Search Results - "Mateo, George"

Alternative stabilities of a proline‐rich antibacterial peptide in vitro and in vivo by Noto, Paul Bart, Abbadessa, Giovanni, Cassone, Marco, Mateo, George D., Agelan, Alexis, Wade, John D., Szabo, Dora, Kocsis, Bela, Nagy, Karoly, Rozgonyi, Ferenc, Otvos, Laszlo

“…The proline‐rich designer antibacterial peptide dimer A3‐APO is currently under preclinical development for the treatment of systemic infections caused by…”
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Agonists and partial antagonists acting on the leptin--leptin receptor interface by Otvos, Jr, Laszlo, Cassone, Marco, Terrasi, Marianna, Cascio, Sandra, Mateo, George D, Knappe, Daniel, Hoffmann, Ralf, Cudic, Predrag, Wade, John D, Surmacz, Eva

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Novel inhibitors of Staphylococcus aureus RnpA that synergize with mupirocin by Lounsbury, Nicole, Eidem, Tess, Colquhoun, Jennifer, Mateo, George, Abou-Gharbia, Magid, Dunman, Paul M., Childers, Wayne E.

“…We recently discovered RnpA as a promising new drug discovery target for methicillin-resistant S. aureus (MRSA). RnpA is an essential protein that is thought…”
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Discovery and SAR of Novel Disubstituted Quinazolines as Dual PI3Kalpha/mTOR Inhibitors Targeting Breast Cancer by Al-Ashmawy, Aisha A. K, Elokely, Khaled M, Perez-Leal, Oscar, Rico, Mario, Gordon, John, Mateo, George, Omar, Abdelsattar M, Abou-Gharbia, Magid, Childers, Wayne E

“…The dual PI3Kα/ m TOR inhibitors represent a promising molecularly targeted therapy for cancer. Here, we documented the discovery of new 2,4-disubstituted…”
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Heterocyclic chalcone activators of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) with improved in vivo efficacy by Lounsbury, Nicole, Mateo, George, Jones, Brielle, Papaiahgari, Srinivas, Thimmulappa, Rajash K., Teijaro, Christiana, Gordon, John, Korzekwa, Kenneth, Ye, Min, Allaway, Graham, Abou-Gharbia, Magid, Biswal, Shyam, Childers, Wayne

“…[Display omitted] Nrf2 activators represent a good drug target for designing agents to treat diseases associated with oxidative stress. Building upon previous…”
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Design, synthesis and SAR of new-di-substituted pyridopyrimidines as ATP-competitive dual PI3Kα/mTOR inhibitors by Al-Ashmawy, Aisha A.K., Ragab, Fatma A., Elokely, Khaled M., Anwar, Manal M., Perez-Leal, Oscar, Rico, Mario C., Gordon, John, Bichenkov, Eugeney, Mateo, George, Kassem, Emad M.M., Hegazy, Gehan H., Abou-Gharbia, Magid, Childers, Wayne

“…[Display omitted] PI3Kα/mTOR ATP-competitive inhibitors are considered as one of the promising molecularly targeted cancer therapeutics. Based on lead compound…”
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