-coding RNAs are crucial for the development of the male germ cell.•sncRNAs operate through post-transcriptional regulatory mechanisms.•miRNA and…”
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3
Atlas of Circadian Metabolism Reveals System-wide Coordination and Communication between Clocks
Published in Cell (06-09-2018)“…Metabolic diseases are often characterized by circadian misalignment in different tissues, yet how altered coordination and communication among tissue clocks…”
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4
Proteomic characterization of the human sperm nucleus
Published in Proteomics (Weinheim) (01-07-2011)“…Generating a catalogue of sperm nuclear proteins is an important first step towards the clarification of the function of the paternal chromatin transmitted to…”
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5
A Point-of-Care Device for Fully Automated, Fast and Sensitive Protein Quantification via qPCR
Published in Biosensors (Basel) (19-07-2022)“…This paper presents a fully automated point-of-care device for protein quantification using short-DNA aptamers, where no manual sample preparation is needed…”
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Protamine 2 precursors (Pre-P2), protamine 1 to protamine 2 ratio (P1/P2), and assisted reproduction outcome
Published in Fertility and sterility (01-03-2009)“…Objective To determine whether the presence of protamine 2 precursors (pre-P2/P2 ratio) and the protamine 1 to protamine 2 ratio (P1/P2) are related to the…”
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Circadian proteins CLOCK and BMAL1 in the chromatoid body, a RNA processing granule of male germ cells
Published in PloS one (10-08-2012)“…Spermatogenesis is a complex differentiation process that involves genetic and epigenetic regulation, sophisticated hormonal control, and extensive structural…”
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8
Adapting ISFETs for Epigenetics: An Overview
Published in IEEE transactions on biomedical circuits and systems (01-10-2018)“…This paper gives an overview of how CMOS design methods can be applied to ion-sensitive field effect transistor (ISFETs) for pH-based DNA methylation and miRNA…”
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9
Assessment of the impact of a personalised nutrition intervention in impaired glucose regulation over 26 weeks: a randomised controlled trial
Published in Scientific reports (05-03-2024)“…Dietary interventions can reduce progression to type 2 diabetes mellitus (T2DM) in people with non-diabetic hyperglycaemia. In this study we aimed to determine…”
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10
Protamine 2 precursors and processing
Published in Protein and peptide letters (01-08-2011)“…Protamine 2 (P2) is synthesised as a precursor protein (pre-P2) which by proteolysis is processed to generate the mature components of the protamine 2 family…”
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11
Detection of MGMT methylation status using a Lab-on-Chip compatible isothermal amplification method
Published in 2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) (01-11-2021)“…The growing cancer burden necessitates the development of cost-effective solutions that provide rapid, precise and personalised information to improve patient…”
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Sperm cell proteomics
Published in Proteomics (Weinheim) (01-02-2009)“…The spermatozoon is an accessible cell which can be easily purified and therefore it is particularly well suited for proteomic analysis. It is also an…”
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13
Identification of proteomic differences in asthenozoospermic sperm samples
Published in Human reproduction (Oxford) (01-04-2008)“…BACKGROUND Asthenozoospermia is one of the most common findings present in infertile males, but its aetiology remains unknown in most cases. Present proteomic…”
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14
Aptasensor for Quantification of Leptin Through PCR Amplification of Short DNA-Aptamers
Published in ACS sensors (26-03-2021)“…Protein quantification is traditionally performed through enzyme-linked immunosorbent assay (ELISA), which involves long preparation times. To overcome this,…”
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Assessing a novel, lab-free, point-of-care test for SARS-CoV-2 (CovidNudge): a diagnostic accuracy study
Published in The Lancet. Microbe (01-11-2020)“…Access to rapid diagnosis is key to the control and management of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Laboratory RT-PCR testing is…”
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A Point-of-Care Device for Sensitive Protein Quantification
Published in 2021 IEEE International Symposium on Circuits and Systems (ISCAS) (01-05-2021)“…In this paper we present the design of a new point-of-care device for protein quantification. The proposed design is based on a novel aptamer-mediated…”
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Conference Proceeding -
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Marked correlations in protein expression identified by proteomic analysis of human spermatozoa
Published in Proteomics (Weinheim) (01-12-2007)“…The present work was started to explore whether a correlation could be detected among proteomic expression, protamine content and DNA integrity in human sperm…”
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18
Protamine/DNA Ratios and DNA Damage in Native and Density Gradient Centrifuged Sperm From Infertile Patients
Published in Journal of andrology (01-05-2011)“…Protamines are the major nuclear proteins condensing DNA in the sperm nucleus. One of their proposed functions is the protection of the genetic message…”
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Methods for the analysis of the sperm proteome
Published in Methods in molecular biology (Clifton, N.J.) (2013)“…Proteomics is the study of the proteins of cells or tissues. Sperm proteomics aims at the identification of the proteins that compose the sperm cell and the…”
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Live demonstration: A CMOS-based ISFET array for rapid diagnosis of the Zika virus
Published in 2017 IEEE International Symposium on Circuits and Systems (ISCAS) (01-05-2017)“…We demonstrate a diagnostics platform which integrates an ISFET array and a temperature control loop for isothermal DNA detection. The controller maintains a…”
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Conference Proceeding